[PDF] Top 20 Pathogenesis of Influenza A (H5N1) Virus Infection in a Primate Model
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Pathogenesis of Influenza A (H5N1) Virus Infection in a Primate Model
... 1997, influenza A viruses of the H5N1 subtype were isolated from patients in the Hong Kong area (3, 5, ...avian influenza viruses that had caused mass mortality in chicken farms in the same area (3, 14, 22, ... See full document
5
Pathogenesis of Avian Influenza (H7) Virus Infection in Mice and Ferrets: Enhanced Virulence of Eurasian H7N7 Viruses Isolated from Humans
... A/PR/8/34 virus (30) or with highly pathogenic H5N1 viruses ...to influenza virus ...H5N1 virus infection in mice (44), and the local synthesis of TNF- ␣ within the brain may lead to ... See full document
9
Pathogenesis and transmissibility of highly (H7N1) and low (H7N9) pathogenic avian influenza virus infection in red-legged partridge (Alectoris rufa)
... avian influenza virus by a competition ELISA test (ID-VET, Montpellier, France) and a specific hemagglu- tination inhibition (HI) test for the H7 ... See full document
9
Pathogenesis of 1918 Pandemic and H5N1 Influenza Virus Infections in a Guinea Pig Model: Antiviral Potential of Exogenous Alpha Interferon To Reduce Virus Shedding
... enza virus infection (reviewed in reference ...mammalian model used for influenza virus re- search, the mouse, is not susceptible to infection with un- adapted human ... See full document
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Involvement of the different lung compartments in the pathogenesis of pH1N1 influenza virus infection in ferrets
... pH1N1 infection are consequence of interstitial pneumonia triggered by alveolar viral replication and an exacerbated host immune response, characterized by the up-regulation of pro-inflammatory cytokines and the ... See full document
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Dependence on O2 generation by xanthine oxidase of pathogenesis of influenza virus infection in mice
... modified superoxide dismutase (a scavenger of O2-) improved the survival rate of influenza virus-infected mice. These results indicate that generation of oxygen-free radicals by XO, coupled with catabolic ... See full document
8
Influenza A Virus PB1-F2 Protein Contributes to Viral Pathogenesis in Mice
... mutant virus recov- ered, while mice in the wt group succumbed to the ...since influenza virus infection is associ- ated with development of immunopathology, which can be- come irreversible ... See full document
8
Galectin-1 Binds to Influenza Virus and Ameliorates Influenza Virus Pathogenesis
... to influenza virus infection than wild- type mice, resulting in death in five of six mice, whereas only one of six wild-type mice died after viral ...of influenza virus-infected mice by ... See full document
11
[18F]-Fluorodeoxyglucose Uptake in Lymphoid Tissue Serves as a Predictor of Disease Outcome in the Nonhuman Primate Model of Monkeypox Virus Infection
... when lymphadenopathy was minimal. Detailed statistical analysis was performed and reported previously (8). On day 7 p.i., necropsied LN tissues from moribund NHPs had high levels of edema and lymphoid necrosis and ... See full document
13
Syrian Hamster as an Animal Model for the Study of Human Influenza Virus Infection
... influenza virus transmission ...animal model for influenza ...influenza virus (10), the A(H1N1) pandemic 2009 [A(H1N1)pdm09] virus (6, 11), and H7N9 viruses (8, ...a model of transmission ... See full document
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Prophylactic Administration of Bacterially Derived Immunomodulators Improves the Outcome of Influenza Virus Infection in a Murine Model
... in influenza virus-infected mice ...against influenza virus, respiratory syncytial virus (RSV), and Cryptococcus neoformans infections ...animal model studies are warranted ... See full document
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Pathogenesis of Hepatitis C Virus Infection in Tupaia belangeri
... non- primate mammal indigenous to certain areas of Southeast Asia ...to infection with a wide range of human- pathogenic viruses, including hepatitis B viruses (13, 20, 31), and appears to be permissive for ... See full document
9
Infection of Calves with Bovine Norovirus GIII.1 Strain Jena Virus: an Experimental Model To Study the Pathogenesis of Norovirus Infection
... Immunoperoxidase staining. JV antigen was detected in paraffin sections collected on charged slides by the indirect immunoperoxidase method. The monoclonal antibody (MAb) CM39, which recognizes an epitope on the capsid ... See full document
9
Age-Associated Differences in Infection of Human Skin in the SCID Mouse Model of Varicella-Zoster Virus Pathogenesis
... VZV infection, human fetal skin grafts had the characteristics of healthy skin tissue that we have observed previously (23, 25), as shown in representative sections ... See full document
15
Latent Adeno-Associated Virus Infection Elicits Humoral but Not Cell-Mediated Immune Responses in a Nonhuman Primate Model
... in the interphase nuclei in every case, however, one would not expect the examination of such a small number of metaphase spreads (five or fewer per sample) to show integration even if it occurred in every case where AAV ... See full document
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Deletion of the Monkeypox Virus Inhibitor of Complement Enzymes Locus Impacts the Adaptive Immune Response to Monkeypox Virus in a Nonhuman Primate Model of Infection
... MPXV-Z, infection of RM with D14L KO MPXV-Z re- sulted in more severe disease than WT MPXV-Z ...any infection being detected in the single D14L KO MPXV-Z- infected animal that succumbed to MPXV-related ... See full document
16
Molecular mechanism of complex infection by bacteria and virus analyzed by a model using serratial protease and influenza virus in mice.
... We conclude that this major serratial exoprotease has a deleterious effect on mice infected with influenza virus and that this effect seems to result from enhancement of viral growth by [r] ... See full document
8
Effects of Aging on Influenza Virus Infection Dynamics
... of influenza virus in aged mice may lead to limited activation of the acquired immune system, which ultimately leads to slow viral ...the virus could be directly related to the large number of ... See full document
9
Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI
... (Figure 7, A and B, Supplemental Figure 8A), suggesting a model in which TACI signaling in innate cell subsets indirectly regulates ASC differentiation and survival. Of note, whole body irradiation used in this ... See full document
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Animal Models of Zika Virus Infection, Pathogenesis, and Immunity
... (i) Pathogenesis in immunocompetent adult ...and pathogenesis (38, ...ZIKV infection in pregnant and nonpregnant rhesus, cynomolgus, and pigtail ...ZIKV infection of rhesus macaques (38, 87, ... See full document
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