[PDF] Top 20 Membrane anchoring domain of herpes simplex virus glycoprotein gB is sufficient for nuclear envelope localization.
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Membrane anchoring domain of herpes simplex virus glycoprotein gB is sufficient for nuclear envelope localization.
... 68, 1994 NUCLEAR ENVELOPE LOCALIZATION SIGNAL OF gB-1 mutant gB-1 proteins containing shortened cytoplasmic tails or deletions in the predicted hydrophobic membrane anchoring domain as w[r] ... See full document
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The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K (gK) Is Required for gB Binding to Akt, Release of Intracellular Calcium, and Fusion of the Viral Envelope with Plasma Membranes
... PH domain of Akt and blocks the recruitment of Akt to the inner leaflet of the plasma membrane ...and virus entry experiments were performed as described in Materials and ...on virus entry was ... See full document
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The Transmembrane Domain and Cytoplasmic Tail of Herpes Simplex Virus Type 1 Glycoprotein H Play a Role in Membrane Fusion
... Herpes simplex virus glycoprotein H (gH) is one of the four virion envelope proteins which are required for virus entry and for cell-cell fusion in a transient ...in ... See full document
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Effects of Phosphorylation of Herpes Simplex Virus 1 Envelope Glycoprotein B by Us3 Kinase In Vivo and In Vitro
... of gB, which appears to downregulate cell surface expression of gB ...in gB (gB-T887A) markedly upregulated cell surface expression of gB in infected cells: this upregulation was also ... See full document
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Membrane Requirement for Folding of the Herpes Simplex Virus 1 gB Cytodomain Suggests a Unique Mechanism of Fusion Regulation
... Herpes simplex virus type 1 (HSV-1) enters cells by fusion of its envelope with a host cell membrane, which requires four viral glycoproteins and a cellular ...fusion ... See full document
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Multiple Roles of the Cytoplasmic Domain of Herpes Simplex Virus 1 Envelope Glycoprotein D in Infected Cells
... plasma membrane, but at significantly levels lower than the levels at which they were induced by expression of wild-type gD-EGFP ...subcellular localization in infected cells and on virion incorporation of ... See full document
12
Intragenic and Extragenic Suppression of a Mutation in Herpes Simplex Virus 1 UL34 That Affects both Nuclear Envelope Targeting and Membrane Budding
... and sufficient for an interaction with pUL31 that leads to NE targeting of the pUL31/pUL34 complex ...UL34-null virus in trans, suggesting that an essential function of pUL34 had been ...NE ... See full document
11
The Extracellular Domain of Herpes Simplex Virus gE Is Sufficient for Accumulation at Cell Junctions but Not for Cell-to-Cell Spread
... Herpes simplex virus (HSV) expresses a number of membrane glycoproteins, including gB, gD, and gH/gL, that function in both entry of virus particles and movement of virus ... See full document
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Herpes Simplex Virus Type 1 Glycoprotein E Is Required for Axonal Localization of Capsid, Tegument, and Membrane Glycoproteins
... of gB, gC, gD, and gE ...NS-gEnull virus, based on immuno- fluorescence staining of retinas at 3 and 5 dpi ...pseudotype virus to verify that the increase in infection by WT and gE-null viruses on ... See full document
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Effects of deletions in the carboxy-terminal hydrophobic region of herpes simplex virus glycoprotein gB on intracellular transport and membrane anchoring.
... Thus, although these mutants are defective in intracellular transport to the Golgi complex or the cell surface, they form dimers and are transported to the nuclear envelope in a manner s[r] ... See full document
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Exploring the Nuclear Envelope of Herpes Simplex Virus 1-Infected Cells by High-Resolution Microscopy
... empty nuclear pores at the inner nuclear ...and nuclear membranes were removed, giving a clear view onto the nuclear pore com- ...enlarged nuclear pore com- plexes with an enlarged ... See full document
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Identification of nuclear and nucleolar localization signals in the herpes simplex virus regulatory protein ICP27.
... The molecular mechanisms by which ICP27 carries out its lytic functions have not yet been defined. However, several recent studies suggest that ICP27 may work, at least in part, through posttranscriptional gene ... See full document
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Baculovirus gp64 envelope glycoprotein is sufficient to mediate pH-dependent membrane fusion.
... These studies provide direct evidence that gp64 is a pH-dependent membrane fusion protein and suggest that gp64 is the protein responsible for fusion of the virion envelope with the endo[r] ... See full document
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Expression of cell-associated and secreted forms of herpes simplex virus type 1 glycoprotein gB in mammalian cells.
... To establish permanent CHO cell lines expressing either a membrane-bound or secreted form of gBl, portions of the gBl gene from HSV-1 strain Patton were inserted into an expression vecto[r] ... See full document
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Mechanism of Neutralization of Herpes Simplex Virus by Antibodies Directed at the Fusion Domain of Glycoprotein B
... the gB-liposome association by IgGs ...of gB to lipo- somes via biosensor analysis (27) to now measure the association of gB with liposomes in the presence of anti-gB IgGs or ...and ... See full document
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Mechanism of Neutralization of Herpes Simplex Virus by Antibodies Directed at the Fusion Domain of Glycoprotein B
... the gB-liposome association by IgGs ...of gB to lipo- somes via biosensor analysis (27) to now measure the association of gB with liposomes in the presence of anti-gB IgGs or ...and ... See full document
13
Mutations in the membrane-spanning domain of the human immunodeficiency virus envelope glycoprotein that affect fusion activity.
... Subsequent mutagenic analysis of the HIV-1 Env transmembrane domain revealed that the sequence of amino acid residues from positions 696 to 707 of the transmembrane domain was important [r] ... See full document
5
A retention signal necessary and sufficient for Golgi localization maps to the cytoplasmic tail of a Bunyaviridae (Uukuniemi virus) membrane glycoprotein.
... rubella virus also bud into the Golgi complex or the ER-Golgi intermediate ...M membrane glycoprotein seems to determine the site of bud- ...three membrane-spanning domains is essential for ... See full document
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The Membrane Proximal Region (MPR) of Herpes Simplex Virus gB Regulates Association of the Fusion Loops with Lipid Membranes
... restores gB-liposome binding. Be- cause mutants such as gB-W174R(730t) do not bind liposomes ...of gB(730t) with lipid membranes occurs via its fusion loops ...are sufficient to reduce this ... See full document
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Early, Active, and Specific Localization of Herpes Simplex Virus Type 1 gM to Nuclear Membranes
... of nuclear exit site where gM would assume a scaffolding ...as nuclear gM does not overlap with the major capsid protein at these early times (data not ...maintain nuclear in- vaginations in an ... See full document
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