[PDF] Top 20 Mitochondrial Dysfunction in Lyssavirus-Induced Apoptosis
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Mitochondrial Dysfunction in Lyssavirus-Induced Apoptosis
... major mitochondrial import signal remains between residues 46 and 110 and consequently is in- dependent of the late viral budding domain, located between positions 1 and 48 of M ...putative mitochondrial ... See full document
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Mitochondrial dysfunction in diabetic cardiomyopathy
... of mitochondrial fi ssion and fusion. Thus, the change in mitochondrial number in diabetic hearts may re fl ect alterations in rates of mitochondrial fi ssion and/or ...addition, mitochondrial fi ... See full document
9
Neuronal degeneration and mitochondrial dysfunction
... cyanide- induced depolarization of mitochondria, as well as a greater vulnerability to staurosporin, an inducer of mito- chondrion-mediated ...similar mitochondrial defects (35). Despite evidence in support ... See full document
11
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction
... the apoptosis (pan- caspase) inhibitor Z-VAD-FMK, or the RIPK1-specific necroptosis inhibitor ...the apoptosis inhibitor and the necroptosis inhibitor markedly decreased LPS-induced cell death as ... See full document
18
A novel cytoprotective peptide protects mesenchymal stem cells against mitochondrial dysfunction and apoptosis induced by starvation via Nrf2/Sirt3/FoxO3a pathway
... Scientific community has paid much attention to improve the viability of MSCs in response to nutrient deprivation. Treatment of various reagents is considered as a feasible procedure to protect MSCs from starvation. ... See full document
13
Transient receptor potential ankyrin 1 (trpa1) mediates il-1β-induced apoptosis in rat chondrocytes via calcium overload and mitochondrial dysfunction
... cell apoptosis may require future research which is be- yond the scope of the current ...of mitochondrial pro-apoptotic proteins including BAX, cytochrome c, PARP, caspase-3 and ...of mitochondrial ... See full document
9
Polyphyllin VII induces apoptosis in HepG2 cells through ROS mediated mitochondrial dysfunction and MAPK pathways
... contrast, apoptosis, a programmed cell death, is usually a physiological event that does not provoke inflammation ...Therefore, apoptosis was con- sidered a potent therapeutic target for cancer treatment to ... See full document
12
Bax Is Activated during Rotavirus-Induced Apoptosis through the Mitochondrial Pathway
... rotavirus-induced apoptosis, and indeed, the intracellular calcium ion chelator BAPTA-AM partially inhibits apoptosis ...induces apoptosis by inducing both ER stress and ER Ca 2⫹ depletion, ... See full document
8
Enriched endoplasmic reticulum-mitochondria interactions result in mitochondrial dysfunction and apoptosis in oocytes from obese mice
... Results: First, oocytes from mice with high-fat-diet (HFD)-induced obesity had higher levels (either greater numbers or a higher proportion for the same numbers) of MAM than oocytes from control mice. The ... See full document
8
Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition
... cal dysfunction in mitochondria ...of mitochondrial membrane potential, which is called mitochondrial permeability transition ...causes mitochondrial swelling (17). As mitochondrial ... See full document
12
Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer
... The present study demonstrates that PL can act as a ROS inducer agent to enhance AF-induced human gastric cancer cell killing and apoptosis through ROS- mediated ER-stress and mitochondrial ... See full document
17
A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress
... cell apoptosis of JJ012 and SW1353 cell lines with half-maximal inhibitory concentration (IC50) values of ...μM) induced a dose-dependent inhibition of clonogenicity, and the quantitative results containing ... See full document
14
NLRP3 inflammasome activation is involved in Ang II-induced kidney damage via mitochondrial dysfunction
... as mitochondrial dysfunction, extracellular ATP and damaged nucleic ...part apoptosis-associated speck- like protein containing a CARD (ASC) and the effector protease caspase-1, to promote the ... See full document
13
Buyang Huanwu Decoction attenuates H2O2 induced apoptosis by inhibiting reactive oxygen species mediated mitochondrial dysfunction pathway in human umbilical vein endothelial cells
... BYHWD has been used to treat stroke and stroke- induced disability in China for centuries [33]. Recent studies have reported that BYHWD has a protective effect on nerve cells in humans and animal models [12, 34]. ... See full document
11
Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195
... Targeting to metabolic memory may provide a new strat- egy for the treatment of DR. Lots of molecular pathways are involved in the metabolic memory. Increase of the inflammatory mediators and oxidative stress are the ... See full document
17
Aeromonas hydrophila Induced Mitochondrial Dysfunction and Apoptosis in Liver and Spleen of Labeo rohita Mediated by Calcium and Reactive Oxygen Species
... of mitochondrial trans-membrane potential ...of mitochondrial function and has been used as an indicator of healthy ...during apoptosis (Green & Reed, ...during apoptosis (Wang & ... See full document
12
The Neuroprotective Effect of Sodium Nitrite on Ischemic Stroke-Induced Mitochondrial Dysfunction via Downregulation of Intrinsic Apoptosis Pathway
... to mitochondrial biogenesis are peroxisome proliferator-activated receptor gamma, coactivator 1-alpha (PGC-1α), nuclear respiratory factors (Nrfs) and mitochondrial transcription factor A ...of ... See full document
7
Differential regulation of doxorubicin-induced mitochondrial dysfunction and apoptosis by Bcl-2 in mammary (MTLn3) cells
... doxorubicin- induced loss of ⌬ was not inhibited at all by caspase inhibi- ...of mitochondrial cytochrome c release (52, ...doxorubicin-induced apoptosis of MTLn3 ...the mitochondrial ... See full document
12
Neuroprotective Potential of Genistein in Mitochondrial Dysfunction Mediated Apoptosis in Diabetic Neuronal Complications
... in mitochondrial bioenergetics, that follows cytochrome c release into cytosol and commences apoptotic cascade and conclude in neuronal damage ...during apoptosis is originated through releasing numerous ... See full document
9
Sirt6 Suppresses High Glucose-Induced Mitochondrial Dysfunction and Apoptosis in Podocytes through AMPK Activation
... [37]. Mitochondrial swelling is a pivotal step for the occurrence of apoptosis as the inner membrane is disrupted and mitochondrial proapoptotic factors are released ...to apoptosis [39]. ... See full document
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