[PDF] Top 20 Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate.
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Molecular characterization of an attenuated human immunodeficiency virus type 2 isolate.
... Nucleotide substitutions are shown with respect to the JSP4-27 sequence, and amino acid sequence changes unique to the cytopathic and fusogenic ST/24 strains are in boldface.. Asterisks [r] ... See full document
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Cytopathic variants of an attenuated isolate of human immunodeficiency virus type 2 exhibit increased affinity for CD4.
... The affinity of F-CD4 for the ST/24.C envelope was also found to be similar to that of the cytopathic HIV-2 isolate HIV-2/ROD 26 ± 2 nM when CD4 binding was evaluated on Sup-Ti cells chr[r] ... See full document
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Molecular Interactions of Human Immunodeficiency Virus Type 1 with Primary Human Oral Keratinocytes
... cell type and the presence of other proapoptotic or antiapop- totic stimuli (21, 30), can either inhibit or promote ...in human or mouse lymphocytes, it has been shown that expression of Ras resulted in ... See full document
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Characterization of human immunodeficiency virus type 1 Vif particle incorporation.
... FIG. 2. Quantitation of Vif in Molt IIIB virions. (A) Top panels: the Vif content of serially diluted virions (lanes 1 to 6, 696 to 2.9 ng of p24) was assessed by immunoblot analysis with an anti-Vif antibody. ... See full document
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Characterization of a live, attenuated human parainfluenza type 3 virus candidate vaccine strain.
... cp45 virus was grown in L-132 cells at 32 or 39.58C, and the virus-infected cell homogenate was analyzed for neuramini- dase ...mg/ml, type IV; Sigma Chemical Com- pany, ...parent virus was ... See full document
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Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual.
... of attenuated HIV strains within ...cultured virus isolate derived from the initial time point stud- ied, as well as two PBMC samples taken 37 and 51 months ... See full document
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Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation.
... in human immunodeficiency virus type 1 reverse transcriptase (RT) develops as a consequence of didanosine (ddI) therapy and is associated with a decreased susceptibility to ...the ... See full document
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Molecular Basis for the Relative Substrate Specificity of Human Immunodeficiency Virus Type 1 and Feline Immunodeficiency Virus Proteases
... In this study we use a combinatorial approach to identify substrates that are efficiently cleaved by HIV-1 PR and FIV PR. A random hexamer peptide library displayed on the phage gene III product was screened with wt ... See full document
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Molecular characterization of biologically diverse envelope variants of human immunodeficiency virus type 1 derived from an individual.
... This leads to a frameshift which results in the JS4 clones encoding 58 amino acids at the carboxy terminus of gp4l compared with 53 in pHXB2gpt, contributed from the gene encoding the ca[r] ... See full document
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Molecular Cloning and Characterization of Viruses Isolated from Chimpanzees with Pathogenic Human Immunodeficiency Virus Type 1 Infections
... Recently, Wei and Fultz (44) described changes in several genomic regions of the virus derived from C499. These data are based on a sampling obtained 22 months before the death of C499 and 17 months prior to our ... See full document
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Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immunodeficiency virus type 1 chimeric virus.
... live, attenuated vaccines have been widely used for prophylaxis against diseases induced by other viral and bacte- rial agents, their potential use for protection of humans against HIV-1 has been controversial ... See full document
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Characterization of Antibody Responses Elicited by Human Immunodeficiency Virus Type 1 Primary Isolate Trimeric and Monomeric Envelope Glycoproteins in Selected Adjuvants
... neutralization also maps to V3 but does not wane; in fact, it increases with repeated inoculations. Taken together, the data suggest that initially the elicited V3 loop antibodies are di- rected against the V3 tip, a ... See full document
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Adaptation of a CCR5-Using, Primary Human Immunodeficiency Virus Type 1 Isolate for CD4-Independent Replication
... primate immunodeficiency viruses into target cells is mediated by the viral envelope glycoproteins, gp120 and gp41, which are organized into trimeric complexes on the virion surface (2, ...the virus ... See full document
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Molecular Characterization of Human Immunodeficiency Virus Type 1 and Hepatitis C Virus in Paid Blood Donors and Injection Drug Users in China
... of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infection due to large numbers of paid blood donors (PBD), injection drug users (IDU), and sexual partners of ... See full document
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Differential Restriction of Human Immunodeficiency Virus Type 2 and Simian Immunodeficiency Virus SIVmac by TRIM5α Alleles
... the human population and the resultant AIDS pandemic underline the threat to human health posed by such retroviral zoonotic ...the molecular mechanisms of the species barriers that protect against ... See full document
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Full-length sequence and mosaic structure of a human immunodeficiency virus type 1 isolate from Thailand.
... simian immunodeficiency virus ...from isolate CM240 and, with repair of the defect in vpu and assembly of the component clones, may provide a full-length, infectious molecular clone for ... See full document
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Determinants of Entry Cofactor Utilization and Tropism in a Dualtropic Human Immunodeficiency Virus Type 1 Primary Isolate
... primary isolate (10), and its Env glycoprotein mediates CD4-dependent fusion and entry with both CCR5 and CXCR-4, as well as CCR3 ...proto- type T-tropic strain HXB, we previously reported that replac- ing ... See full document
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Characterization of human immunodeficiency virus type 2 envelope glycoproteins: dimerization of the glycoprotein precursor during processing.
... Extracts from infected cells panel CELL and from culture medium containing virus particles panel SN were purified on HIV-2 serum-Sepharose to identify the viral glycoproteins gp125, gp14[r] ... See full document
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CXCR4-Dependent Infection of CD8+, but Not CD4+, Lymphocytes by a Primary Human Immunodeficiency Virus Type 1 Isolate
... JR-FL isolate for 2 ...for 2 to 3 days, and the CD4 ⫹ and CD8 ⫹ cells were always analyzed for purity before infection with different viruses ... See full document
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Cyclophilin A-Independent Replication of a Human Immunodeficiency Virus Type 1 Isolate Carrying a Small Portion of the Simian Immunodeficiency Virus SIVMACgag Capsid Region
... The molecular basis for the replication in- competence of various virus clones constructed in this study ...These virus clones generated progeny ...N.Y.), virus amounts were adjusted by RT ... See full document
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