[PDF] Top 20 Involvement of human papillomavirus type 8 genes E6 and E7 in transformation and replication.
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Involvement of human papillomavirus type 8 genes E6 and E7 in transformation and replication.
... After transfection of C127 cells, 14 G418-resistant lines were established and the presence of the E6 mutant construct was confirmed by Southern blot hybridization Downloaded from http:/[r] ... See full document
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Evidence for Alteration of EZH2, BMI1, and KDM6A and Epigenetic Reprogramming in Human Papillomavirus Type 16 E6/E7-Expressing Keratinocytes
... in E6/E7 cells, we examined the expres- sion of known EZH2-, KDM6A-, and BMI1-targeted HOX genes in vitro (1, 4, 8, 23, 32, 46), including HOXC5 and -C8, which have been shown to be ... See full document
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Genetic variability in E6 and E7 oncogenes of human papillomavirus Type 16 from Congolese cervical cancer isolates
... the E6 and E7 genes using type-specific primers PCR and direct ...in E6 and E7 genomic regions ...in E6 (100%), leading to the non-synonymous amino acid variation Q14D and ... See full document
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Human Papillomavirus Type 16 Variant Analysis of E6, E7, and L1 Genes and Long Control Region in Identification of Cervical Carcinomas in Patients in Northeast China
... 16 E6 may have effects (2, 13, ...6, 8, 9, 19, 47, ...at E7 displays geographic dependence (14, 36). The E7 N29S replacement may be associated with a higher oncogenic risk (12, 23, ... See full document
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Myc and Human Papillomavirus Type 16 E7 Genes Cooperate To Immortalize Human Keratinocytes
... of E7 (Fig. 2B) due to the known ability of E7 to facilitate the degradation of pRb ...why E7 is required to be expressed si- multaneously with Myc for cell ...⫹ E7 cells) can bind and disrupt ... See full document
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Down Regulation of the Interleukin-8 Promoter by Human Papillomavirus Type 16 E6 and E7 through Effects on CREB Binding Protein/p300 and P/CAF
... that human papillomavirus (HPV) type 16 E6 binds to C/H1, C/H3, and the C-terminal domains of coactivators p300 and CBP, causing the modulation of the transcription of certain genes ... See full document
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Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription
... in E6, E7, or both (see Materials and ...assorted E6/E7 ...of E6 and E7 ...either E6 or E7, there is an activation of IIG expression, not a ...between E6 and ... See full document
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RNA (E6 and E7) Assays versus DNA (E6 and E7) Assays for Risk Evaluation for Women Infected with Human Papillomavirus
... the E6 and E7 viral onco- genes. E6 and E7 viral oncoproteins bind and modulate cellu- lar gene products (p53 and pRb) that play a key role in cell cycle control and DNA ...cell ... See full document
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Negative regulation of the bovine papillomavirus E5, E6, and E7 oncogenes by the viral E1 and E2 genes.
... the papillomavirus life cycle, and in some systems has been shown to be essential for production of epitheliomas ...that papillomavirus oncogenes are subject to negative ...benign ... See full document
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THE CARCINOGENIC POTENTIAL OF E6 & E7 GENES OF HIGH RISK HPV COMPARED WITH E6, E7 GENES OF LOW RISK HPV IN HUMAN CERVICAL CANCER: A REVIEW
... the human papilloma virus 4, 5 ...with type 16 accounting for about half of the cases in the United States and Europe and types 18, 31, and 45 accounting for an additional 25 to 30% of cases 6 ... See full document
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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.
... 4417-4421 0022-538X/89/104417-05$02.00/0 Copyright ©3 1989, American Society for Microbiology NOTES The E6 and E7 Genes of the Human Papillomavirus Type 16 Together Are Necessary and Suf[r] ... See full document
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The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells.
... p18-1.5 encodes all viral early genes, while p18PE encodes 3635 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Plasmids containing the E6 and E7 open reading frames of[r] ... See full document
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The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells.
... Studies of human cell transformation have shown that HPV16 and HPV18 DNA immortalized primary human epithelial cells, whereas HPV6 and HPV11 DNA did not 26, 38, 40, 45, 54.. The immortal[r] ... See full document
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Involvement of Nuclear Export in Human Papillomavirus Type 18 E6-Mediated Ubiquitination and Degradation of p53
... Ubiquitination assays. The p53 ubiquitination assays were performed essen- tially as previously described (18). Briefly, H1299 cells were cotransfected with p53 or p53(NES-) expression vectors and either control pCDNA3, ... See full document
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Targeting the Human Papillomavirus E6 and E7 Oncogenes through Expression of the Bovine Papillomavirus Type 1 E2 Protein Stimulates Cellular Motility
... HPV E6/E7 stimulates migration in HPV-positive cancer ...HPV E7 levels and increased p53 ...primary human foreskin keratinocytes did not show an increase in migration upon AdE2ts ... See full document
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Open reading frames E6 and E7 of bovine papillomavirus type 1 are both required for full transformation of mouse C127 cells.
... * 259 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest A series of mutations in open reading frames ORFs E6 and E7 of bovine papillomavirus type 1 BPV1 was constructed t[r] ... See full document
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CCAAT Displacement Protein Binds to and Negatively Regulates Human Papillomavirus Type 6 E6, E7, and E1 Promoters
... least one case (CDP-b), full binding activity required se- quences that overlap a previously identified binding site (CDP- a). Within the human tryptophan hydroxylase (hTPH) regula- tory region, there are two ... See full document
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Skin Hyperproliferation and Susceptibility to Chemical Carcinogenesis in Transgenic Mice Expressing E6 and E7 of Human Papillomavirus Type 38
... epitheliotropic human papillomaviruses may cooperate with UV in the development of NMSC ...The involvement of an infective agent in skin carcinogenesis is supported by the fact that immunosuppressed organ ... See full document
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Inhibition of growth, transformation, and expression of human papillomavirus type 16 E7 in human keratinocytes by alpha interferons.
... 3396 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest We used a model system of normal human keratinocytes HKc and HKc immortalized with human papillomavirus type 16 DNA [r] ... See full document
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Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus type 16.
... American Type Culture Collection (Rockville, ...the E7 gene of HPV-16 has been described elsewhere ...HPV-16 E7 message, and clone EL4E7, which stably expresses the E7 gene, was selected for ... See full document
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