[PDF] Top 20 Original Article SATB2 induces stem-like properties and promotes epithelial-mesenchymal transition in hepatocellular carcinoma

... a mesenchymal phenotype [16]. Downregulation of SATB2 is sufficient to induce EMT and pro- mote migration and invasion in non-small cell lung cancer cells ...of SATB2 significantly up-regulated the ... See full document

... in hepatocellular carcinoma tissues compared with normal liver tissue (Figure ...TCGA hepatocellular carcinoma samples ...axis promotes the malignant progression of patients with HCC, ... See full document

... LPS/TLR4 induces cells EMT through activation of NF- ...EMT, epithelial- mesenchymal transition; HCC, hepatocellular carcinoma; LPS, lipopolysaccharide; NF- B nuclear factor ... See full document

... of epithelial cells to mesenchymal cells under normal physiological or speci fi c pathological ...of epithelial markers (such as E-cadherin and β -catenin) and up- regulation of mesenchymal ... See full document

... To determine how OPN to induce EMT, a combination of co-IP and MS was used to identify the interactome of OPN in Hep3B-OPN and Hep3B control cells. Flag-OPN produced in Hep3B cells was immunoprecipitated by anti-Flag mAb ... See full document

... curative resection with informed consent between 2007 and 2010 at the First Affiliated Hospital of Dalian Med- ical University. All tissues were collected immediately upon resection of the tumors in the operation ... See full document

... Residual tumor progression after insufficient RFA has been recently reported and two possible mechanisms also have been proposed. RFA may alter tumor microenviron- ment to enhance the outgrowth of residual tumor cells. ... See full document

... primary carcinoma by promoting invasion and metastasis ...the properties of self-renewing stem ...and stem cell properties ...cancer stem cells in primary human gastric tumors ... See full document

... knockdown induces the epithelial- mesenchymal transition and promotes migra- tion and invasion in SK-Hep-1 cells and HepG2 cells ... See full document

... tumor-initiating properties in ...cancer stem cell-like proper- ties ...of epithelial markers such as E-cadherin and up-regulation of mesenchymal markers like ... See full document

... Holliday Junction Recognition Protein (HJURP) is involved in various cancers including hepatocellular carcinoma (HCC). Current studies have showed that HJURP is correlated with HCC proliferation. However, ... See full document

... LncRNA AFAP1-AS1 was derived from the anti- sense strand of DNA at the coding gene locus of AFAP1 which can regulate actin filament integrity and act as an adaptor protein linking Src family members and other signaling ... See full document

... just like transcriptional noise which plays an important role in generating phenotypic heterogeneity (120,121), the collective effect of conformational noise is an ensemble of protein regulatory network ... See full document

... cell carcinoma [16], colon cancer [17], medulloblastoma [18], gastric cancer [19] and pancreatic carcinoma ...regulating epithelial-mesenchymal transition (EMT) through the GLI1 ... See full document

... an epithelial to mesen- chymal phenotype, marked by the decreased expression of E-cadherin, and increased expre- ssion of N-cadherin, vimentin, and cellular pro- teases ... See full document

... E-cadherin is a phenotypic membranous adhesion molecule on epithelial cells. It has been proved to be involved in proliferation, migration and the process of EMT, keeping cells in a quiescent, non-motile state. ... See full document

... [8] Zhao S, Bellone S, Lopez S, Thakral D, Schwab C, English DP, Black J, Cocco E, Choi J, Zam- mataro L, Predolini F, Bonazzoli E, Bi M, Buza N, Hui P, Wong S, Abu-Khalaf M, Ravaggi A, Big- notti E, Bandiera E, Romani ... See full document

... lens epithelial cells have a close relationship with the formation of ...cell mesenchymal mode movement [16, 17] and deletion of RAC1 was reported to inhibit cell migration and wound healing of epidermal ... See full document

... Cervical carcinoma is one malignant tumor that severely affects the female’s ...[3]. Epithelial mesenchymal transition (EMT) existed in epi- thelial derived malignant tumor, and mainly in ... See full document

... One key feature of EMT is the downregulation of E-cadherin, a cell adhesion molecule that pres- ents in the membrane of normal epithelial cells. E-cadherin binds to β-catenin to form a protein complex that is ... See full document