[PDF] Top 20 Microbiologic factors affecting Clostridium difficile recurrence
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Microbiologic factors affecting Clostridium difficile recurrence
... Relapse versus reinfection: recurrent Clostridium difficile infection following treatment with fidaxomicin or vancomycin.. Richardson C, Kim P, Lee C, Bersenas A, Weese JS.[r] ... See full document
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Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: a retrospective cohort study
... risk factors for CDI recurrence ...other factors, including iCDI treatment and specific non-CDI antimi- crobials, could not be evaluated adequately due to the lack of robust ...the factors ... See full document
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Predictors of first recurrence of clostridium difficile infection: Implications for initial management
... of recurrence over time was estimated using competing risks methods to account for death before ...daily recurrence risk varied with time from fi rst CDI ...of factors theoretically available at ... See full document
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Factors affecting development of Clostridium difficile infection in hospitalized pediatric patients in the country Georgia
... C. difficile (25%), but also may be caused directly by osmotic imbalances in the intestines due to antibiotic exposure and disruption of normal bacterial ... See full document
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A Modified R Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota Diversity
... of recurrence (2, 3, 6, 41), a stand-alone anti-RT027 agent, such as ...C. difficile prophage RBP provides a template for their ...C. difficile population and genome min- ing of intended target ... See full document
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Predicting recurrence of Clostridium difficile infection following encapsulated fecal microbiota transplantation
... CDI recurrence were subsequently retreated by cap-FMT, received colonoscopic FMT, or remained on a long-term suppressive treatment with a daily dose of ...these factors were shown to be significantly ... See full document
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Comparative Analysis of Prevalence, Risk Factors, and Molecular Epidemiology of Antibiotic Associated Diarrhea Due to Clostridium difficile, Clostridium perfringens, and Staphylococcus aureus
... C. difficile cytotoxin, ...risk factors associated with these causes of infective AAD but not neces- sarily with nosocomial diarrhea per se ...risk factors associ- ated with nosocomial ...risk ... See full document
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Clinical and microbiologic characteristics of tcdA negative variant clostridium difficile infections
... [14]. Recurrence was defined as growth of toxinogenic C. difficile, a posi- tive A&B toxin assay (VIDAS ® ...C. difficile Toxins A & B; BioMerieux SA, Marcy l’Etoile, France), or a pseudo- ... See full document
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Bezlotoxumab for the prevention of <em>Clostridium difficile</em> infection: a review of current evidence and safety profile
... CDI recurrence within 28 days of completion of fidaxomicin or ...CDI recurrence, even after controlling for factors linked to recurrence such as age, type of antibiotic treatment, concomitant ... See full document
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Risk factors, course and outcome of Clostridium difficile infections
... C. difficile, were randomly assigned to receive vancomycin, 125 mg, 4 times daily or fidaxomicin, 200 mg, twice daily for 10 .... Recurrence of CDI (using the same criteria as for enrollment [ie, ... See full document
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Toxin Synthesis by Clostridium difficile Is Regulated through Quorum Signaling
... C. difficile regulation of toxin synthesis and pathogenesis. Several factors, such as nutrients, amino acids, and antibiotics, have been suggested to play a role in ...C. difficile toxin synthesis, ... See full document
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Function of the CRISPR Cas System of the Human Pathogen Clostridium difficile
... C. difficile CRISPR ...C. difficile CRISPR spacers and the targeted ...C. difficile strain 630 CRISPR repeat consensus sequence in comparison with other CRISPR-Cas I-B ...C. difficile strain ... See full document
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Intrinsic Toxin Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB
... T cdB is an intracellular bacterial toxin produced by the spore-forming, anaerobic, human pathogen Clostridium difficile (1). This 2,366-amino-acid (aa) protein binds to cell surface receptors (CSPG4, PVRL3, and ... See full document
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Retrospective analysis of Clostridium difficile infection in patients with ulcerative colitis in a tertiary hospital in China
... risk factors for CDI in patients with UC are different from those of non-UC ...matched factors and were excluded from the analysis, which could also have excluded relevant ...ing factors, ... See full document
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False Negative Results in Clostridium difficile Testing
... C. difficile , repeated testing or testing as a proof of cure is usually not ...C. difficile isolated from these patients have consistently produced the same ribo- ...C. difficile of the same ... See full document
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A Clostridium difficile Specific, Gel Forming Protein Required for Optimal Spore Germination
... In the model organism Bacillus subtilis, the order of cortex hydrolysis and CaDPA release is reversed: germinant binding induces CaDPA release, and CaDPA directly activates the cortex hydrolase CwlJ (16). While there is ... See full document
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Recurrence of dual-strain Clostridium difficile infection in an in vitro human gut model
... difficile remained as spores until total counts began to increase relative to 218 spore counts, 9 and 11 days after vancomycin cessation for strains CD-RM and CD-CR, 219 respectively.. T[r] ... See full document
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Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficileinfection in mice following vancomycin treatment
... . difficile strain VPI10463 was purchased from American Type Culture Collection (Manassas, ...for Clostridium difficile growth was pur- chased from Anaerobe Systems (Morgan Hill, .... ... See full document
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Inflammasome Activation Contributes to Interleukin 23 Production in Response to Clostridium difficile
... C. difficile bacte- rial burden does not ...transcription factors NF- B and AP-1 downstream of TLR and IL-1 receptor signaling (20), leading us to hypothesize that ...C. difficile may be able to ... See full document
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Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections
... Comparison of epidemiology of pediatric and adult CDI: While the overall median incidence from Table 1 of pediatric CDI (31/10000) may be higher than adult CDI (10/10000), these rates are highly influenced by method in ... See full document
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