[PDF] Top 20 Long non-coding RNAs as novel players in β cell function and type 1 diabetes
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Long non-coding RNAs as novel players in β cell function and type 1 diabetes
... important players in mediating enhancer function ...tein coding and non-coding genes in both cis and trans mediated ...over long distances by long range chromatin loop ... See full document
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Identification of novel long non-coding RNAs in triple-negative breast cancer
... To predict the functions of the lncRNAs, we adopted method originally demonstrated in this paper[10]. Briefly, we first calculated the co-expressed mRNAs for each of the differentiated lncRNAs, and then we conducted a ... See full document
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Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer
... Visual inspection of these results confirmed that similar PCa-specific expression patterns occurred in all three datasets with TCs grouped into one EPCAT following the same PCa-specific outlier profile (see Figure 3 and ... See full document
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Single cell analysis of long non coding RNAs in the developing human neocortex
... file 1: Table ...as novel transcripts ...transcripts novel as compared with Ensembl, we utilized Cuffcompare class codes and extracted those assembled transcripts classified as: i – novel ... See full document
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The function of non coding RNAs in genomic imprinting
... Box 1) and genome-wide cDNA sequencing have shown not only that most of the mammalian genome is transcribed, but also that the majority of the mammalian transcriptome consists of non-coding (nc) ... See full document
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Abstract: Long non-coding RNAs (lncRNAs) are a novel class of regulatory RNA molecules and they
... transcript 1 (MALAT1) [51–60], maternally expressed 3 (MEG3) [61–68], taurine up-regulated 1 (TUG1) [69–71], plasmacytoma variant translocation 1 (PVT1) [72,73], ANRIL (CDKN2B-AS1) [74,75], HOTAIR ... See full document
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Long non-coding RNAs in ovarian cancer
... neighboring coding gene functions of up-regulated lncRNAs were primarily in- volved in the mitotic cell cycle, mitotic nuclear division, and the cell cycle, the neighboring coding gene ... See full document
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<p>LncRNA <em>TBX5-AS1</em> Regulates the Tumor Progression Through the PI3K/AKT Pathway in Non-Small Cell Lung Cancer</p>
... Long non-coding RNAs (lncRNAs) are increasingly implicated as gene regulators in diverse ...a novel tumor suppressor gene in the disease ...RNA 1 (TBX5- AS1), a newly discovered ... See full document
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Original Article Potentials of long non-coding RNAs to differentiate latent autoimmune diabetes in adults from type 2 diabetes
... incubated cell pellets with 40 μL of proteinase K and a mixture of 300 μL of binding buffer for 10 min at 55 °C while being ...for 1 min at 16300 ... See full document
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Long non-coding RNAs in normal and malignant hematopoiesis
... transcript 1 (MALAT1) is a putative oncogenic lncRNA of more than 8000 nt transcribed from chromosome ...and cell cycle has been proposed for this lncRNA ...involving cell cycle regulation, ... See full document
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Long non-coding RNAs in the regulation of myeloid cells
... that diabetes promotes the polarization of macrophages into M2, which is a pro-inflammatory, pro-fibrotic, and dys- functional alternatively activated macrophage phenotype, through TFs associated with macrophage ... See full document
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Role of Long Non coding RNAs in Sculpting Neurons
... from cell to ...other cell types like muscle ...of cell shape and its relation to the function of the neuron (Cajal, ...main cell body or soma of the neuron contains the nucleus and is ... See full document
8
An overview of long non-coding RNAs in ovarian cancers
... inhibit cell proliferation in the absence of p53 underlines its tumor suppressor activity ...and cell lines. Its re-expression decreased OVCAR3 cell line growth and proliferation ...wild type ... See full document
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The functional role of long non-coding RNAs and epigenetics
... accompany cell type-specific epigenetic alterations of the ...specific cell type to ...in cell fate decision ...(HOTAIR long ncRNA) is able to promote cancer metastasis by ... See full document
13
Linking a role of lncRNAs (long non-coding RNAs) with insulin resistance, accelerated senescence, and inflammation in patients with type 2 diabetes
... to type 2 diabetes mellitus (T2DM) at the genomic ...of long non-coding RNAs ...with type 2 diabetes (T2DM; n = 30) compared to individuals with normal glucose ... See full document
9
Circular RNAs: A novel type of non-coding RNA and their potential implications in antiviral immunity
... The function analyses of these circRNAs demonstrate that they mainly participate in the cellular pathways that are associated with viral entry, replication as well as ...the function of host circRNAs in ... See full document
10
Novel classes of non coding RNAs and cancer
... fering RNAs (siRNAs). They are produced from long dsRNAs of exogenous or endogenous origin ...retarding cell division by interfering with cyclins and related genes or enhancing apoptosis by ... See full document
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<p>Roles of Wnt/β-Catenin Signaling Pathway Regulatory Long Non-Coding RNAs in the Pathogenesis of Non-Small Cell Lung Cancer</p>
... Wnt/ β -catenin pathway. 65 The oncogenic urothelial carci- noma associated 1 (UCA1) increases the expression of Wnt-3a, Wnt-5a and β -catenin proteins, thereby stimulat- ing Wnt signaling activity ... See full document
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The roles of lncRNA in hepatic fibrosis
... that long non‑coding RNAs (lncRNAs) regulate gene or protein expression; however, their function in the progression of hepatic fibrosis remains ...transcript 1 (MALAT1) and liver ... See full document
8
Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma
... discover novel ABC- or GCB-specific lncRNAs and identified 465 such lncRNAs (FDR ...hclust function in R) of the primary tumor samples, confirmed the pattern of subtype specific gene expression for these ... See full document
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