[PDF] Top 20 Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That Is Dispensable for Cell Cycle Arrest at Phase G2/M
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Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That Is Dispensable for Cell Cycle Arrest at Phase G2/M
... that replication of the B19V dsDNA genome induces DDR signaling and that the DDR is dispensable for triggering cell cycle arrest during B19V DNA rep- .../M ... See full document
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DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1
... promoting cell survival after DNA damage, the exact mechanisms are not well ...the DNA damage response is less well ...by DNA damage in an ATM and ATR-dependent ... See full document
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Human Parvovirus B19 Induces Cell Cycle Arrest at G2 Phase with Accumulation of Mitotic Cyclins
... 2001 Human parvovirus B19 infects specifically erythroid progenitor cells, which causes transient aplastic crises and hemolytic ...with B19 virus fall into growth arrest with 4N ... See full document
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Human Parvovirus B19 Infection Causes Cell Cycle Arrest of Human Erythroid Progenitors at Late S Phase That Favors Viral DNA Replication
... characterize cell cycle arrest during B19V infection of EPCs, we analyzed the cell cycle change using 5-bromo-2=-deoxyuri- dine (BrdU) pulse-labeling and DAPI ... See full document
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Human Parvovirus B19 Nonstructural Protein (NS1) Induces Cell Cycle Arrest at G1 Phase
... 2002 Human parvovirus B19 infects predominantly erythroid precursor cells, leading to inhibition of erythropoi- ...erythroid cell damage is mediated by the viral nonstructural protein 1 ... See full document
7
Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells
... in cell growth, angiogenesis, and can be applied toward macrovascular invasion and extra hepatic metastasis ...In response to the anticancer drug-re- sistance of HCC, some second-line anticancer drugs have ... See full document
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Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication
... and Cell Biology, University of Kansas Medical Center, Kansas City, Kansas, USA d ViraCor Eurofins Laboratories, Lee's Summit, Missouri, USA ABSTRACT Human parvovirus B19 (B19V) infection of ... See full document
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Bocavirus Infection Induces Mitochondrion-Mediated Apoptosis and Cell Cycle Arrest at G2/M Phase
... a DNA damage response represented by phosphorylation of H2AX, p53, and ATM (data not ...The DNA damage response induces apoptosis when the damage is not repairable ... See full document
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Bocavirus Infection Induces a DNA Damage Response That Facilitates Viral DNA Replication and Mediates Cell Death
... autonomous parvovirus that replicates efficiently without helper viruses in Walter Reed/3873D (WRD) canine ...infection induces mitochondrion- mediated apoptosis and G 2 /M-phase arrest ... See full document
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The Putative Metal Coordination Motif in the Endonuclease Domain of Human Parvovirus B19 NS1 Is Critical for NS1 Induced S Phase Arrest and DNA Damage
... the parvovirus family are highly conserved mul- ti-functional molecules that have been extensively characterized and shown to be integral to viral ...bind DNA and act as nucleases in order to resolve the ... See full document
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DNA hypomethylation induces a DNA replication associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos
... the response to Uhrf1 depletion. uhrf1 mutant cells undergo cell cycle arrest Our findings suggest either that uhrf1 mutant hepatocytes are hyperproliferative, which is inconsistent with the ... See full document
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Human Papillomavirus E7 Induces Rereplication in Response to DNA Damage
... how DNA damage enhances re- replication in E7-expressing cells is still not clear, since the level of Cdt1 is not further increased in these cells upon DNA ...for DNA ... See full document
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EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage
... induce DNa damage Conclusion In the present study, we have demonstrated 225-NP treat- ment of EGFR-positive HCC827 lung cancer cells resulted in abrogation of cell cycle arrest in the ... See full document
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Baculovirus Infection Induces a DNA Damage Response That Is Required for Efficient Viral Replication
... cellular DNA damage response during replication, and in some cases, this response is required for optimal virus ...a DNA damage response is stimulated by DNA ... See full document
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A novel topoisomerase I inhibitor DIA 001 induces DNA damage mediated cell cycle arrest and apoptosis in cancer cell
... on DNA (5,6). (II) Topo1 catalytic inhibitors, which prevent DNA cleavage ...the DNA replication process, induces cell cycle arrest at the G2/M ... See full document
8
Cordyceps cicadae induces G2/M cell cycle arrest in MHCC97H human hepatocellular carcinoma cells: a proteomic study
... in cell cycle regulation, G2/M checkpoint control, microtubule polymerization, and spindle organization during mitosis ...the G2/M cell cycle arrest induced ... See full document
12
An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus
... DNA damage resulting from intrinsic or extrinsic sources activates DNA damage responses (DDRs) centered on protein kinase signaling ...of cell cycle checkpoints together with ... See full document
12
Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors
... B19V replication and propagation, but not NS1 alone, appear mainly responsible for induction of the DNA damage ...2 arrest during B19V infection, allowing B19V to “hijack” host cell ... See full document
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Human Herpesvirus 6 Suppresses T Cell Proliferation through Induction of Cell Cycle Arrest in Infected Cells in the G2/M Phase
... the cell cycle in infected cells is a common strategy used by many viruses to regulate their ...of cell cycle arrest in the G 2 /M phase in infected cells, resulting from ... See full document
10
Rotavirus replication is correlated with S/G2 interphase arrest of the host cell cycle
... infection induces cell cycle arrest independently of the cell type Following this line of thought, we investigated whether RV infection also arrests the cell cycle in ... See full document
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