[PDF] Top 20 Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
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Human Herpesvirus 7 U21 Tetramerizes To Associate with Class I Major Histocompatibility Complex Molecules
... that U21 interacts with class I MHC molecules in a 4:2 ratio contributes to our understanding of these ...of U21 oligomerization should reduce the efficiency of U21 ... See full document
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Human Herpesvirus 7 U21 Downregulates Classical and Nonclassical Class I Major Histocompatibility Complex Molecules from the Cell Surface
... from human cytomegalovirus (HCMV) (54, 57). We do not know how HHV-7 responds to the selective pressures exerted by NK ...that U21 can associate with and downregulate HLA-A and -B, but we do ... See full document
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A Human Herpesvirus 7 Glycoprotein, U21, Diverts Major Histocompatibility Complex Class I Molecules to Lysosomes
... the herpesvirus family persist in their host throughout ...system. Human herpesvirus 7 (HHV-7) is a relatively recently discovered member of the herpesvirus family, and little is ... See full document
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Downregulation of Major Histocompatibility Complex Class I Molecules by Kaposi's Sarcoma-Associated Herpesvirus K3 and K5 Proteins
... While the dramatic downregulation of HLA allotypes by K3 likely confers a protection from killing by CTLs, its indiscrim- inate downregulation of HLA-C and -E may invite NK cells to attack infected cells. To protect ... See full document
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Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules
... The human cytomegalovirus US3, an endoplasmic reticulum (ER)-resident transmembrane glycoprotein, forms a complex with major histocompatibility complex (MHC) class I ... See full document
8
Human Cytomegalovirus-Encoded Immune Modulators Partner To Downregulate Major Histocompatibility Complex Class I Molecules
... the human cytomegalovirus (HCMV) has developed a variety of strategies to avoid immune recognition and ...The major histocompatibility complex (MHC) class I antigen presentation ... See full document
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Placental Extravillous Cytotrophoblasts Persistently Express Class I Major Histocompatibility Complex Molecules after Human Cytomegalovirus Infection
... MHC class I sensi- tivity may be ...the class I MHC molecules in EVT was not affected by HCMV infection, we did not use specific antibodies against either HLA-C, -E, or -G in this ...-G ... See full document
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Physical Association of the K3 Protein of Gamma-2 Herpesvirus 68 with Major Histocompatibility Complex Class I Molecules with Impaired Peptide and β2-Microglobulin Assembly
... of major histocompatibility complex class I molecules by using a variety of ...gamma-2 herpesvirus 68 expresses the K3 protein, which causes the rapid turnover of nascent ... See full document
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Characterization of a Murine Cytomegalovirus Class I Major Histocompatibility Complex (MHC) Homolog: Comparison to MHC Molecules and to the Human Cytomegalovirus MHC Homolog
... these molecules both function as surrogate class I pro- teins, capable of engaging NK cell inhibitory receptors and protecting cells that lack class I surface ...characterized ... See full document
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Major histocompatibility complex class I-restricted cytotoxic T-lymphocyte responses in horses infected with equine herpesvirus 1.
... equine herpesvirus 1 (EHV-1)-specific cytotoxic T-lymphocyte (CTL) activity in the horse was ...by major histocompatibility complex class I ... See full document
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Analysis of Pigtail Macaque Major Histocompatibility Complex Class I Molecules Presenting Immunodominant Simian Immunodeficiency Virus Epitopes
... MHC class I molecule most commonly presenting the immunodominant KP9 epitope, we selectively transfected a human cell line with full-length ...MHC class I cDNA from 12 pigtail macaques ... See full document
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GRP78, a Coreceptor for Coxsackievirus A9, Interacts with Major Histocompatibility Complex Class I Molecules Which Mediate Virus Internalization
... MHC-I molecules associate using the FRET methodology, which is a noninvasive technique that allows us to study receptor interactions on the cell ... See full document
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Cellular and Molecular Requirements for Association of the Murine Cytomegalovirus Protein m4/gp34 with Major Histocompatibility Complex Class I Molecules
... vector, complex formation was even observed in  2 m ⫺/⫺ ...b complex formation between the ER and dilute detergent ...the molecules apart and only allow m4/gp34 access to MHC class I ... See full document
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Human Cytomegalovirus Protein pp71 Disrupts Major Histocompatibility Complex Class I Cell Surface Expression
... MHC class I downmodulation is a consequence of a function for pp71 in altering the trafficking of glycoproteins, possibly relevant to virus ...MHC class I represents a specific viral immune ... See full document
13
Binding of Human Cytomegalovirus US2 to Major Histocompatibility Complex Class I and II Proteins Is Not Sufficient for Their Degradation
... unglycosylated molecules, with the latter lacking N-linked oligosaccharides (40, 42, ...US2 molecules that me- diated degradation displayed rapid and preferential loss of the unglycosylated ...MHC ... See full document
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Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-Loading Complex and Inhibits Tapasin Gene Transcription
... 2011 Major histocompatibility complex class I (MHC I) molecules present antigenic peptides for CD8 ⴙ T-cell recog- ...MHC I loading is conducted by the ... See full document
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Major Histocompatibility Complex Class I Downregulation Induced by Equine Herpesvirus Type 1 pUL56 Is through Dynamin-Dependent Endocytosis
... We were able to demonstrate here that EHV-1 pUL56 colocal- izes from 4 h p.i. with MHC-I-containing vesicles and the lyso- somal marker LAMP-1 in infected cells. This colocalization cor- relates with decreased ... See full document
14
The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II Molecules
... surface major histocompatibility complex (MHC) and immunostimulatory molecules required for recognition and lysis by virus-specific cytotoxic T ...MHC class I molecules ... See full document
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Downregulation of Major Histocompatibility Complex Class I by Human Ubiquitin Ligases Related to Viral Immune Evasion Proteins
... these molecules resistant to MARCH-IV or MARCH-IX downregulation ...target molecules in such a way that they are no longer recognized by MARCH-IV or -IX, we introduced a lysine residue into an HA tag at the ... See full document
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Identification and Characterization of Equine Herpesvirus Type 1 pUL56 and Its Role in Virus-Induced Downregulation of Major Histocompatibility Complex Class I
... thesized MHC-I to the cell surface is blocked (29). This finding may explain that the dramatic downregulation of MHC-I at early times of infection is likely not caused by interference of pUL49.5 with TAP. ... See full document
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