[PDF] Top 20 Ocular surface epithelial and stem cell development
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Ocular surface epithelial and stem cell development
... this stem cell and the overall homeostatic mechanisms that foster its survival within the limbal ...viable stem cells. Stem cells are identified by their unique slow cycling ...from ... See full document
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Optimised laser microdissection of the human ocular surface epithelial regions for microarray studies
... OS epithelial regions were as follows: UV energy 58-70 μJ, UV focus 75-80 μm, and UV speed 60-70 μm 2 ...adjacent epithelial cell layer during LMD, hence adversely influencing the molecular ... See full document
13
Treating ocular surface disease: new agents in development
... combating ocular surface disease and dysfunctional tear syndrome has been the application of autologous ...the ocular sur- ...persistent epithelial defects, superior limbic kera- ... See full document
8
<p>Keratograph 5M As A Useful And Objective Tool For Evaluating The Ocular Surface In Limbal Stem Cell Deficiency</p>
... In the initial visit, we recorded age, sex, and etiology of the limbal stem cell de fi ciency and performed the tradi- tional OSDI questionnaire and a slit-lamp examination of the BUT. The OSDI employed was ... See full document
9
Mesenchymal stem cells for treating ocular surface diseases
... the ocular surface causing epithelium wounds, corneal stroma opa- city and/or neovascularization, to much more severe which penetrates into the eye leading to persistent intra- ocular inflammation ... See full document
11
Clinical Applications of Stem Cells in Ocular Surface Reconstruction
... f stem cells for autologous corneal ...differentiated cell sheets which closely resembled in vivo corneal epithelium and were found to be useful in the treatment of bilateral limbal stem cell ... See full document
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Limbal stem cell transplantation: current perspectives
... corneal surface after an epithelial insult involves division, migration, and maturation of a specialized group of stem cells located in the ...limbal stem cell deficiency ...persistent ... See full document
10
Lgr proteins in epithelial stem cell biology
... the cell surface (Carmon et ...intestinal stem cells may therefore have evolved as a means of selectively amplifying canonical Wnt signals above a threshold compatible with ensuring stem ... See full document
11
Stem Cell Research: A Novel Boulevard towards Improved Bovine Mastitis Management
... like epithelial, myoepithelial and or cuboidal/columnar cells in the ...major cell types, epithelial and myoepithelial stem/progenitor cells are of considerable therapeutic interest in mammary ... See full document
12
Downregulation of miR122 by grainyhead like 2 restricts the hepatocytic differentiation potential of adult liver progenitor cells
... liver stem/ progenitor cells (LPCs), which share surface markers, including epithelial cell adhesion molecule (EpCAM), with cholangiocytes and differentiate into both hepatocytes and ... See full document
9
Update on pharmacotherapy for ocular surface squamous neoplasia
... an epithelial thickness cut off of approximately 140 μm on OCT images ...an epithelial thickness cut off of 120 μm on OCT images ...co-existing ocular surface dis- eases (such as rosacea, ... See full document
12
Ocular stem cells: a status update!
... from stem cells for regenerative ...organ. Cell-based therapies using stem cells from the ciliary body, iris and sclera are still in animal experimental stages but show potential for replacing ... See full document
12
Therapeutic uses of scleral contact lenses for ocular surface disease: patient selection and special considerations
... limbal stem cell deficiency, neurotrophic keratitis, exposure keratitis, PEDs, and cicatrizing conjunctivitis can all benefit from therapeutic scleral ...severe ocular surface disease recal- ... See full document
10
MicroRNA 205 signaling regulates mammary stem cell fate and tumorigenesis
... the stem/progenitor cell niche are critical for governing the cell fate decision (5, ...cancer stem cell phenotype ...mammary epithelial cells (HMEC) under jagged1 treatment ... See full document
15
Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis
... However, epithelial-like cells may be tumorigenic with cancer stem-like characteristics which may enhance SKOV3-Luc tumor growth and recapitulate in the original ...Both cell populations in this ... See full document
14
Goblet cell loss abrogates ocular surface immune tolerance
... antagonist. Epithelial cells in the intestine and stomach have also been noted to produce RA that functions to maintain immune tolerance in these tissues (21, ... See full document
12
Xenofree generation of limbal stem cells for ocular surface advanced cell therapy
... for cell detachment was not completely inhibited by defined media, which usually contain low concentration of pro- teins and other elements such as ...the cell viability loss in CLET could impair the ... See full document
12
Twenty years of limbal epithelial therapy: an update on managing limbal stem cell deficiency
... persistent epithelial defects (PEDs) have been considered as criteria for clin- ical success in ...several ocular surface chronic conditions were transplanted with ... See full document
7
TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium
... severe ocular surface diseases (Li et ...a stem cell niche containing limbal stem cells that migrate centripetally to maintain the cornea (Pellegrini et ...inner surface of the ... See full document
12
Comparison of cytotoxicities and anti-allergic effects of topical ocular dual-action anti-allergic agents
... mast cell surface ...damage ocular surface cells [7–9]. An impaired epithelial barrier may allow allergens to infil- trate easily and exacerbate the ... See full document
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