[PDF] Top 20 Original Article An associated classification of triple negative breast cancer: the risk of relapse and the response to chemotherapy
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Original Article An associated classification of triple negative breast cancer: the risk of relapse and the response to chemotherapy
... was associated with small tumor size, lower percentage of node positivity, but higher tumor grade, mostly expres- sion of EGFR/CK5/6, p53 labeling index and higher family history of BC ... See full document
12
Original Article Topoisomerase IIα and BRCA1 expression as predictive factors for anthracycline-based adjuvant chemotherapy response and prognosis in triple-negative breast cancers
... better relapse-free survival for patients with TOP2A gene amplification who were treated with a tailored and dose-escalat- ed CEF regimen compared with those treated with low-dose CEF followed by CTCb (cyclop- ... See full document
10
Original Article Expression of cleaved caspase-3 predicts good chemotherapy response but poor survival for patients with advanced primary triple-negative breast cancer
... motherapy response and prognosis of patients with advanced primary triple-negative breast cancer ...was associated with a higher first-line chemotherapy overall ... See full document
11
THE ROLE OF CHEMOTHERAPY IN TRIPLE NEGATIVE BREAST CANCER
... Triple-negative breast cancers have a relapse pattern that is very different from hormone-positive breast cancers: the risk of relapse is much higher for the first 3–5 ... See full document
5
Original Article Let-7f and miRNA-126 correlate with reduced cardiotoxicity risk in triple-negative breast cancer patients who underwent neoadjuvant chemotherapy
... negatively associated with LVEF in dilated cardiomyopathy ...the risk of car- diac dysfunction caused by ischemia and might protect TNBC patients from drug-induced car- ...the risk of myocardial ... See full document
9
Ki 67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis
... The significance of the difference in the variables among two Ki-67 groups was calculated using Chi-square test or Fisher ’ s exact test, where appropriate. The Kaplan- Meier product limit method and the Cox proportional ... See full document
7
<p>A Six-Epithelial–Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer</p>
... of breast cancers using endocrine therapy and targeted therapy, 6,7 non-surgical management of TNBC remains largely limited to chemotherapy, alone or in combination with poly (ADP-ribose) polymerase (PARP) ... See full document
13
The clinical promise of immunotherapy in triple-negative breast cancer
... Abstract: Triple-negative breast cancer (TNBC) is a heterogeneous disease with poorer outcomes compared to other breast cancer ...of relapse and rapid progression after ... See full document
11
Original Article Identification of lncRNAs via microarray analysis for predicting HER2-negative breast cancer response to neoadjuvant chemotherapy
... diagnosed cancer in females, and a large number of patients, espe- cially those with HER2-negative BC, experience treatment failure due to recurrence and metas- ...After chemotherapy, the morphol- ... See full document
8
Original Article Prognostic value of ultrasound BI-RADS classification in triple-negative breast cancer patients received neoadjuvant chemotherapy
... 114 triple-negative breast cancer patients who received neoadjuvant chemother- apy at The Third Affiliated Hospital of Soochow University from October 2006 to December 2015 were ...(Her-2) ... See full document
6
Original Article Plasma CAMK2A predicts chemotherapy resistance in metastatic triple negative breast cancer
... based chemotherapy. Treatment response was assessed after two cycles of che- motherapy by the RECIST criteria ...partial response (PR) were consid- ered aschemotherapy-sensitive (S) ...of ... See full document
14
Original Article Morphological and gene-expression characterization of viable heterogeneous circulating tumor cells size-captured and cultured from triple-negative breast cancer mouse models
... We previously reported that hormone-refracto- ry PC-3 human prostate cancer cells growing orthotopically efficiently produce CTC. This is in contrast to the ectopic tumors of the same cell line, which do not ... See full document
8
Reproductive factors and hormone receptor status among very young (<35 years) breast cancer patients
... classify breast cancer subtypes into more detailed molecular sub- classifications was not ...human breast is ...human breast. However, ER and PR become correlated in breast ... See full document
10
<p>EGFR Promotes the Development of Triple Negative Breast Cancer Through JAK/STAT3 Signaling</p>
... all breast cancer patients are diagnosed with primary triple negative breast cancers ...typically associated with a large size, higher grade, lymph node involvement at diagnosis ... See full document
15
High expression of NR1D1 is associated with good prognosis in triple negative breast cancer patients treated with chemotherapy
... We used immunohistochemistry to analyze NR1D1 ex- pression in primary invasive breast cancer specimens. A total of 694 patients who had informative immunohisto- chemical results were included in this study. ... See full document
8
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.
... Figure 5 The pan–PIM kinase inhibitor AZD1208 impairs clonogenic survival and reduces tumor growth in in vivo xenograft models of TNBC.(a,b) Clonogenic survival and growth of MDA-MB-231, SUM159, SUM149 and MTSV1.7 cells ... See full document
31
Original Article Expression of ALDH1, MACC1, and KAI1 in the triple-negative breast cancer and their clinical significance
... “normal” breast tissues were collected from the Department of Pathology, the First Affiliated Hospital of Bengbu Medical College (China), from January 2008 to December ...preoperative chemotherapy or ... See full document
10
Original Article Therapeutic effects of epirubicin combined with capecitabine for patients with triple negative breast cancer
... Breast cancer is the most common malignant tumor in ...with breast cancer in the world in 2018, accounting for ...female cancer incidence. Deaths of female patients with breast ... See full document
10
Original Article Expression of miR-146a in triple negative breast cancer and its clinical significance
... against breast cancer is chosen mainly based on different histological types, and clinical/pathological grades of tumors, including surgery, radio/chemotherapy, targeted therapy and hormone ... See full document
6
Identifying Biomarkers to Pair with Targeting Treatments within Triple Negative Breast Cancer for Improved Patient Stratification.
... in the neoadjuvant setting can improve response rates in women with triple negative breast cancer 201. [35-38][r] ... See full document
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