[PDF] Top 20 Identification of endogenous retroviral reading frames in the human genome
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Identification of endogenous retroviral reading frames in the human genome
... the identification of two novel env genes in this survey make expression analysis and functional assess- ment a difficult ...our genome-wide HERV data as well as predictions of Gag, Pol and Env read- ing ... See full document
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Identification of Long-Range Regulatory Elements in the Human Genome
... the Human Genome Abstract Genome-wide association studies have shown that the majority of disease-associated genetic variants lie within non-coding regions of the human ...interactions ... See full document
141
De novo identification of differentially methylated regions in the human genome
... The identification and characterisation of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in ...the genome using a Gaussian ...the ... See full document
16
De novo identification of differentially methylated regions in the human genome
... The identification and characterisation of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in ...the genome using a Gaussian ...the ... See full document
19
Identification and Prioritisation of Variants in the Short Open-Reading Frame Regions of the Human Genome
... whole genome sequence produces roughly 1 billion reads, which contain on average 3 million ...the genome, where significantly different distributions of each metric are ... See full document
29
Identification and Characterization of Novel Human Endogenous Retrovirus Families by Phylogenetic Screening of the Human Genome Mapping Project Database
... 2000 Human endogenous retroviruses (HERVs) were first identified almost 20 years ago, and since then numerous families have been ...the Human Genome Mapping Project database, and a variety of ... See full document
16
Identification and Mapping of Origins of DNA Replication in the Human Genome
... 2 Methods and Materials An overall experimental strategy of the nascent DNA enrichment determination using genomic microar- rays and next-generation sequencing is shown in Figure 1. Briefly, nascent DNA strands extruded ... See full document
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Endogenous retroviruses in the human genome sequence
... HERVs and disease HERVs have frequently been proposed as etiological cofac- tors in chronic diseases such as cancer, autoimmunity and neurological disease [13]. Unfortunately, despite intense effort from many groups, ... See full document
5
Human endogenous retroviral elements promote genome instability via non-allelic homologous recombination
... The identification of deletions and reciprocal duplications mediated by HERV elements and their association with recombination hotspot motifs further strengthens the hypothesis that these CNVs arise via ... See full document
10
The identification and classification of endogenous retroviruses in the horse genome
... ancient retroviral infections of germ cells and integrated in humans, mammals and other vertebrates millions years ...open reading frames in their ...equine endogenous beta retrovirus which is ... See full document
6
Characterization of Human Endogenous Retroviral Elements in the Blood of HIV-1-Infected Individuals
... type 1-type 2 recombinants in sequences downstream of the 292-bp fragment from type 2 proviruses. This recombination hot spot increases the possibility that intact type 1 env genes restore coding capacity after regaining ... See full document
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Human Endogenous Retroviral Elements as Indicators of Ectopic Recombination Events in the Primate Genome
... the human genome, but, because of their tendency to mediate ectopic recombi- nation events and undergo concerted evolution, care must be taken when they are utilized in phylogenetic ...the genome for ... See full document
12
Unfixed Endogenous Retroviral Insertions in the Human Population
... of human endogenous retroviruses (HERVs), HERV-K(HML2), is upregulated in many cancers, some autoimmune/ inflammatory diseases, and HIV-infected ...the human reference genome se- ...the ... See full document
9
Endogenous retroviral promoter exaptation in human cancer
... However, other studies have shown no significant changes in ERV expression in selected human cancers compared to corresponding normal tissues [110, 111]. General conclusions about overall TE transcriptional ... See full document
21
Characterization of human endogenous retroviral envelope RNA transcripts.
... DNA sequence analysis of a partial cDNA clone, pPL1, of the 1.7-kb RNA has revealed that in comparison with a cloned, full-length, endogenous provirus, 4-1, pPL1 contains a 938-bp deleti[r] ... See full document
7
A revised nomenclature for transcribed human endogenous retroviral loci
... In order for the nomenclature scheme to be systema- tic, one method of sorting ERVs into groups needed to be selected. The Repbase system [6] is a widely known, comprehensive database of repetitive elements that groups ... See full document
8
Amplification and chromosomal dispersion of human endogenous retroviral sequences.
... The initial results suggest that, like some of the class of truncated endogenous retroviral segments, some members of the full-length human retroviral family were also amplified and phys[r] ... See full document
6
Packaging of Endogenous Retroviral Sequences in Retroviral Vectors Produced by Murine and Human Packaging Cells
... The human packaging cell line FLYA4L3 expresses high levels of MLV Gag-Pol proteins, producing virions at titers 10- to 100-fold higher than those obtained with murine packaging cell lines, such as ...MFGnlsLacZ ... See full document
6
Identification of proteins encoded by the L1 and L2 open reading frames of human papillomavirus 1a.
... blotting, antiserum prepared against the Li (pLl-776) fusion protein detected the major 57,000-molecular-weight HPV-1 structural protein (57K protein) consistently in extracts of warts i[r] ... See full document
7
Nucleotide sequence of a full-length human endogenous retroviral segment.
... junction in clone 4-1 was identified by the presence of identical deduced amino acids (Asp-End-Gly-Gly) (Fig. 4B) in both the MoMuLV genome and the human retroviral sequences. Within the[r] ... See full document
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