[PDF] Top 20 On New Host Cell Proteins Involved in Alphavirus Replication.
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On New Host Cell Proteins Involved in Alphavirus Replication.
... of proteins or other potential virus receptors in the liposomes ...although alphavirus and influenza encode different classes of fusion proteins, one mechanistic quandary ...fusion proteins of ... See full document
140
Role for nsP2 Proteins in the Cessation of Alphavirus Minus-Strand Synthesis by Host Cells
... antiviral host response and shutting off minus-strand synthesis? If the failure to cease PI replicon minus-strand synthesis was due to a change in the host response by cells that had been selected during ... See full document
12
Comparative Characterization of the Sindbis Virus Proteome from Mammalian and Invertebrate Hosts Identifies nsP2 as a Component of the Virion and Sorting Nexin 5 as a Significant Host Factor for Alphavirus Replication
... virus-associated host protein content, ultrapure preparations of virions were ...prepared. Host background contamination from cellular vesicles or debris not specifically incorporated needs to be eliminated ... See full document
17
Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection
... unfolded proteins, depletion of ER membranes for virus assembly and release, competition with host proteins for modifications by viral glyco- proteins, ...unfolded proteins from the ER ... See full document
17
The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates
... of proteins that interact with the immune system of the host, as formerly reported for other apicomplexan species (Templeton et ...candidate proteins involved in host interaction and ... See full document
14
Purification of Host Cell Enzymes Involved in Adeno-Associated Virus DNA Replication
... uninfected-293 cell extracts. A DEAE-Sepharose frac- tionation of uninfected-cell IIA proteins yielded two peaks of polymerase activity ...DNA replication showed that the Pol ␦ peak fractions ... See full document
11
Patterns of evolution of host proteins involved in retroviral pathogenesis
... Second, the failure to identify signatures of positive selec- tion in the TRIM19 (PML) gene suggests that its encoded protein does not have antiviral activity, or that the protein acts as an intermediary, lacking a ... See full document
7
Viral and host proteins involved in picornavirus life cycle
... the cell lines and the virus isolates ...the cell and host range. However, the interaction of capsid proteins with intracellular host factors is also ... See full document
14
Probing the Sites of Interactions of Rotaviral Proteins Involved in Replication
... a new cytoplasmic form of NSP2 has been characterized that interacts with cellular and viral proteins, including VP2 ...RNA replication and core assembly (36, ... See full document
16
Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication
... the host factors identified, YBX1, NCL, and HNRNPC have been reported to be involved in DENV replication in the context of infection (10, 33, ...observe cell type-specific differences in the ... See full document
10
Functional Consequences of RNA 5′-Terminal Deletions on Coxsackievirus B3 RNA Replication and Ribonucleoprotein Complex Formation
... infections involved group B ...length, involved a 5= RNA secondary structure (S-L I) that is the binding site for both viral and host cell proteins forming RNA replication ... See full document
17
Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells
... unknown host transport ...of alphavirus infection in mosquito cells, where virus budding occurs initially at the PM, but at ~9 h ...and replication proteins and dsRNA outside the limiting ... See full document
16
Host Cell S Phase Restricts Legionella pneumophila Intracellular Replication by Destabilizing the Membrane Bound Replication Compartment
... eukaryotic cell cycle is a known target of viral and bacterial pathogens, which either stimulate cell division or prevent it (55, ...the host cell cycle is ...a cell cycle arrest ...the ... See full document
18
Identification of Genes Involved in the Host Response to Neurovirulent Alphavirus Infection
... A subset of genes that are involved in IFN signaling or regulated by IFNs have increased expression in dsTE12H- and dsTE12Q-infected brains. IFN-␣/ are known to play a critical role in defense against Sindbis ... See full document
15
Murine Cytomegalovirus (CMV) M33 and Human CMV US28 Receptors Exhibit Similar Constitutive Signaling Activities
... in host cell signaling ...is involved in M33- and US28-mediated CREB activation but not NF- B ...regulating host gene transcription, ...such proteins in the viral envelope, suggest ... See full document
8
Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179.
... poliovirus proteins 2B and 3A in COS-7 cells blocks protein secretion ...ral proteins 2BC, 2B, 2C, and 3A affected the integrity of the Golgi ...viral proteins for peri- ods of 16 to 48 h and by ... See full document
15
Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in Streptococcus pneumoniae D39
... These findings suggest that spd1025 to spd1028 may well encode a bona fide pyruvate dehydrogenase complex. In strong support of this assignment, deletion of S. pneumoniae TIGR4 genes sp1163 and sp1164 (corresponding to ... See full document
25
Identification of BV/ODV-C42, an Autographa californica Nucleopolyhedrovirus orf101-Encoded Structural Protein Detected in Infected-Cell Complexes with ODV-EC27 and p78/83
... acrylamide gels and purified in a nondenatured state using glutathione-agarose) were produced. Antibodies reacted with whole-cell lysates that were collected throughout the time course of infection detected a ... See full document
8
RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins
... the alphavirus-like capping enzymes (31, 32), crucially contributes to the enzymatic activity of nsP1, since the mutant phenotype is similar to those of the other active site mutants and not to those of the ... See full document
6
Rosenberg, Eva (2010): Aggregation of therapeutic antibodies in the course of downstream processing. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... In the presence of the nano- and micro-sized solid particles, as reported above, partial unfolding of the protein molecules was hardly recognized, although the formation of ag- gregates was clearly enhanced and the ... See full document
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