[PDF] Top 20 Original Article Ligustrazine attenuates LPS-induced endothelial dysfunction by inhibiting NF-κB pathways
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Original Article Ligustrazine attenuates LPS-induced endothelial dysfunction by inhibiting NF-κB pathways
... of LPS- induced NF-κB activation cannot be ignored in bacterial ...signal pathways, fol- lowing the activation of the proinflammatory transcription factor NF-κB [26], ... See full document
7
Original Article The ginsenoside Rd suppresses LPS-induced inflammation and NF-κB activation in colon cancer cells
... G-Rd attenuates LPS-induced inflammation by inhib- iting the expression of iNOS and COX-2 via the degradation of NF-κB ...of NF-κB activation in LPS-stimulated ... See full document
12
Original Article Matrine attenuates high glucose-induced podocyte damage by inhibiting HMGB1-associated TLR4-NF-κB signaling
... arthritis [25, 39], in rats with early brain injuries after experimental subarachnoid hemorrhages [40], in mice with airway inflammation [26], and in mice with LPS-induced acute lung injuries [27, 41]. TLR4 ... See full document
10
Original Article Methane attenuates LPS-induced acute lung injuries by inhibiting inflammation and oxidation in mice
... of LPS-induced acute lung inju- ries, this study further detected pro-inflamma- tory cytokine and chemokine changes in the air space and lung parenchyma between the MS group and LPS group, 24 hours ... See full document
10
Fasudil Attenuates LPS-Induced Acute Lung Injury by Preventing Endothelial Dysfunction
... ameliorate LPS-induced acute lung injury (ALI) in mice, but the mechanism remains ...and endothelial apoptosis were determined to evaluate the effects of fasudil on lung ...microvascular ... See full document
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Original Article MicroRNA-9500 attenuates TNF-induced endothelial cells inflammatory damage through inhibition of NF-κB signaling pathway
... in endothelial cells (ECs) but the mechanism at post-transcription- al levels is not fully ...The NF-κB signaling pathway is involved in TNF-induced chronic EC inflammation was ...and ... See full document
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Original Article Da-Cheng-Qi Decoction attenuates inflammatory response and apoptosis via inhibiting NF-κB and PUMA mediated signaling pathways in acute pancreatitis
... was induced by infusion of the taurocholate into pancreatic duct of ...ELISA. NF-κB activity of pancreas was detected by EMSA. NF-κB p65, PUMA and activated caspase-3 was detected by ... See full document
8
Original Article Sarcandra glabra attenuates LPS-induced acute lung injury via inhibiting inflammation in rats
... (ALI) induced by LPS in ...on LPS-induced ALI and the underlying ...attenuated LPS-induced lung injury in rats, which was manifested by the improvement of histological ... See full document
9
Original Article Pitavastatin attenuates atherosclerosis by suppressing NF-κB signaling in a high-cholesterol diet plus balloon catheter injury rabbit model
... by inhibiting the onset and progression of AS ...vein endothelial cells by up- regulating eNOS production ...inhibits NF-κB activation in hepato- cellular carcinoma cells ...via ... See full document
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Original Article Bisabolol attenuates sepsis-induced acute lung injury through inhibiting NF-κB-mediated inflammatory response
... As an anti-inflammatory agent, a number of previous studies indicated that bisabolol could inhibit the LPS-induced NO and iNOS expres- sion by blocking the NF-κB signaling path- way (19). Our ... See full document
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Original Article Ruscogenin exerts beneficial effects on monocrotaline-induced pulmonary hypertension by inhibiting NF-κB expression
... the endothelial-protective effects and the possible anti-inflammatory mechanism of ruscogenin is associated with the suppres- sion of intercellular adhesion molecule-1 (ICAM- 1) expression in endothelial ... See full document
8
Original Article Activation of sonic hedgehog signaling attenuates oxidized low-density lipoprotein-stimulated brain microvascular endothelial cells dysfunction in vitro
... induces endothelial cells dysfunction through various signal path- ways, such as activation of NF-κB [21], GSK3β/ β-catenin [22], mitochondrial-dependent apop- totic pathway [9] and ... See full document
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Original Article miR-27a protects against acute lung injury in LPS-treated mice by inhibiting NF-κB-mediated inflammatory response
... of NF-κB function may be useful for protection of ALI ...(RvD1) attenuates lung inflam- mation of LPS-induced acute lung injury by sup- pressing NF-κB activation ... See full document
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Original Article Aspirin-triggered lipoxin A4 attenuates lipopolysaccharide-induced acute lung injury by inhibiting activation of mitogen-activated protein kinases and NF-κB in mice
... exercise- induced bronchoconstriction in children asth- ma [15, ...off LPS-induced severe inflammation in ALI in mice and its mechanism ...Intratracheal LPS induces severe leukocyte ... See full document
9
Original Article Dexmedetomidine ameliorates lipopolysaccharide-induced endothelial barrier disruption and inflammation by inhibiting NF-κB activity and activating α2-adrenergic receptor
... the endothelial barri- er is breakdown, leading to loss of selective permeability and vascular leakage that may eventually result in shock ...that LPS can induce barrier dis- ruption in endothelial ... See full document
8
Original Article Hsp90 protects LPS induced pancreatic inflammation of AR42J cells by inhibition of p38MAPK/NF-κB pathways
... Hsp90 inhibiting the inflammatory response in AR42J ...protect LPS induced pancreatic inflam- mation of AR42J cells by inhibition of p38MAPK/ NF-κB ... See full document
7
Hyperin protects against LPS-induced acute kidney injury by inhibiting TLR4 and NLRP3 signaling pathways
... on LPS-induced AKI in ...TLR4, NF-κB, and NLRP3 were detected by western blot ...inhibited LPS-induced TNF-α, IL-6, and IL-1β ...Furthermore, LPS-induced TLR4 ... See full document
7
Original Article Exendin-4 attenuates high glucose-induced endothelial progenitor cells dysfunction through the PI3-K/Akt/eNOS pathway
... eNOS activation were investigated in cultured EPCs exposed to high glucose. As shown in Figure 3A, high glucose reduced NO production of EPC by 35%, yet treatment with exendin-4 reversed NO production by 27%. Moreover, ... See full document
7
Original Article Punicalagin inhibits RANKL-induced osteoclastogenesis by suppressing NF-κB and MAPK signaling pathways
... to NF-κB and MAPKs activa- tion, including c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase 1/2 (ER- K1/2), and p38 [9, ...osteoclastogenesis- induced bone ... See full document
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Original Article TSLP induced by estrogen stimulates secretion of MCP-1 and IL-8 and growth of human endometrial stromal cells through JNK and NF-κB signal pathways
... TSLP induced by estrogen possible down- regulates the expression of NME1, and further modulates the biological behavior of ...tion induced by TSLP, in view of the key role of several signals in cell growth, ... See full document
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