[PDF] Top 20 Negative modulation of Epstein-Barr virus episomes by a human B-cell growth factor.

... As demonstrated by the slot blot technique, DNA derived from Raji cells as well as from the lymphoblastoid cell line maintained in the presence of BCGF-12kD exhibited a significant reduc[r] ... See full document

... mutant virus, in which all three AP-2-binding sites were mutated (⫺75, ⫺100, and ⫺205), and another virus, in which two sites ( ⫺ 100 and ⫺ 205) were modified ...to human primary B cells for ... See full document

... Epstein-Barr virus (EBV) infection is associated with many human ...primary B lymphocytes into continuously growing lymphoblastoid cell ...regulatory factor 4 (IRF-4) is a ... See full document

... GC cell survival. Elsewhere, gene expression profiling of B cells during stages of GC transit (naive to centroblast [CB] to memory cells) showed that genes known to exert proapo- ptotic functions, including ... See full document

... of cell number and proliferation ...of cell proliferation, ...vergent growth profiles manifest by the three infected clones, growth properties of randomly chosen EBV-negative ... See full document

... the human B-cell line Louckes (15, 19, ...Louckes human EBV- negative B cells into the same mouse induced the formation of a small tumor that regressed after 3 ...Louckes ... See full document

... LCV-induced B-cell immortalization beyond virus binding and ...infect human B cells, EBNA-2 and CD23 are ex- pressed in human B cells after acute simian LCV infection, and ... See full document

... As growth of LCL tumors in SCID mice is characterized by abundant angiogenesis (69) and angiogen- esis inhibitors prevent growth of lymphoma cells in mice (48), the impaired capacity of Z-KO LCLs to secrete ... See full document

... epithelial cell clones contain- ing EBV episomes with minimal terminal repeats became pre- dominant in culture, with LMP2A levels varying inversely with terminal repeat units ...transformed cell ... See full document

... Epstein-Barr virus (EBV) is an oncogenic herpesvirus capa- ble of transforming primary B lymphocytes into indefinitely proliferating lymphoblastoid cell lines ...and human ... See full document

... Activation of transcription of heterologous and native EBV promoters by derivatives of EBNA-1. Derivatives of EBNA-1 (Fig. 1A) were tested for the ability to activate transcription from either a heterologous promoter, ... See full document

... EBV infection, may not measure the same events as the clas- sical regression assay. Nonetheless, our quantitative assay sys- tem reproduces many of the findings of the classical regression assay, in which foci of ... See full document

... These results and those of previous studies of Epstein-Barr virus promoters regulated by BZLF1 indicate that BZLF1 requires adjacent multiple DNA-binding sites for cooperative interactio[r] ... See full document

... other cell types in vivo, it is clearly important to prevent the activation of the transforming program in an inappropriate ...the B-cell-specific protein BSAP as a key regulator of the promoter that ... See full document

... patterns, cell-type signatures, BCR diversity, and histopathology, such as inflammation and cancer ...inflammatory cell (B, T, and NK) influx were second, or whether EBV-infected B cells were the ... See full document

... 703-708 0022-538X/82/020703-06$02.00/0 NOTES Induction of Epstein-Barr Virus Nuclear Antigen and DNA Synthesis in a Human Epithelial Cell Line After Epstein-Barr Virus Infection Received[r] ... See full document

... 4079-4084 0022-538X/89/094079-06$02.00/0 Copyright © 1989, American Society for Microbiology Epstein-Barr Virus Latent Infection Membrane Protein Increases Vimentin Expression in Human B[r] ... See full document

... pstein-Barr virus (EBV) is a member of the Gammaherpesviri- dae subfamily of herpesviruses, which has a pronounced prev- alence in humans, as up to more than 90% of the world’s popula- tion is estimated to ... See full document

... Characteristics of sfBIT and sfBT cell linesa Cell line Origin cell line Plasticware adherence General cell morphology Mean doubling time days Maximum density cells/ml sfBIT sfBT B95-8 s[r] ... See full document

... 1245 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest In this study we used Gardella gel analysis of intact DNA, Southern blotting of digested DNA, and fluorescence in s[r] ... See full document