[PDF] Top 20 Increased expression of complement decay accelerating factor during activation of human neutrophils
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Increased expression of complement decay accelerating factor during activation of human neutrophils
... Upon activation, the affected PMN lacking surface DAF from patients with paroxysmal nocturnal hemoglobulinuria failed to increase DAF ...cells increased CR1 and CR3 expression normally, suggesting ... See full document
8
Protective effects of decay-accelerating factor on blast-induced neurotrauma in rats
... creased expression of C5aR and interaction of C5a-C5aR was not observed in this study (data not shown), it is very likely that early tau phosphorylation is regulated by the enhanced C3a-C3aR signaling axis in our ... See full document
15
A comparative quantitative LC MS/MS profiling analysis of human pancreatic adenocarcinoma, adjacent normal tissue, and patient derived tumour xenografts
... [31]. Complement decay-accelerating factor (CD55) has been identified by immunohistochemistry in pancreatic cancer, and its elevated levels correlate positively with tumour aggressiveness, ... See full document
20
Human neutrophils increase expression of C3bi as well as C3b receptors upon activation
... the expression of the receptors for the complement fragments C3bi (CR3) and C3b (CR1) on human polymorphonuclear neutrophil leukocytes ...(PMN). Expression of both receptors was minimal on ... See full document
7
Statin induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti inflammatory actions of statins in rheumatoid arthritis
... its expression is reported to be reduced in rheumatoid synovium when compared with noninflamed tissue ...of human CD59, increased disease sever- ity in an antigen-induced arthritis model, a phenotype ... See full document
12
Decay accelerating factor is expressed on vascular smooth muscle cells in human atherosclerotic lesions
... glycoprotein on blood cells and endothelium that inhibits cell surface C3/C5 convertase formation, thus inhibiting complement activation and protecting cells from lysis by the terminal complement ... See full document
9
The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
... the complement system and, together with membrane cofactor protein, complement receptor types 1 and 2, and C4- binding protein, is a member of the family of regulators of complement activation ... See full document
10
Decay accelerating factor protects human tumor cells from complement mediated cytotoxicity in vitro
... in complement mediated cytotoxicity, complement- insensitive melanoma cell lines were compared with respect to expression of the decay- accelerating factor (DAF), a membrane ... See full document
8
Novel Role for Decay-Accelerating Factor in Coxsackievirus A21-Mediated Cell Infectivity
... Decay-accelerating factor (DAF) is involved in the cell membrane attachment of many human ...virus increased in a linear fashion with respect to temperature and ... See full document
6
Acquisition of Complement Resistance through Incorporation of CD55/Decay-Accelerating Factor into Viral Particles Bearing Baculovirus GP64
... with human DAF and a marker protein of lipid rafts, caveolin 1, but not with calreti- culin, a marker protein of endoplasmic reticulum, indicating that GP64 colocalized with GPI-anchored proteins including ... See full document
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NFκB Is Persistently Activated in Continuously Stimulated Human Neutrophils
... Increased activation of the transcription factor NFκB in the neutrophils has been associated with the pathogenesis of sepsis, acute lung injury (ALI), bronchopulmonary dysplasia (BPD), and ... See full document
9
Identification of a third component of complement binding glycoprotein of human platelets
... from decay accelerating factor (DAF), a complement regulatory protein previously identified on human platelet ...no decay accelerating ... See full document
9
Expression of glycoprotein gIII-human decay-accelerating factor chimera on the bovine herpesvirus 1 virion via a glycosyl phosphatidylinositol-based membrane anchor.
... We wished to examine i whether the putative transmembrane domain could indeed function as a membrane anchor for the presentation of gIII on the surfaces of infected cells and on the viri[r] ... See full document
9
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury
... sections. Human disease rel- evance was confirmed by laser-capture microdissection of alveolar septae, which demonstrated marked upregulation of FX mRNA levels in IPF ... See full document
15
A proteomic approach to understanding the pathogenesis of idiopathic macular hole formation
... Six molecular chaperone proteins involved in the proper folding of proteins were downregulated in IMH: T-complex protein 1 subunit ζ, heat shock protein β-1, heat shock 70 kDa protein 1A, UDP-glucose:glycoprotein, ... See full document
10
Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor
... A further mode of membrane internalization that is less well studied as a potential viral transport system is that through cellular structures referred to as caveolae (35, 36). We would suggest that MAb-cross-linked DAF ... See full document
6
Low pH results in co ordinate regulation of gene expression in oesophageal cells
... whose expression was upregulated across all time periods in comparison with the resting ...an increased expression of decay accelerating factor (DAF) was observed, which has ... See full document
9
Inhibition of the activation of Hageman factor (factor XII) by complement subcomponent C1q
... Hageman factor (HF, Factor XII) is activated by glass, collagen, and ellagic acid, and initiates blood coagulation via the intrinsic ...was increased. C1q reduced the activation of HF by ... See full document
7
Increased Fluidity of Human Platelet Membranes during Complement Mediated Immune Platelet Injury
... release). Complement damage to platelets was accompanied by a 10-15% increase in ΔE, the fusion activation energy for microviscosity, indicating that complement not only decreased membrane ... See full document
9
Relationship between decay accelerating factor deficiency, diminished acetylcholinesterase activity, and defective terminal complement pathway restriction in paroxysmal nocturnal hemoglobinuria erythrocytes
... their complement sensitivity, DAF reconstitution of PNH III erythrocytes restored their ability to circumvent C3b uptake but had no effect on their heightened susceptibility to reactive ...of ... See full document
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