[PDF] Top 20 IMPROVEMENT IN MICROMERITIC PROPERTIES AND DISSOLUTION RATE OF GLIMEPIRIDE
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IMPROVEMENT IN MICROMERITIC PROPERTIES AND DISSOLUTION RATE OF GLIMEPIRIDE
... of glimepiride by solvent evaporation method The SDs of glimepiride with different hydrophilic carriers such as PEG6000, PEG10000 and Gelucire 44/14 containing three different weight ratios (1:1, 1:3, 1:5) ... See full document
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SPHERICAL CRYSTALLIZATION OF ZALTOPROFEN FOR ENHANCEMENT OF MICROMERITIC PROPERTIES AND DISSOLUTION RATE
... The main factor in the improvement of flowability and packability was due to their spherical shapes and smooth surfaces. The agglomerates have shown improved in-vitro drug release performance comparable with ... See full document
7
FORMULATION AND EVALUATION OF SPHERICAL CRYSTALS OF INDOMETHACIN FOR THE IMPROVEMENT OF SOLUBILITY AND MICROMERITIC PROPERTIES
... Spherical crystallization is an effective alternative to improve the dissolution rate of drugs 4 . This can be achieved by various methods such as spherical agglomeration, quasi-emulsion solvent diffusion, ... See full document
8
AMELIORATED SOLUBILITY AND DISSOLUTION RATE OF GLIMEPIRIDE BY CYCLODEXTRIN TERNARY COMPLEXES EMPLOYING AMINOACIDS
... and dissolution rate of ...an improvement in the solid pharmaceutical formulations of the Glimiperide, which renders sufficiently the formulation aqueous soluble for clinical ... See full document
9
Formulation of Tablets Containing Glimepiride-loaded Mesoporous Silica Particles
... pure glimepiride, MCM/ glimepiride and HMS/glimepiride ...pure glimepiride showed dissolution of 30 % for two hours. Glimepiride released from tablets prepared with MCM and ... See full document
6
Improvement of Solubility and Dissolution Properties of Clotrimazole by Solid Dispersions and Inclusion Complexes
... The extent of drug release was assessed from the total amount of drug present in the release medium at the end of the 360 min drug release experiment. The type of drug release kinetics applicable for the suppository ... See full document
10
Improvement in Dissolution Rate of Cefuroxime Axetil by using Poloxamer 188 and Neusilin US2
... poured into a 50 ml glass measuring cylinder, the heap of the particles in the cylinder was levelled off horizontally with a thin metallic spatula, and the bulk volume, Vo, was accurately measured. The cylinder was then ... See full document
9
Improvement of dissolution rate of diacerein using liquisolid technique
... flow properties of the granules are vital for the performance of the ...the properties of the liquisolid powders were analysed before filling into the empty gelatin ...flow properties, hence ... See full document
11
FORMULATION AND CHARACTERIZATION OF LIQUISOLID TABLETS OF VALSARTAN FOR IMPROVEMENT OF DISSOLUTION RATE
... Materials and Methods: Different LS compacts were prepared using a mathematical model for calculating required quantities of powder and liquid ingredients to produce an acceptably flowable and compressible admixture. ... See full document
6
Liquisolid Compact Technique for Improvement of the Dissolution Rate of Flurbiprofen: Formulation and Evaluation
... Liquisolid powder mixtures of different formulations were evaluated for angle of repose, bulk density, tapped density and compressibility index. The fixed funnel method was employed to measure the angle of repose (θ) and ... See full document
5
Modification of physicochemical and micromeritic properties of active pharmaceutical ingredient by crystallization technique
... dissolved drug. The crystallisation of drug takes place inside the droplets due to counter diffusion of acetone through droplets. The average size of the agglomerates increased with increasing the volume of acetone. This ... See full document
5
SOLUBILITY IMPROVEMENT USING SOLID DISPERSION; STRATEGY, MECHANISM AND CHARACTERIZATION: RESPONSIVENESS AND PROSPECT WAY OUTS
... The properties of the carrier have a major influence on the dissolution characteristics of the dispersed ...the dissolution rate of a drug: be freely water-soluble with intrinsic rapid ... See full document
6
Cocrystal habit engineering to improve drug dissolution and alter derived powder properties
... physicochemical properties of the ...The dissolution properties were also affected by the cocrystal habit resulting in a higher overall dissolution rate in deionised water for milled ... See full document
26
IMPROVEMENT OF SOLUBILITY AND DISSOLUTION RATE OF CANDESARTAN CILEXETIL BY SOLID DISPERSION IN POLYVINYL PYRROLIDONE
... its dissolution rate is very low 6 ...physicochemical properties of different systems were determined from DSC and XRD ...on dissolution properties of CC in SDs was ... See full document
7
IMPROVEMENT OF DISSOLUTION PROPERTIES OF ALBENDAZOLE FROM DIFFERENT METHODS OF SOLID DISPERSION
... The term solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. Solid dispersions are a useful pharmaceutical ... See full document
6
Preparation and Characterization of Spherical Agglomerates of Gliclazide
... The micromeritic properties such as flowability, packability and compactibility of agglomerates were significantly improved compared to pure ...and dissolution rate of agglomerates was due to ... See full document
6
APPLICATION OF SPHERICAL AGGLOMERATION TECHNIQUE TO IMPROVE MICROMERITIC PROPERTIES AND DISSOLUTION CHARACTERISTICS OF NABUMETONE
... and dissolution rate of Nabumetone, 4-(6-methoxy-2-naphalenyl)-2-butanone water insoluble anti- inflammatory drug by spherical agglomeration technique using a solvent change method consisting of acetone, ... See full document
7
Spherical Crystals of Moxifloxacin: To Improve Solubility, Dissolution Rate and Micromeritic Properties
... and micromeritic properties.To improve these properties Agglomerated crystals of moxifloxacin were prepared by a spherical crystallization technique using the ammonia diffusion system ...micromeritics ... See full document
11
PREPARATION AND CHARACTERIZATION OF GLIPIZIDE SPHERICAL AGGLOMERATES BY DIRECT COMPRESSION METHOD USING DIFFERENT POLYMERS AND ITS EVALUATION
... improved micromeritic properties (bulk density, tapped density, compressibility index, angle of ...and dissolution rates were faster and exhibited improved solubility, dissolution rate ... See full document
9
Development of Controlled Release Tablets of Nisoldipine with Improved Pharmaceutical Properties
... superior dissolution properties when compared to PM, pure NIS and the improvement in dissolution rate values were in the order of KS > PM > pure ...The dissolution ... See full document
9
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