[PDF] Top 20 Nuclear Import of the Preintegration Complex Is Blocked upon Infection by Human Immunodeficiency Virus Type 1 in Mouse Cells
Has 10000 "Nuclear Import of the Preintegration Complex Is Blocked upon Infection by Human Immunodeficiency Virus Type 1 in Mouse Cells" found on our website. Below are the top 20 most common "Nuclear Import of the Preintegration Complex Is Blocked upon Infection by Human Immunodeficiency Virus Type 1 in Mouse Cells".
Nuclear Import of the Preintegration Complex Is Blocked upon Infection by Human Immunodeficiency Virus Type 1 in Mouse Cells
... the nuclear localization of a GFP-IN fusion protein ...vitro nuclear import of IN does not require known cytosolic transport factors, including karyopherin  family pro- teins ...living cells ... See full document
12
Evidence for a Functional Link between Uncoating of the Human Immunodeficiency Virus Type 1 Core and Nuclear Import of the Viral Preintegration Complex
... target cells, the capsid of HIV-1 disassociates from the viral RNP in a process of un- ...infected cells (27) and the paucity of CA present in purified HIV-1 PICs (19, ...from cells ... See full document
9
Novel Nuclear Import of Vpr Promoted by Importin α Is Crucial for Human Immunodeficiency Virus Type 1 Replication in Macrophages
... the nuclear import of Vpr but also for viral replication in ...after infection with the HIV-based vector, whereas there are no detectable two-long-terminal-repeat vector circles in mono- cytes, ... See full document
10
Evaluation of the Functional Involvement of Human Immunodeficiency Virus Type 1 Integrase in Nuclear Import of Viral cDNA during Acute Infection
... acute infection of hu- man primary cells ...nondividing cells such as monocyte-derived macrophages ...the nuclear import of viral ...the nuclear import of viral cDNA, the ... See full document
11
Importin-α Promotes Passage through the Nuclear Pore Complex of Human Immunodeficiency Virus Type 1 Vpr
... This import was totally energy independent and observed in the presence of ...this import. These profiles ob- served on the nuclear import of importin-a by itself are con- sistent with that of ... See full document
8
Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1
... positive cells, was significantly reduced to ...the cells were transfected with the NUP153C expression construct, as demonstrated by a cotransfection control (data not ...the nuclear import of ... See full document
12
The C-Terminal Proline-Rich Tail of Human Immunodeficiency Virus Type 2 Vpx Is Necessary for Nuclear Localization of the Viral Preintegration Complex in Nondividing Cells
... In addition to Vpr, HIV-2 and members of the simian im- munodeficiency virus SIVsm/SIVmac lineage encode Vpx. Vpx and Vpr share considerable homology (42, 44). Like Vpr, Vpx is virion associated and recruited into ... See full document
6
Reassessment of the Roles of Integrase and the Central DNA Flap in Human Immunodeficiency Virus Type 1 Nuclear Import
... When cells were mock infected ...wild-type infection (Fig. 5C and C⬘) were almost entirely nuclear and, presumably, represented both unintegrated and integrated ...mainly nuclear and ... See full document
10
Nuclear Import Defect of Human Immunodeficiency Virus Type 1 DNA Flap Mutants Is Not Dependent on the Viral Strain or Target Cell Type
... indicator cells. Viruses were produced by transient transfection of HeLa cells using calcium phosphate coprecipitation with the proviral ...FIG. 1. One-round titration assay of wild-type ... See full document
8
Lys-34, Dispensable for Integrase Catalysis, Is Required for Preintegration Complex Function and Human Immunodeficiency Virus Type 1 Replication
... acting upon the viral attachment (att) sites at the ends of linear viral cDNA within the context of a large nucleoprotein complex referred to as the preintegration complex ...For human ... See full document
8
The Karyophilic Properties of Human Immunodeficiency Virus Type 1 Integrase Are Not Required for Nuclear Import of Proviral DNA
... of virus replication for HIV-1 mutants carrying karyophilic IN proteins (viruses WT and N) and nonkaryophilic ones (L, Q, and LQ), with partic- ular interest in the nuclear import of ...impair ... See full document
8
Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import.
... the human immunodeficiency virus type 1 (HIV-1) nucleoprotein complex with the cell nuclear import machinery is necessary for viral replication in ... See full document
6
Hsp40 Facilitates Nuclear Import of the Human Immunodeficiency Virus Type 2 Vpx-Mediated Preintegration Complex
... U937 cells stably expressing either Hsp40/DnaJB6 or GFP siRNA or JC53BL cells containing pCNF-B6 (Hsp40/DnaJB6) or pCNF were infected with HIV-2rod10 for the indicated times and then washed with ...U937 ... See full document
9
Nuclear Localization of Human Immunodeficiency Virus Type 1 Preintegration Complexes (PICs): V165A and R166A Are Pleiotropic Integrase Mutants Primarily Defective for Integration, Not PIC Nuclear Import
... immunofluorescence, cells washed with phos- phate-buffered saline (PBS) (pH ...and blocked for 30 min in 5% bovine serum albumin (BSA) in PBS. Fixed cells were incubated for 1 h at ambient ... See full document
10
Molecular Characterization of Preintegration Latency in Human Immunodeficiency Virus Type 1 Infection
... and virus gene expression, events that are not generally observed in resting T cells in the absence of an activating stimulus ...T cells traffick- ing through peripheral tissues in vivo may be ... See full document
14
LFA-1 Expression on Target Cells Promotes Human Immunodeficiency Virus Type 1 Infection and Transmission
... for virus-cell attachment, we demonstrated here for the first time that to promote efficient cell-to-cell spread of HIV, the presence of activated and highly avid LFA-1 on the cell surface is not ... See full document
6
Cellular Gene Expression upon Human Immunodeficiency Virus Type 1 Infection of CD4+-T-Cell Lines
... the virus life ...heterogeneous nuclear ribonucleoproteins was ...HIV-1 infection, implicating these factors in facilitating HIV-1 ...BRU infection (van ’t ... See full document
11
Differential Susceptibility to Human Immunodeficiency Virus Type 1 Infection of Myeloid and Plasmacytoid Dendritic Cells
... of infection and depletion of ...of virus exposure. We exposed MDCs and PDCs to 1 g p24/ml of HIV-1 for 72 h, which resulted in a p24 ⫹ population of DCs, without induction of cell death ... See full document
9
Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection.
... 3345 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest Viral RNA was extracted from plasma samples collected from five individuals during the period of viremia before sero[r] ... See full document
12
Phagocytic Activity in Human Immunodeficiency Virus Type 1 Infection
... from 1 to 1,000 ng/ml of viral protein ...these cells’ ability to stimulate autologous lymphocytes in response to anti-CD3, accompanied by a significant decrease in CD4 and Fc receptor ... See full document
7
Related subjects