[PDF] Top 20 Overgrowth of human synovial cells driven by the human T cell leukemia virus type I tax gene
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Overgrowth of human synovial cells driven by the human T cell leukemia virus type I tax gene
... established synovial cell clones (SCCs) from three HTLV-I carriers who demonstrated synovial overgrowth but were otherwise ...the tax gene exhibited high levels of ... See full document
9
Evidence for Cooperative Transforming Activity of the Human Pituitary Tumor Transforming Gene and Human T-Cell Leukemia Virus Type 1 Tax
... plus Tax enhances cellular ...PTTG, Tax, and PTTG plus Tax in G418-selected NIH 3T3 clones. Whole-cell lysates from NIH 3T3 neo (lane 1), NIH 3T3 Tax-neo (lane 2), NIH 3T3 PTTG-neo ... See full document
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Immortalization of T Lymphocytes by Human T-Cell Leukemia Virus Type 1 Is Independent of the Tax-CBP/p300 Interaction
... by Tax occurs through interactions of Tax with CREB and the CREB response elements (CREs) found in three 21-nucleotide repeats in the LTR (2, 11, 55, 61, ...of Tax with C-G-rich motifs that flank the ... See full document
5
Regulation of expression driven by human immunodeficiency virus type 1 and human T-cell leukemia virus type I long terminal repeats in pluripotential human embryonic cells.
... 1398 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Human pluripotential embryonic teratocarcinoma cells differentially expressed gene activity controlled by the human[r] ... See full document
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Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV 1) tax protein or virus transformed cells
... in tax transformed cells resulted from high expression of ...Balb/c3T3 cells using a supernatant from the B line, which was associated with induction of cell ...infected human T ... See full document
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Induction of Lactoferrin Gene Expression in Myeloid or Mammary Gland Cells by Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax: Implications for Milk-Borne Transmission of HTLV-1
... neighboring cells in a paracrine ...lactoferrin-producing cells, such as neutrophils and mammary epithelial cells, are not known as typical target cells of ...HTLV-1-infected T ... See full document
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Upregulation of Human T-Cell Leukemia Virus Type 1 Antisense Transcription by the Viral Tax Protein
... Human T-cell leukemia virus type 1 (HTLV-1) is the etio- logical agent of adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy, also known ... See full document
7
Constitutive phosphorylation and turnover of I kappa B alpha in human T-cell leukemia virus type I-infected and Tax-expressing T cells.
... Jurkat cells following PMA treatment for times ranging from 0 to 60 min ...above I k B a was detected immediately after PMA addition to MT-2 cells ...MT-2 cells, indicating a constitutive ... See full document
6
Silencing of human T cell leukemia virus type I gene transcription by epigenetic mechanisms
... Human T-cell leukemia virus type I (HTLV-I) is associated with a neoplastic disease, adult T-cell leukemia (ATL), and inflammatory diseases, ... See full document
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Localization of human T-cell leukemia virus type 1 tax to subnuclear compartments that overlap with interchromatin speckles.
... of Tax in speckled com- plexes, splicing-competent nuclear extracts were made from HeLa cells, Tax-transfected HeLa cells, and HTLV-1-trans- formed C8166-45 ...whether Tax would ... See full document
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Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins.
... All constructs containing the HIV-1 direct repeats proved inducible in the Jurkat tax-9 cell line but not in the Jurkat anti-tax-10 cell line, suggesting that the observed induction of t[r] ... See full document
9
Mutational analysis of human T-cell leukemia virus type 2 Tax.
... Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) contain at least two trans-regulatory genes, tax and rex (23, 27, 39, ...Both Tax and Rex ... See full document
6
Human T-Cell Leukemia Virus Type 1 Expressing Nonoverlapping Tax and Rex Genes Replicates and Immortalizes Primary Human T Lymphocytes but Fails To Replicate and Persist In Vivo
... identified Tax or Rex mutants with defective activities or impaired biochemical properties that are associated with protein ...example, Tax mutants that specifically diminish the protein’s ability to acti- ... See full document
9
Human T cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules
... Human T-cell leukemia virus type I (HTLV-I) is a retrovi- rus responsible for adult T-cell leukemia (ATL) [1] and a chronic neurological ... See full document
10
Prevention of Adult T-Cell Leukemia-Like Lymphoproliferative Disease in Rats by Adoptively Transferred T Cells from a Donor Immunized with Human T-Cell Leukemia Virus Type 1 Tax-Coding DNA Vaccine
... Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) in infected individuals after a long incubation ...tumor cells, as well ... See full document
7
Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene.
... Radiation resulted in no significant change in latency for three Thy-tax lines, for the LTR-tax line, or for double transgenic offspring compared with the median 159 days of latency seen[r] ... See full document
5
Influence of human T-cell leukemia virus type I tax and rex on interleukin-2 gene expression.
... 67, 1993 HTLV-I tax AND rex INFLUENCE ON IL-2 GENE EXPRESSION structs also confirm this observation, because expression of tax and rex in those experiments is promoted by the HTLV-I DISC[r] ... See full document
10
Identification of Poly(ADP-Ribose) Polymerase as a Transcriptional Coactivator of the Human T-Cell Leukemia Virus Type 1 Tax Protein
... Human T-cell leukemia virus type 1 (HTLV-1) encodes a transcriptional activator, Tax, whose activity is believed to contribute significantly to cellular ...transformation. ... See full document
9
Effect of human T-cell leukemia virus type I tax protein on activation of the human vimentin gene.
... Analysis of the -241- to - 140-bp region: localization of an Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest a Human vimentin promoter-CAT fusion plasmids having variou[r] ... See full document
8
Human T cell leukemia virus type I Tax induces the expression of CD83 on T cells
... The medium used throughout was RPMI 1640 medium (Sigma-Aldrich. Inc., St. Louis, MO, USA) supplemented with 10% fetal calf serum (FCS), 100 U/ml penicillin and 100 µg/ml streptomycin (hereinafter called RPMI medium). ... See full document
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