[PDF] Top 20 Krüppel like factors in mammalian stem cells and development
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Krüppel like factors in mammalian stem cells and development
... chondrogenic cells, independent of iPSCs, for cartilage regeneration has been previously proposed (Hiramatsu et ...multipotent stem cells express Klf4 and that deletion of Klf4 reduces the ... See full document
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Krüppel-like factors: Three fingers in control
... Kru¨ppel-like factors (KLFs), members of the zinc-finger family of transcription factors capable of binding GC-rich sequences, have emerged as critical regulators of important functions all over the ... See full document
8
Krüppel-like family of transcription factors: an emerging new frontier in fat biology
... growth, development and reproduction of most animals, thus any abnormalities caused by excess fat accumulation can result in pathological conditions which are linked to several interrelated diseases, such as ... See full document
15
The Janus-faced roles of Krüppel-like factor 4 in oral squamous cell carcinoma cells
... post-mitotic cells in both gut and skin ...in development and in the maintenance of normal tissue homeostasis [6, ...in stem cell renewal and in the maintenance of pluripotency [8, ... See full document
15
Oct transcription factors in development and stem cells: insights and mechanisms
... domain-containing factors, five of which are clear Oct protein orthologs (Table ...POU2 factors should not be confused with POU class II transcription ...and mammalian Oct4 are related to each other ... See full document
10
New insights into mechanisms that regulate DNA methylation patterning
... embryonic cells and a stepwise acquisition of information gradually restricts this potency and establishes epigenetic barriers to avoid transition from one state to ...transcription factors will be able to ... See full document
7
Commitment of hematopoietic stem cells in avian and mammalian embryos: an ongoing story
... of cells available small, making the classical in vitro clonal culture technology appropriate (review by Godin and Cumano, 2005 in this ...single cells and seeded on a feeder layer of growth factor ... See full document
6
Acute myeloid leukemia and transcription factors: role of erythroid Krüppel-like factor (EKLF)
... erythroid cells and megakaryocytes [4]. GATA1-null cells stall at the pro- erythroblast stage, after which they readily undergo apoptosis ...hematopoietic stem cell and progenitor cell compartments ... See full document
13
Targeted DamID reveals differential binding of mammalian pluripotency factors
... homogeneous cells and antisera with high ...in mammalian systems, generating an inducible system (mammalian TaDa or MaTaDa) to identify genome-wide protein/DNA interactions in 100 to 1000 times fewer ... See full document
11
Krüppel like factor 4 regulates macrophage polarization
... proinflammatory factors. M1 macrophages are critical effector cells that kill microorganisms and thus benefit the ...the development of obesity and insulin resistance (1, ...the development of ... See full document
15
The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells
... Given the emerging evidence that common environmental carcinogens play a significant role in cancer [1], increased attention has been paid to molecular mechanisms through which pollutants affect tumor formation, invasion ... See full document
22
The Specificity Protein 2 (Sp2) in the Proliferation and Cell Cycle Progression of the Neural Progenitors.
... transcription factors has been associated with progenitor functions including regulation of the cell cycle (Baur et ...embryonic development in mice and zebrafish (Baur et ...skin stem cell and ... See full document
157
Overlapping functions of Krüppel like factor family members: targeting multiple transcription factors to maintain the naïve pluripotency of mouse embryonic stem cells
... these cells the expression of KLF17 is high, whereas the expression of KLF2 – which has a significant role in the maintenance of pluripotency in naïve mESCs – is low (Blakeley et ... See full document
12
Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cells
... iHep cells were transplanted into CCL4 liver injured mice and it was observed that iHeps not only could improve liver function but also restored the injured ...differentiated cells can improve liver injury ... See full document
14
Embryonic stem cell differentiation and the analysis of mammalian development
... EPL cells can be induced by differentiation within an ES cell EB environment, the potent neural inducer retinoic acid or supplementation of the differentiation environment with MEDII (Lake et ...EPL cells ... See full document
10
Identification and characterization of epithelial cells derived from human ovarian follicular fluid
... Epithelial cells cultured for 1 week, epithelial cells cul- tured for 1 month, the human skin fibroblast cell line (purchased from Cell bank of China, Shanghai, China) and human ovarian cortex were ... See full document
13
Mesenchymal stem cell-based cell-free strategies: safe and effective treatments for liver injury
... NTA determines the number and size of particles by tracking the Brownian motion of single particles in an aqueous solution [66]. Quantification of EVs remains ex- tremely challenging, and new methods, such as nanoflow ... See full document
12
Human adult dental pulp CD117/c-kit-positive networks of stromal cells
... undifferentiated cells migrate to various zones where they can differentiate under different conditions and make new differentiated cells and tissues ...that cells committed to odontoblastic ... See full document
5
Knockdown of KLF5 suppresses hypoxia induced resistance to cisplatin in NSCLC cells by regulating HIF 1α dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway
... the development of chemotherapy resistance and inhibition of the PI3K/Akt/mTOR path- way reverses drug resistance in several tumors [44, ...osteosarcoma cells through activa- tion of the PI3K/Akt pathway ... See full document
10
Stem cells and transgenic mice in the study of development
... Int J Dn BinI 37 89 99 (1993) 89 SPecial Review Stem cells and transgenic mice in the study of development' RALPH L BRINSTER* School of Veterinary Medicine, University of Pennsylvania Philadelphia, US[.] ... See full document
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