[PDF] Top 20 5 Phenyl 2 (4 pyridyl)pyrimidine
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5 Phenyl 2 (4 pyridyl)pyrimidine
... Symmetry codes: (i) x; y þ 2; z þ 2; (ii) x þ 1; y þ 1; z þ 2; (iii) x 1; y; z; (iv) x; y þ 1; z þ 2; (v) x þ 1; y þ 2; z þ 2; (vi) x þ 1; y; z. Cg1 is the centroid of the ... See full document
11
4 Amino 2 chloro 5 nitro 6 (propylamino)pyrimidine
... interaction between the ortho propylamine and the nitro groups (Table 2, Fig. 2). This complex hydrogen-bonding pattern results in the formation of polymeric chains of coplanar molecules, which lie ... See full document
10
2 Phenyl 4 (p toluidinomethylene) 5 oxazolone
... shows a partial double-bond character. This may be due to the delocalization of the lone pair of electrons of the N atom over the N7ÐC6 C4 moiety (Thiruvalluvar & Parthasarathi, 1995). The exocyclic bond angles ... See full document
11
2 Phenyl 5 (p tolyl) 1,3,4 oxadiazole
... F 2 against ALL ...F 2 , convention- al R-factors R are based on F, with F set to zero for negative F 2 ...F 2 > σ(F 2 ) is used only for calculating R- factors(gt) ...F 2 are ... See full document
11
Ethyl 7 methyl 2 phenylpyrazolo[1,5 a]pyrimidine 5 carboxylate
... Pyrazolo[1,5-a]pyrimidines have attracted considerable interest because of their biological activity. For instance, they are known for their potent utility as selective peripheral benzodiazepine receptor ligands (Selleri ... See full document
8
Methyl {2 [(3 phenyl 1,2,4 oxadiazol 5 yl)methoxy]phenyl}acetate
... 1,2,4-Oxadiazole derivatives are of great interest because of their biological properties. Some derivatives of 1,2,4-oxa- diazoles have intrinsic analgesic (Terashita et al., 2002), anti- in¯ammatory (Nicolaides et al., ... See full document
8
7 Chloro 5 methyl 2 phenylpyrazolo[1,5 a]pyrimidine
... The crystal structure of the title compound is built up from two fused five and six-membered rings (N1/N2/C4–C6 and N1/N3/C1–C4) linked to a methyl group and to a phenyl ring (C7–C12) as shown in Fig. 1. The ... See full document
6
Ethyl (2Z) 2 (2 chlorobenzylidene) 7 methyl 3 oxo 5 phenyl 2,3 dihydro 5H 1,3 thiazolo[3,2 a]pyrimidine 6 carboxylate
... Fused pyrimidines are pharmacologically interesting hetero- cyclic systems with remarkable biological activities such as antiviral, anticancer, anti-inflammatory and antihypertensive properties (Kappe, 2000; Rovnyak et ... See full document
9
Synthesis of aryl {4 [({5 [3 (methylsulfonyl)phenyl]pyrazin 2 yl} oxy)methyl]piperidin 1 yl}methanones
... synthesize 2-(piperidin-4- ylmethoxy) pyrazines derivatives by the condensation of 2-[3-(methylsulfonyl) phenyl]-5-(piperidin-4-ylmethoxy) pyrazine with various aromatic acid chlorides in the ... See full document
11
Ethyl 3 ethoxycarbonylmethyl 7 methyl 5 phenyl 5H thiazolo[3,2 a]pyrimidine 6 carboxylate
... ring incorporating a chiral C atom is significantly puckered and adopts a slight boat conformation with C atom bearing the phenyl ring and the N atom opposite displaced by 0.367 (2) and 0.107 (2) A ˚ ... See full document
8
Ethyl 2 (5 phenyl 1,3,4 oxadiazol 2 ylsulfanyl)acetate
... the phenyl and the oxadiazole rings of the adjacent molecules is 3.846 (2) Å which indicates the existence of π-π stacking ...Ethyl ... See full document
6
SYNTHESIS AND ANTIMICROBIAL EVALUATION OF 2 (4 FLUORO BENZYLTHIO) N (SUBSTITUTED PHENYL)PYRIMIDINE 4 AMINES
... of 2-(4-fluorobenzylthio)-N- (substituted phenyl)pyrimidine-4-amines (4a-k): To a solution of 2-(4-fluorobenzylthio)-4- chloropyrimidine (3) ... See full document
7
In-vitro Antimicrobial and Antifungal Activity of Pyrimidine and Pyrazolo-[1, 5-a] Pyrimidine
... pyrazolo-[1, 5-a] pyrimidines and pyrimidine amine as antimicrobial agents have been successfully ...pyrazolo-[1, 5-a] pyrimidines and pyrimidine amine exhibited promising antibacterial and ... See full document
5
5 [(5 Methylthiazol 2 yl)diazenyl]pyrimidine 2,4,6(1H,3H,5H) trione
... In the crystal structure of compound (II), with methyl groups in positions 1 and 3, intermolecular N—H N hydrogen bonds from the exocyclic NH function toward the thiazole N atom link the molecules into centrosymmetric ... See full document
7
Raltegravir monohydrate
... methyl 2-(2-{[(benzyloxy)carbonyl]amino}propan-2-yl)- 5-hydroxy-6-methoxy- pyrimidine-4-carboxylate (Shang, Qi et ...methyl ... See full document
10
ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF 2-(4-FLUOROBENZYLTHIO)-N-(SUBSTITUTED PHENYL) PYRIMIDINE-4-AMINES
... chemistry. Pyrimidine derivatives have been reported to possess a variety of pharmacological activities, notable among are the antibacterial 1 , antihypertensive 2 , ... See full document
5
3 Phenyl 5 (2 thienyl) 2 pyrazoline 1 thioamide
... It has been reported (Krishna et al., 1999) that the N—N bond length in the pyrazoline ring varies over a wide range, from 1.234 (8) to 1.385 (4) A ˚ . In compound (I), the N1—N2 distance is even longer, 1.394 (2) ... See full document
7
1 {[5 Fluoro 2 (trifluoromethyl)phenyl]iminomethyl} 2 naphthol
... Schiff base ligands have significant importance in chemistry, especially in the development of Schiff base complexes (Johnson et al., 1996; Alizadeh et al.,1999; Wang & Zheng, 2007). Schiff bases that have ... See full document
7
(Z) Ethyl 2 (2,4 dimethylbenzylidene) 7 methyl 3 oxo 5 phenyl 3,5 dihydro 2H thiazolo[3,2 a]pyrimidine 6 carboxylate
... C14 0.0442 (14) 0.0568 (14) 0.0743 (16) −0.0075 (12) 0.0021 (12) 0.0128 (12) C15 0.0662 (18) 0.104 (2) 0.0741 (17) −0.0152 (16) 0.0208 (14) 0.0375 (16) C16 0.136 (3) 0.149 (3) 0.0596 (17) −0.023 (3) 0.036 ... See full document
8
2 (5 Methyl 1,3,4 oxadiazol 2 yl)phenyl acetate
... diazole rings are approximately coplanar, with an inter-ring dihedral angle of 4.14 (2)°, while the ester plane defined by O1, O2, C13, C14 is rotated out of the benzene plane giving a dihedral angle of 82.69 (9)° ... See full document
6
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