[PDF] Top 20 N (2 Meth­­oxy­benz­yl) 9 (oxolan 2 yl) 9H purin 6 amine

... interacted with 2-methoxybenzylamine and triethylamine (molar ratio of 1: 1.33: 1.67, respectively) in N,N`-dimethyl- formamide (90 °C, 150 min). Again, the solvents were partly evaporated and the ... See full document

... Chloro-9-isopropyl-9H-purine (100 mg, 0.51 mmol) and benzylamine (58 mg, 0.54 mmol) were dissolved in a mixture of DMSO (4 ml) and triethylamine (57 mg, 0.56 mmol). The resulting solution was stirred at 90 ... See full document

... In the title molecule (Fig. 1), the purine unit is essentially planar, with a r.m.s. deviation of 0.0063 (11) Å from the least- squares plane defined by the nine constituent atoms. Although all pyrimidine atoms lie ... See full document

... refluxed at 353 K for 5–10 minutes. The completion of the reaction was monitored by TLC (ethyl acetate and hexane as an eluent 20%). After completion, the reaction mixture was cooled to ambient temperature. Then ... See full document

... O1 0.0319 (5) 0.0260 (5) 0.0370 (5) 0.0089 (4) 0.0218 (4) 0.0074 (4) N1 0.0261 (5) 0.0190 (5) 0.0246 (5) 0.0032 (4) 0.0115 (4) 0.0002 (4) C1 0.0265 (6) 0.0201 (6) 0.0234 (6) 0.0037 (4) 0.0135 (5) ... See full document

... [symmetry code: (i) 1 ÿ x, ÿy, 1 ÿ z] to form centrosymmetric dimers (Fig. 2 and Table 2). The molecular structure of (I) is very similar to those determined for (R)- and (S)-roscovitine (Wang et al., ... See full document

... an N -allylic chain oriented out of the plane described by the bicyclic main ...the N -allylic chain is slightly disordered, with two possible spacial ... See full document

... membered pyrimidine and five-membered imidazole rings merged into the essentially planar purine skeleton (r.m.s. deviation = 0.01 A ˚ ). In the crystal, pairs of N—H N hydrogen bonds link molecules into ... See full document

... benzene ring are almost coplanar [dihedral angles of 6.43 (9) and 0.64 (8) in the two conformers]. The crystal structure is stabilized by intermolecular N—H N interactions that link adjacent ... See full document

... The method to synthesize the title compound was modified from a few papers (Banh et al., 2011; Salvatore et al., 2002; Salvatore et al., 2005). 2-amino-9H-purine-6-thiol (0.598 mmol) was mixed with ... See full document

... rian Gemini 200 MHz FT NMR spectrometer. The chemical shifts are reported in δ ppm relative to TMS. FT-IR spectra were recorded in the solid state as a KBr dispersion using a perkin-Elmer 16428 FT-IR spectro- photometer. ... See full document

... As a continuation of our progress in the development of hybrid drug candidates against tuberculosis, malaria and cancer (Morphy et al., 2004), the title compound was identified as a promising starting material. The ... See full document

... C8 0.0634 (13) 0.0580 (12) 0.0649 (13) −0.0160 (10) 0.0012 (11) 0.0062 (10) C9 0.0518 (11) 0.0591 (12) 0.0503 (11) −0.0089 (9) 0.0128 (9) 0.0067 (9) C10 0.0607 (12) 0.0541 (11) 0.0401 (10) −0.0068 ... See full document

... Fig. 2 shows a part of the herringbone-pattern-like layer parallel to [010] of the title compound. In that figure, the four different hydrogen bonds are shown in different colours. The region with the blue ... See full document

... Experimental electronic absorption spectra of (I) and (II) have been measured and compared to the ground state (HOMO) and excited state (LUMO) molecular orbital ener- gies, calculated using time-dependent DFT ... See full document

... C3 0.0175 (14) 0.0235 (15) 0.0343 (16) 0.0065 (11) −0.0065 (12) −0.0128 (13) C4 0.0239 (15) 0.0207 (15) 0.0415 (18) 0.0052 (12) −0.0044 (13) −0.0145 (14) C5 0.0189 (15) 0.0258 (16) 0.0366 (17) 0.0008 (11) −0.0022 (12) ... See full document

... Department of Chemistry, Tulane University, New Orleans, LA 70118, USA, Department of Physics, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey, cChemistry and Environmenta[r] ... See full document

... phenyl N-tert-Butyl- α -phenylnitrone (PBN), 5,5-dimethyl-pyrroline-N-oxide(DMPPO),4-hydroxy- 2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPOL) and vitamin A, C and E against various NP ... See full document

... In the crystal structure, the molecules are linked to one another through N—H···N hydrogen bonds generating R228 ring patterns Bernstein et al., 1995 forming inversion related dimers.. T[r] ... See full document

... C24 0.106 (3) 0.107 (3) 0.118 (3) −0.028 (2) 0.015 (2) 0.000 (2) N2 0.0712 (13) 0.0541 (11) 0.0558 (11) 0.0035 (10) 0.0176 (10) 0.0101 (9) N1 0.0462 (10) 0.0529 (11) 0.0588 (11) 0.0045 ... See full document