[PDF] Top 20 Tsg101 Interacts with Herpes Simplex Virus 1 VP1/2 and Is a Substrate of VP1/2 Ubiquitin-Specific Protease Domain Activity
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Tsg101 Interacts with Herpes Simplex Virus 1 VP1/2 and Is a Substrate of VP1/2 Ubiquitin-Specific Protease Domain Activity
... 4. In Fig. 3B, the “tubulin” blot in panel B was copied and pasted from the last three lanes of the “tubulin” blot of panel A and rotated 180 degrees. 5. In Fig. 3C, in the area above the bands in the right panel of the ... See full document
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Autocatalytic Activity of the Ubiquitin-Specific Protease Domain of Herpes Simplex Virus 1 VP1-2
... The herpes simplex virus (HSV) tegument protein VP1-2 is essential for virus entry and ...assembly. VP1-2 also contains a highly conserved ... See full document
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Herpes Simplex Virus Type 2 UL56 Interacts with the Ubiquitin Ligase Nedd4 and Increases Its Ubiquitination
... a specific inhibitor of the ...the ubiquitin-proteasome pathway in the UL56-dependent degradation of Nedd4 by use of a ubiquiti- nation assay on infected ...degradation. Substrate phosphorylation is ... See full document
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Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Inhibits Beta Interferon Production by Deubiquitinating TRAF3
... DUB activity, was gen- erated. Luciferase activity assays and plaque assays showed that C40A HSV-1 replicated in Vero cells with little difference from WT ...of VP1/2 C65A mutant ... See full document
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Reciprocal Activities between Herpes Simplex Virus Type 1 Regulatory Protein ICP0, a Ubiquitin E3 Ligase, and Ubiquitin-Specific Protease USP7
... Herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 stimulates lytic infection and the reactivation of quiescent viral ...E3 ubiquitin ligase domain, which induces ... See full document
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Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Abrogates NF-κB Activation in DNA Sensing Signal Pathway
... To further determine the role of UL36USP in deconjugating the ubiquitination of I B␣, HFF cells were infected with WT HSV-1 or C40A mutant HSV-1, followed by transfection with ISD. The cells were harvested ... See full document
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Herpes simplex virus UL56 interacts with and regulates the Nedd4 family ubiquitin ligase Itch
... We explored the possibility that additional viral pro- teins mediated the decrease of Itch, since there was a small decrease in cells infected with UL56-deficient HSV-2. Two of three HSV-2 proteins with one ... See full document
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Impact of the Interaction between Herpes Simplex Virus Type 1 Regulatory Protein ICP0 and Ubiquitin-Specific Protease USP7 on Activation of Adeno-Associated Virus Type 2 rep Gene Expression
... the herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 in transfected cells reacti- vates rep gene expression from integrated adeno-associated virus (AAV) type 2 ... See full document
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Heptad Repeat 2 in Herpes Simplex Virus 1 gH Interacts with Heptad Repeat 1 and Is Critical for Virus Entry and Fusion
... functional domain for HSV-1 entry into the cell and for ...decreased virus infection and cell-cell fusion ...inhibited virus infection in a specific manner, although at high ... See full document
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Herpes Simplex Virus 1 Ubiquitin Ligase ICP0 Interacts with PML Isoform I and Induces Its SUMO-Independent Degradation
... for Virus Research, Glasgow, Scotland, United Kingdom Herpes simplex virus 1 (HSV-1) immediate-early protein ICP0 localizes to cellular structures known as promyelocytic leukemia ... See full document
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The Ability of Herpes Simplex Virus Type 1 Immediate-Early Protein Vmw110 To Bind to a Ubiquitin-Specific Protease Contributes to Its Roles in the Activation of Gene Expression and Stimulation of Virus Replication
... 1998 Herpes simplex virus type 1 immediate-early protein Vmw110 stimulates the onset of virus infection and is required for efficient reactivation from ...to specific ... See full document
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Proteolytic Cleavage of VP1-2 Is Required for Release of Herpes Simplex Virus 1 DNA into the Nucleus
... several protease inhibitors on the release of HSV-1 DNA. We chose protease inhibitors that were previously shown to interfere with the processes important for the HSV-1 replication cycle, more ... See full document
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Analysis of the Interaction between the Essential Herpes Simplex Virus 1 Tegument Proteins VP16 and VP1/2
... between VP1/2 and ...tween VP1/2 and VP16 is important for the efficiency/timing of viral assembly but is not essential for HSV-1 replication in cell ... See full document
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A Single Mutation Responsible for Temperature-Sensitive Entry and Assembly Defects in the VP1-2 Protein of Herpes Simplex Virus
... recombinant virus based on the KOS strain of HSV-1 and containing the UL36 gene from ...This virus exhibited both a ts phenotype at the immediate-early phase, revealed by maintained incubation at the ... See full document
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Herpes Simplex Virus 1 and 2
... This product is developed, designed and sold for research purposes only. It is not intended for human diagnostic or drug purposes or to be administered to humans unless clearly expressed for that purpose by the Food and ... See full document
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Phenotype of the herpes simplex virus type 1 protease substrate ICP35 mutant virus.
... Phenotypic analysis of AICP35 shows that (i) mutant virus growth in Vero cells was severely restricted, although small amounts of progeny virus were produced; (ii) full-length ICP35 prot[r] ... See full document
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The Major Determinant for Addition of Tegument Protein pUL48 (VP16) to Capsids in Herpes Simplex Virus Type 1 Is the Presence of the Major Tegument Protein pUL36 (VP1/2)
... In conclusion, pUL48 is a multifunctional protein that not only has a regulatory role in IE viral gene transcription but also has a structural role during assembly, where it appears to be involved in a number of ... See full document
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Identification of a Highly Conserved, Functional Nuclear Localization Signal within the N-Terminal Region of Herpes Simplex Virus Type 1 VP1-2 Tegument Protein
... of VP1-2, this does not address the question of nuclear capsid recruit- ment, and the role of the NLS could be in entry or some other aspect of assembly or ...defective VP1-2 on the tsB7 ...of ... See full document
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The product of the Herpes simplex virus 1 UL7 gene interacts with a mitochondrial protein, adenine nucleotide translocator 2
... HSV-1 UL7 was detected in the mitochondrial fraction of HSV-1-infected cells ANT proteins localized specifically in the inner mitochon- drial membrane. The result that UL7 interacts with ANT2 in ... See full document
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Herpes simplex virus 1 (HSV-1) and HSV-2 are infectious
... vaccinia virus, the known glycosylated antigens were recognized by sera from immunized humans and animals ...re- activity toward the poly-His or the HA tag cannot be used to quantify the amount of antigen ... See full document
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