[PDF] Top 20 MET expression during prostate cancer progression

... protein expression was observed in pre- existent basal and atrophic luminal glandular epithelium, which served as internal positive controls, and was variably expressed in both normal and tumor-associated ... See full document

... BIRC5 expression in RasB1 cells transfected with an empty vector (EV)/miR-34a precursor or control/ anti-miR-34a ...mRNA expression was normalized to ...transient expression of an empty vector ... See full document

... Src kinase is a nonreceptor kinase of considerable importance in prostate cancer progression. Src, an essential downstream signal transducer for many cell surface receptors, including epidermal ... See full document

... constitutive expression of HIF, as shown by a shift from epithelial to mesenchymal markers and an increase in the ability of migration and invasion ...E-cadherin expression, a very important caretaker of ... See full document

... The expression rate of PSCA in prostate cancer tissue is almost 90%, much higher than that in normal prostate ...of prostate cancer, PSCA expression level in cancerous ... See full document

... Gene expression signatures were derived from dif- ferentially expressed genes among ERG-fusion, SPOP-mutant, and all tumors, as compared with normal samples, by using the Wilcox- on signed-rank test after ... See full document

... lung cancer [18], breast can- cer [19, 20], colorectal cancer [21], oral cancer [22], melanoma [23] and brain gliosarcoma ...in prostate cancer is still not ...cortactin ... See full document

... The finding that NE tumors can no longer develop in the absence of Siah, combined with observation of reduced HIF-1 α expression, led us to explore the possibility that HIF-1 α activity is required for the ... See full document

... to cancer cell viability and aggressive phenotype through functional linking between the PKA and Akt pathways [28] PKIB is overexpressed in aggressive castration-resistant PCa and its overexpression correlates ... See full document

... malignant prostate tissue ( n = ...the prostate tumor, 5 of adjacent benign tissue and 5 of distant metastatic ...regulating progression of PCa, where the miR-128 levels were elevated in lines of BPH ... See full document

... Prostate cancer is one of the most common malignancies and the leading cause of cancer- related death in men worldwide ...metastatic prostate cancer that has failed to respond to ... See full document

... normal prostate tissue expresses a high level of EphA7, which is progressively lost during CaP development ...of prostate cancer ...the expression profile of all currently known human ... See full document

... resistant tumor-bearing Pten ⫺/⫺ mice at 3 and 6 months of age. The culture method was a modification of that described by Nandi et al. for primary cultures of mouse mammary epithelium (33) modified for pros- tate ... See full document

... different prostate cell types are necessary to resolve this debate over the cell of origin of prostate ...for prostate epithelial cell growth; (b) identification of PSCs and epithelial lineage  ... See full document

... The QRFP is a member of RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (Crawford). QRFP exerts its functional effects through ... See full document

... in cancer cells, with specific alterations in various aspects of lipid metabolism being seen [34, ...breast cancer cells, MORC2 promotes ACLY activation, giving MORC2 a role in lipogenesis ...tered ... See full document

... patients with a Gleason score of 8-10 have the highest amount of TNF-Alpha, followed by those with a Gleason score of 5-7, then those with a Gleason score of 2-4. The levels of TNF-Alpha among the BPE patients were less ... See full document

... advanced prostate cancer, but most patients eventually progress to castra- tion-resistant prostate cancer within 2–3 years, which is a lethal stage of the ...tion-resistant prostate ... See full document

... fresh prostate cancer and adjacent normal tissues were extracted by radio- immunoprecipitation assay (RIPA) buffer containing 1 mM phenylmethanesulfonyl fluoride (PMSF) (Beyotime, Haimen, ... See full document

... tumor progression is not entirely ...cervical cancer have shown that TSPAN1 can promote tumor cell proliferation and invasion in vitro and its expression is elevated in these primary tumor tissues of ... See full document