[PDF] Top 20 Intravirion Processing of the Human Immunodeficiency Virus Type 1 Vif Protein by the Viral Protease May Be Correlated with Vif Function
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Intravirion Processing of the Human Immunodeficiency Virus Type 1 Vif Protein by the Viral Protease May Be Correlated with Vif Function
... of Vif-defective ...cells, virus stocks were pseudotyped with VSV-G. Virus replication was monitored over a 10-day period, and aliquots of the culture supernatants were harvested in 2-day intervals ... See full document
12
Regulation of Apobec3F and Human Immunodeficiency Virus Type 1 Vif by Vif-Cul5-ElonB/C E3 Ubiquitin Ligase
... Vif protein (30). The enzymatic activity of h-A3G, acting on the viral genome, appeared to be the major mechanism of antiviral function against HIV-1, and the viral Vif ... See full document
9
Human immunodeficiency virus type 1 (HIV-1) protein Vif inhibits the activity of HIV-1 protease in bacteria and in vitro.
... Human immunodeficiency virus type 1 (HIV-1) encodes auxiliary proteins which are not found in oncoretroviruses but which influence HIV-1 replication ...such protein ... See full document
8
Human Immunodeficiency Virus Type 1 Vif Protein Is an Integral Component of an mRNP Complex of Viral RNA and Could Be Involved in the Viral RNA Folding and Packaging Process
... acids 1 to 64, which is located in the N terminus of the Vif, contains a strong RNA binding ...from Vif protein significantly decreased the RNA binding ...of Vif harboring many positive ... See full document
10
Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes.
... 55-kDa protein in WT virions are consistent with the notion that under normal conditions much of the proteo- lytic processing of Gag precursor proteins occurs prior to or during budding (9, 11, 20, 21, 31, ... See full document
5
Association of Human Immunodeficiency Virus Type 1 Vif with RNA and Its Role in Reverse Transcription
... whether Vif has specificity for the HIV-1 genomic ...that Vif affects viral nucleic acid components to influence the initiation of reverse ...transcription. Vif of FIV has recently been ... See full document
8
Comprehensive Investigation of the Molecular Defect in vif-Deficient Human Immunodeficiency Virus Type 1 Virions
... of human immunodeficiency virus type 1 (HIV-1) in primary blood lymphocytes, certain T-cell lines (nonpermissive cells), and most likely in vivo is highly dependent on the ... See full document
11
Complementation of vif-defective human immunodeficiency virus type 1 by primate, but not nonprimate, lentivirus vif genes.
... this type have been described for both the Tat and the Rev proteins of HIV-1 and EIAV (6, 14, ...the viral specificity was shown to be determined by the interaction of the chimeric trans activator’s ... See full document
7
Identification of Dominant Negative Human Immunodeficiency Virus Type 1 Vif Mutants That Interfere with the Functional Inactivation of APOBEC3G by Virus-Encoded Vif
... of viral resistance. The realization that viral accessory proteins, such as Vif, Vpu, and Nef, are prominently involved in counteracting host defense mecha- nisms (for a review, see references 14 and ... See full document
11
Human Immunodeficiency Virus Type 1 Vif Protein Is Packaged into the Nucleoprotein Complex through an Interaction with Viral Genomic RNA
... how virus-associated Vif could regulate viral ...to viral RNA and Gag, Vif has a critical role in stabilizing viral nucleoprotein ...The function of Vif would ... See full document
14
Role of Vif in Stability of the Human Immunodeficiency Virus Type 1 Core
... for Vif function. One possibility is that Vif may affect the p55 Gag or p160 Gag-Pol precursor proteins, their interactions during virus assembly, or their processing during ... See full document
12
Role of Vif in human immunodeficiency virus type 1 reverse transcription.
... NC protein, the configuration of the RNA or DNA template, and the spatial organization of these components within the nucleoprotein ...of Vif may be incorporated into the virion core (22, 26), ... See full document
9
Human immunodeficiency virus type 1 Vif protein binds to the Pr55Gag precursor.
... of Vif was shown to be im- portant for the interaction of Vif with ...for Vif function and for Vif localization to membranes (21) were required for the binding of Vif to the Gag ... See full document
8
Partial Rescue of the Vif-Negative Phenotype of Mutant Human Immunodeficiency Virus Type 1 Strains from Nonpermissive Cells by Intravirion Reverse Transcription
... simian immunodeficiency viruses are complex ...rev, vif, nef, vpr, and vpu. The vif (virion infectivity factor) gene is required for human immunodeficiency virus type ... See full document
9
Cellular and Viral Specificities of Human Immunodeficiency Virus Type 1 Vif Protein
... HIV-1 Vif coun- teracts a cellular inhibitor that occurs specifically in nonper- missive human cells (22, 32), the current data strongly indicate that this increases the infectivity of HIV-1 ... See full document
6
Further Investigation of Simian Immunodeficiency Virus Vif Function in Human Cells
... lentivirus Vif proteins function by suppressing the antiviral activity of the cell-encoded apolipopro- tein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC) proteins APOBEC3G and ...to Vif ... See full document
6
Mutational Analysis of the Human Immunodeficiency Virus Type 1 Vif Protein
... example, human immunodeficiency virus type 1 (HIV-1) encodes six accessory/regulatory genes in addition to the struc- tural and enzymatic gag, pol, and env genes that are present ... See full document
7
Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.
... The vif open reading frame, encoding a protein of approxi- mately 23 kDa, is conserved among all primate lentiviruses, including HIV-1, HIV-2 (14, 18, 29), and SIV (3), as well as nonprimate ... See full document
5
Characterization of human immunodeficiency virus type 1 Vif particle incorporation.
... of Vif protein in HIV-1 particles. vif-competent (R7) and vif-defective ( D Vif) particles produced by CEM cells and normalized by ELISA for p24 CA content were analyzed by ... See full document
6
Phenotypically Vif- human immunodeficiency virus type 1 is produced by chronically infected restrictive cells.
... the human immunodeficiency virus type 1 (HIV-1) genome con- tains several smaller regulatory or accessory genes ...The vif gene has been shown to be essential in ... See full document
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