[PDF] Top 20 Molecular and Clinical Diagnosis of Group A Streptococcal Pharyngitis in Children

... (GAS) pharyngitis is a very common condition causing significant morbidity in ...sequelae. Diagnosis of GAS phar- yngitis by a rapid antigen detection test (RADT) or culture in the absence of discriminating ... See full document

... speci fi city, and sample characteristics. Where sensitivity and speci fi city were not presented in the article, we inde- pendently calculated sensitivity and speci fi city from published raw data or from data submitted by ... See full document

... the diagnosis of Group A streptococcal (GAS) pharyngitis in children and to determine differences in diagnostic accuracy in boys versus ...GAS pharyngitis diagnosed with a rapid ... See full document

... Lancefield group A β-hemolytic streptococci) causes 37% of cases of acute pharyngitis in children older than 5 years and is the only agent that requires an etiologic diagnosis and specific ... See full document

... with clinical examination alone and delay in treatment can re- sult in blindness in up to 10% of patients ...in children and can result in significant complications as blindness, cavernous sinus thrombosis, ... See full document

... of all ages with sore throat. The pooled prevalence of GAS from these studies was 37% (95% CI: 32%– 43%). There was substantial heterogeneity among these studies (P ⬍ .001). To explore the reasons for this heterogeneity, ... See full document

... Accurate diagnosis of group A strepto- coccal pharyngitis and appropriate antimicrobial ther- apy are important, particularly to prevent nonsuppu- rative sequelae such as rheumatic ...agents. ... See full document

... 1. A.: The ac- curacy of diagnosis of beta streptococcal infections on clinical grounds. Stillerman, M., and Bernstein, S. H.: Strepto- coccal pharyngitis. G., Mazeika, I., Lee, R., et a[r] ... See full document

... providers, the modified Centor score performance demonstrated moderate agreement. This suggests that patients or parents may be able to accurately identify children at low risk for GAS. Although some GAS-positive ... See full document

... Cost pressures on primary care providers continue to increase as reimbursement decreases and payers in- creasingly value cost-effective considerations when making reimbursement decisions. NAAT and therefore PCR accuracy ... See full document

... for children, parents were encouraged to bring in their chil- dren with a broader set of symptoms, including head- ache, abdominal pain, vomiting, cough, coryza, and ...the clinical details, and treated the ... See full document

... alternate diagnosis (such as herpes gingivostomatitis or hand foot and mouth disease), language barrier or inability to give ...information, clinical data and throat swabs were collected at presentation. ... See full document

... a pharyngitis event between January 1, 2011, and December 31, 2015, were ...identified. Streptococcal pharyngitis was defined by the presence of at least 1 claim during the study period with any ... See full document

... 502933.3 clinical cases of pharyngitis oc- curred in children aged 0–14 years with about ...Although pharyngitis may seem rela- tively benign and unimportant, our study found that it caused as ... See full document

... Knowledge of guidelines is an important factor in ad- herence. Almazrou states: “Knowledge such as lack of fa- miliarity and awareness, volume overload, time needed to stay informed and guideline accessibility are ... See full document

... of pharyngitis is summarized in Table ...that diagnosis of a specific etiological agent based on clinical criteria alone is inadequate for effective ...non- streptococcal etiology, in one ... See full document

... of children diag- nosed as having GAS pharyngitis at 2 pediatric practice sites in the Boston, Massachusetts, metropolitan ...GAS pharyngitis among children who were seen at 1 urban practice ... See full document

... a diagnosis of otitis media, streptococcal pharyngitis, pneumonia, chronic sinusitis, acute sinusitis, urinary tract infection, cellulitis or bacteremia, within seven days before or seven days after ... See full document

... Ensuring that patients see a physician whenever they start having streptococcal pharyngitis like symptoms is important because it allows them to get tested and treated in a timely manner. Although the ... See full document

... Frequency of erythrogenic exotoxin genes in group A streptococcal strains associated clinically with pharyngitis, scarlet fever, and severe invasive disease % of isolates with the Clinic[r] ... See full document