[PDF] Top 20 Impact of overweight on left ventricular function in type 2 diabetes mellitus

... dys- function than normotensive patients with either con- dition ...that left atrial strain as assessed by cardiac magnetic resonance imaging was a sensitive tool for the detection of early LV diastolic ... See full document

... with diabetes (so called diabetic cardiomyopa- thy) remain unclear, several factors such as a metabolic abnormality, autonomic dysfunction, myocardial fibrosis and reduced perfusion due to small vessel disease, ... See full document

... Diabetes mellitus is a complex metabolic disease characterized by a primary defect in carbohydrate metabolism associated with protein and fat metabolism and modulated by genetic, HLA and environmental ... See full document

... co-morbidities; this has reduced the applicability of our results to “real world” populations with high incidence of co-morbidities. However, we recruited such partici- pants as this design excluded the effects of ... See full document

... of Left ventricular dysfunction was a prospective, randomized, open, blinded, end-point (PROBE) designed ...T2DM, overweight, hypertension, family history of HF, cardiotoxin exposure and known ... See full document

... and diabetes (screening visits consisted of a medical history, physical examina- tion, an ECG and screening laboratory tests such as fasting plasma glucose, lipids and ... See full document

... In this regard, urinary albumin excretion (UAE) may have a role as an early indicator for the future development of diabetic vascular complications and LVH. UAE has conventionally been divided into microalbuminuria and ... See full document

... the left ventricle (LV) were taken at cordal level, with the patient in partial left decubitus position, and three to five measurements were ...The left ven- tricular mass (LVM) was calculated by the ... See full document

... It has been widely reported that GLS in conjunction with HF stage classification is more useful for HF patient man- agement than conventional echocardiographic parame- ters, even in patients with findings other than ... See full document

... diastolic function play a major role in producing the signs and symptoms of heart ...systolic function, implicating Diastolic Dysfunction as a major pathophysiologic ... See full document

... of left ventricular systolic and diastolic function in patients with early stage of type 2 diabetes, without coronary artery disease, with or without ...with type 2 ... See full document

... DM diabetes mellitus, BSA body surface area, BNP plasma brain natriuretic peptide, LDL low density lipoprotein, HDL high density lipoprotein, HFpEF heart failure with preserved ejection fraction, HFrEF ... See full document

... The mean peak velocity of early mitral flow (E) value was 69.44. The mean peak velocity of late mitral flow (A) value 67.63, pressure half time (PHT) was 58.80, Isovolumic relaxation time (IRT) was 83.53, E/A ratio was ... See full document

... with type 1 diabetes mellitus (T1DM) imaging studies have demonstrated an increased prevalence of left ventricular diastolic dysfunction and increased left ventricular ... See full document

... All patients had a resting transthoracic echocardio- gram (Philips HDI 5000/iE33, Bothell, Seattle, Washing- ton) which was the reference standard for the detection of LVH in this study performed by a research-trained ... See full document

... Carotid ultrasound was performed by a single opera- tor (CM) on the right common carotid artery using an ultrasound scanner equipped with a 10 MHz linear probe (MyLab 70, Esaote, Genova, Italy) and implemented with a ... See full document

... following left ventricle function parameters was taken: Left ventricular internal dimensions: EDD and ESD (mm), Interventricular septal thickness in systole and diastole: IVSS and IVSD ... See full document

... Continuous variables were expressed as mean values with SD for normally distributed data and as medians values with interquartile range for non-normally distributed data. Categorical variables were expressed as ... See full document

... before diabetes become clinically ...of diabetes do not become evident until a majority (>80%) of β cells are ...frank diabetes are associated with increased insulin requirements, as might occur ... See full document

... Patients with DM have been shown to have impaired LV diastolic function. This is also evident in the present study which demonstrated that such patients had a lower resting e 0 despite a similar LV mass index, LV ... See full document