[PDF] Top 20 Original Article Prognostic implications of adhesion molecule expression in colorectal cancer

... CD44 expression and the prognosis of patients with CRC ...CD44s expression is a sensitive marker for lymph node metasta- sis in CRC ...CD44s expression is an independent predictor of overall survival ... See full document

... β-catenin was originally identified as a mem- brane component of the cadherin-mediated cell-cell adhesion system and it is now widely recognized as a critical element of the Wnt sig- nal pathway [37]. In the ... See full document

... CDX2 expression based on the human CRC tissues; (2) publications in English language; (3) studies reported the association between CDX2 expression level and CRC prognosis; and (4) studies with the hazard ... See full document

... have established that Gab proteins promote human tumorigenesis by functioning as “accomplices” of certain oncoproteins or by amplifying signaling upon the overexpression of Gab proteins. Similar to the Gab proteins, Gab2 ... See full document

... lation with tumorigenesis because of its location at fragile sites or cancer-associat- ed regions of the genome [16]. It has been revealed by previous studies that circulat- ing miRNAs are not only derived from ... See full document

... liver cancer [10], prostate cancer [11], bladder cancer [12], lung cancer [13] and CRC ...the prognostic value of PKM2 in CRC remains largely ... See full document

... surface adhesion molecules (CAM) that regulate via intercellular and cell-matrix signaling various cellular processes including wound healing, cell differentiation, division, growth, migration and metastatic ... See full document

... A total of 96 cases of CRC tissues and another 20 paired of CRC tissues and corresponding adjacent normal tissues were collected from the Department of Pathology and Department of Surgery of Jinling Hospital between ... See full document

... Colorectal cancer (CRC) is the second most commonly diagnosed cancer in the world [16, ...17]. Colorectal cancer mortality has decreas- ed by 39% in United States in the past two ...of ... See full document

... for colorectal cancer ...and prognostic role of serum miR-206 in ...miR-206 expression was closely associated with TNM stage and lymph node ...independent prognostic indicator for ... See full document

... Surprisingly, activation of P2X7R may reveal contrary effects in cancer cells according to dif- ferent environmental conditions and various factors. It may show a pro-tumoral effect in some conditions and an ... See full document

... signalling molecule in epithet- lial cells through cholinergic receptors such as nAChR or muscarinic (mAChR) ...in expression and localization of intestinal tight and adherens junction ...cell ... See full document

... membranous expression might be a predictive factor of colorectal tumor ...branous expression might be useful for prog- nostic prediction and treatment selection in early colorectal ... See full document

... Epithelial-mesenchymal transition (EMT) is thought to be one of the main mechanisms of metastasis in various cancers [3, 4]. EMT is a highly conserved program that converts immo- tile, polarized epithelial cells into ... See full document

... the expression level of L1CAM protein in breast cancer cells transfected with either L1CAM- targeting siRNA (si-L1CAM) or nontargeting con- trol siRNA ... See full document

... MTA2 expression with presence, development, metastasis and prognosis of colorectal cancer (CRC) was ...of cancer tissues and the adjacent tissues. Subsequently, the expression of MAT2 ... See full document

... Abstract: Colorectal cancer is the third most frequently diagnosed malignancy, and the prognosis at advanced tumor stages remains ...in colorectal cancer. The expression levels of Ki67, ... See full document

... lung cancer, ovarian cancer and gastric cancer. In colorectal cancer (CRC), SMYD3 is proved to stimulate the proliferation of cancer cells, but the clinical significance of SMYD3 ... See full document

... der cancer [18]. Zheng et al. found that that UCA1 expression was remarkably increased in gastric cancer tissues and cell lines compared with that in the normal ...UCA1 expression correlated ... See full document

... in colorectal cancer at both mRNA and protein ...LSF expression in colorectal cancer, we analyzed the relationship between expression of LSF and clinicopathologic ... See full document