[PDF] Top 20 Optimization of Human Immunodeficiency Virus Gag Expression by Newcastle Disease Virus Vectors for the Induction of Potent Immune Responses
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Optimization of Human Immunodeficiency Virus Gag Expression by Newcastle Disease Virus Vectors for the Induction of Potent Immune Responses
... HIV Gag from every position except in front of ...on virus growth (35, 36). In our case, the inability to rescue a virus with HIV gag in this position might be related to the insert size ... See full document
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Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Specific Immune Response in Mice
... HIV-1 Gag protein and demonstrated its ability to induce a potent Gag-specific CD8 ⫹ T cell response in mice ...cell induction (5, ...many human HLA haplotypes (3). A DNA vaccine ... See full document
12
Mucosal Immunization with Newcastle Disease Virus Vector Coexpressing HIV 1 Env and Gag Proteins Elicits Potent Serum, Mucosal, and Cellular Immune Responses That Protect against Vaccinia Virus Env and Gag Challenges
... p55 Gag and its cleavage products were de- tected in fractions 4 to 9, indicating the presence of HIV VLPs ...9. Expression of the NDV HN protein and HIV-1 Gag and Env proteins peaked in the same ... See full document
10
Mycobacterial Codon Optimization Enhances Antigen Expression and Virus-Specific Immune Responses in Recombinant Mycobacterium bovis Bacille Calmette-Guérin Expressing Human Immunodeficiency Virus Type 1 Gag
... vaccinia virus Ankara (4, 21), adenovirus type 5 (29), fowlpox virus (16), canarypox virus (8), and NYVAC ...ated immune responses without triggering humoral ...induce disease ... See full document
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Enhancement of Primary and Secondary Cellular Immune Responses against Human Immunodeficiency Virus Type 1 Gag by Using DNA Expression Vectors That Target Gag Antigen to the Secretory Pathway
... the induction of immune re- sponses after ...the induction of immune responses after ...of immune responses ...CTL responses than did the Cy-Gag molecules in ... See full document
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Newcastle Disease Virus Expressing Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Induces Strong Mucosal and Serum Antibody Responses in Guinea Pigs
... Human immunodeficiency virus type 1 (HIV-1) is transmitted mainly through mucosal ...the induction of systemic and mucosal immune responses by the use of Newcastle ... See full document
13
Expression of Human Immunodeficiency Virus Type 1 gp120 from Herpes Simplex Virus Type 1-Derived Amplicons Results in Potent, Specific, and Durable Cellular and Humoral Immune Responses
... Aujesky’s disease (pseudorabies virus), in- fectious bovine rhinotracheitis, and swine fever (hog cholera virus) (21, 56, ...for human vaccination (including the Towne strain of human ... See full document
16
Newcastle Disease Virus Vector Producing Human Norovirus-Like Particles Induces Serum, Cellular, and Mucosal Immune Responses in Mice
... in human and mouse immune systems are known, but mice are frequently used for evaluating vaccine candidates before vac- cines move to human trials ...rNDV vectors were all healthy and did not ... See full document
10
Evaluation of Novel Human Immunodeficiency Virus Type 1 Gag DNA Vaccines for Protein Expression in Mammalian Cells and Induction of Immune Responses
... HIV-1 gag, mostly in third-site positions, without changing the amino acid sequence of the produced Gag protein can result in efficient expression of Gag in a Rev- and RRE-independent fashion ... See full document
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Induction of Potent Immune Responses by Cationic Microparticles with Adsorbed Human Immunodeficiency Virus DNA Vaccines
... induce immune re- sponses and protective immunity in many animal models of infectious disease (for a review, see reference ...such responses can often be achieved with low doses (⬍1 g) of naked ... See full document
7
Direct Comparison of Antigen Production and Induction of Apoptosis by Canarypox Virus- and Modified Vaccinia Virus Ankara-Human Immunodeficiency Virus Vaccine Vectors
... molecules, expression of viral proteins that interfere with IFN and tumor necrosis factor signaling pathways, and expression of molecules that directly interfere with caspase ...in human cells and ... See full document
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Hyperattenuated Recombinant Influenza A Virus Nonstructural-Protein-Encoding Vectors Induce Human Immunodeficiency Virus Type 1 Nef-Specific Systemic and Mucosal Immune Responses in Mice
... influenza virus vec- tors were ...NS-Nef virus vectors might be ex- plained by the fact that viruses containing truncated forms of the NS1 protein induce high levels of type I IFNs in vivo (18, ... See full document
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Analysis of Human Immunodeficiency Virus Type 1 Gag Ubiquitination
... the virus pellets were resuspended in a buffer containing 1% SDS and boiled for 10 ...24). Gag samples were adjusted to equal amounts of Gag (as quantified by p24 ELISA), and the whole precipitates ... See full document
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Chimeric Plant Virus Particles as Immunogens for Inducing Murine and Human Immune Responses against Human Immunodeficiency Virus Type 1
... using human MAb 2F5 ...The immune response of mice intranasally or intraperitoneally immunized with purified CVPs (PVX-2F5E) or with WT PVX or PBS as controls was studied according to the schedule reported ... See full document
6
JC Virus-Specific Immune Responses in Human Immunodeficiency Virus Type 1 Patients with Progressive Multifocal Leukoencephalopathy
... fatal disease caused by uncontrolled polyomavirus JC (JCV) in severely immunodeficient ...T-cell responses were lower in nonsurvivors than in their matched controls (P ⴝ ...(IgG) responses (P ⴝ ... See full document
8
Prime-Boost Vaccination with Recombinant Mumps Virus and Recombinant Vesicular Stomatitis Virus Vectors Elicits an Enhanced Human Immunodeficiency Virus Type 1 Gag-Specific Cellular Immune Response in Rhesus Macaques
... cellular immune responses directed against one or more HIV-1 pro- teins may be sufficient to prevent HIV-1-infected humans from developing AIDS in the absence of broadly neutralizing anti- bodies ... See full document
11
Acute Effects of Pathogenic Simian-Human Immunodeficiency Virus Challenge on Vaccine-Induced Cellular and Humoral Immune Responses to Gag in Rhesus Macaques
... Simian-human immunodeficiency virus (SHIV) infection in macaques provides a convenient model for testing vaccine efficacy and for understanding viral pathogenesis in ...(expressing Gag) or ... See full document
7
Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1.
... of immunodeficiency, and he was reclassified as a ...four Gag and Env antigens were extremely high (especially the anti-p24 titer [see above]), but his anti-Gag titers had started to decline in the ... See full document
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Hybrid human immunodeficiency virus Gag particles as an antigen carrier system: induction of cytotoxic T-cell and humoral responses by a Gag:V3 fusion.
... 6 0022-538X/93/063191-08$02.00/0 Copyright C 1993, American Society for Microbiology Hybrid Human Immunodeficiency Virus Gag Particles as an Antigen Carrier System: Induction of Cytotoxi[r] ... See full document
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Functional chimeras of the Rous sarcoma virus and human immunodeficiency virus gag proteins.
... The results indicate that the first 10 amino acids of the human immunodeficiency virus HIV Gag protein can suppress the block to budding caused by deletions in the RSV MA sequence, much [r] ... See full document
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