[PDF] Top 20 Organ dysfunction as a new standard for defining sepsis
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Organ dysfunction as a new standard for defining sepsis
... of sepsis was made with re- spect to the former definition, which often predis- posed the failure of vital organs, currently referred to as multiple organ dysfunction syndrome ...Thus, sepsis ... See full document
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Levosimendan for the prevention of acute organ dysfunction in sepsis
... of organ dysfunction in adults with ...to standard care. The primary outcome was the mean daily Sequential Organ Failure Assessment (SOFA) score in the intensive care unit up to day 28 (scores ... See full document
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A multiplex analysis of sepsis mediators during human septic shock: a preliminary study on myocardial depression and organ failures
... various sepsis media- tors using hierarchical clustering; this method builds homogeneous clusters based on dissimilarities or dis- tances between cases and proceeds iteratively to join the most similar ...of ... See full document
9
Rs1800625 in the receptor for advanced glycation end products gene predisposes to sepsis and multiple organ dysfunction syndrome in patients with major trauma
... of sepsis met the criteria recommended by the American College of Chest Physicians and Society of Critical Care Medicine Consensus Conference ...a new or changing pulmonary infiltrate on patients’ chest ... See full document
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Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort
... This retrospective subset analysis of the open-label ENHANCE trial has a number of other limitations because of the post hoc and subgroup analyses. A sample size of 305 homogeneous patients may have biased the results ... See full document
10
Clinical utility of biomarkers of endothelial activation in sepsis a systematic review
... and sepsis in varied samples of critically ill ...used standard sepsis definitions, with consistent association between Ang-2 levels and sepsis, as well as relatively con- sistent associations ... See full document
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Multiple Organ Dysfunction Syndrome (MODS): Is It Preventable or Inevitable?
... Multiple organ dysfunction syndrome (MODS) is a systemic, dysfunctional inflammatory response that requires long intensive care unit (ICU) ...that organ failure does not occur as an all-or-none rule, ... See full document
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An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan dysfunction in Sepsis (LeoPARDS ) : protocol for a randomized controlled trial
... normal standard care and be managed in accordance with current accepted best prac- tice as recommended by the Surviving Sepsis Campaign (SSC) guidelines ... See full document
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Predicting the clinical trajectory in critically ill patients with sepsis: a cohort study
... of sepsis oc- curring at admission; in addition, most discharges and deaths occurred before day 14 ...a new conceptual framework for mod- eling of clinical sepsis responses rather than a directly ... See full document
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The effect of diabetes mellitus on organ dysfunction with sepsis: an epidemiological study
... for organ dysfunction as a ...in organ dysfunction between patients with and without DM and ...acute organ dysfunction is crucial to improve our understanding of the mechanisms ... See full document
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The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis
... tion. Sepsis was comprised ED patients with suspected infection with or without systemic inflammatory response syndrome ...Severe Sepsis was defined as sepsis with concomitant organ ... See full document
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Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study
... severe sepsis attended in the ICU of ...more organ failures were present at diagnosis in ...severe sepsis in our ...of organ failure assessed by the SOFA score was significantly different in ... See full document
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Year in review 2010: Critical Care multiple organ dysfunction and sepsis
... on organ failure ...total organ failures and increased organ failure-free days, which is the presumed causative factor for reduced mortality in SPRINT ...a new and interesting approach to ... See full document
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Inflammatory cytokines and organ dysfunction associate with the aberrant DNA methylome of monocytes in sepsis
... with sepsis rapidly display signs of profound immuno- suppression, associated with an increase in hypoxia in- ducible factor-1α expression that drives functional reprogramming ... See full document
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The impact of atrial fibrillation in patients with COPD during hospitalization
... acute organ dysfunction, severe sepsis, respiratory failure, and death during the hospitalization ...acute organ dysfunction, severe sepsis, respiratory failure, and death, were ... See full document
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Correlation of procalcitonin and C reactive protein to inflammation, complications, and outcome during the intensive care unit course of multiple trauma patients
... of sepsis or the respective complications at this specific time ...of sepsis in this ...of sepsis as compared with the noninfection-related severe SIRS ... See full document
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Prevalence of systemic inflammatory response syndrome (SIRS) in hospitalized children: a point prevalence study
... developed sepsis, 5% (n = 3) severe sepsis and 2% (n = 1) septic ...severe sepsis and septic shock had an underlying ...and sepsis recognized by doctors and the diagnoses were not recorded on ... See full document
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Circulating cell death biomarker TRAIL is associated with increased organ dysfunction in sepsis
... A strength of our study comes from the evaluation of TRAIL in patients from 3 independent ICUs with differing practice patterns and baseline characteristics. Using the WC-BOCI cohort as the derivation cohort to establish ... See full document
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Procalcitonin and C reactive protein during systemic inflammatory response syndrome, sepsis and organ dysfunction
... severe sepsis or septic shock with documented infections ...of organ dysfunction has not been conducted in these ...of organ dysfunction has been published previously, supporting the ... See full document
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Mortality in sepsis versus non sepsis induced acute lung injury
... Patient demographic and severity of illness variables Patient-related exposures of interest (independent variables) included patient demographics and several measures of severity of illness. These included: Acute ... See full document
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