[PDF] Top 20 Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial
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Phenylephrine versus norepinephrine for initial hemodynamic support of patients with septic shock: a randomized, controlled trial
... hand, phenylephrine could be preferable over norepine- phrine, since β 1 -receptor stimulation may increase the heart rate and myocardial oxygen ...either norepinephrine or phenylephrine in terms of ... See full document
11
Targeted tissue perfusion versus macrocirculation guided standard care in patients with septic shock (TARTARE 2S): study protocol and statistical analysis plan for a randomized controlled trial
... study patients are care- fully monitored and re-evaluated, and treatment goals are registered every ...study patients will be better and safer than the highly varying standard clinical practice; ... See full document
13
Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo controlled trial in septic shock patients
... of patients weaned off norepinephrine during the first 24 h, and decreased the mean cumulative dose of nor- epinephrine, thus demonstrating rapid onset and sus- tained ...many patients were out of ... See full document
10
Polymyxin B hemoperfusion: a mechanistic perspective
... EUPHRATES trial (Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized Controlled Trial of Adults Treated for Endotoxemia and Septic Shock; Clin- ...blinded, ... See full document
8
Residual rates of mortality in patients with severe sepsis: a fatality or a new challenge?
... and septic shock published during the past decade have failed to reveal the superiority of any therapeutic intervention on mortality compared with evolving standards of care, with the exception of the ... See full document
6
Balanced crystalloids versus isotonic saline in critically ill patients: systematic review and meta-analysis
... the patients in each study arm still could have received the other fluid type either before enrollment especially in the operation rooms or in the emergency department or during the study and this factor could ... See full document
7
Alkaline phosphatase for treatment of sepsis induced acute kidney injury: a prospective randomized double blind placebo controlled trial
... or septic shock, the remarkable consistency of findings in this trial (attenuation of urinary excretion of markers of renal damage and improved clinical outcomes), and in the previous trial in ... See full document
12
Gastric tonometry versus cardiac index as resuscitation goals in septic shock: a multicenter, randomized, controlled trial
... [2] versus the negative Ital- ian multicenter [3] ...including patients after up to 48 hours of ICU ...period, patients may have been exposed to prolonged hypoperfusion before being ...ill ... See full document
7
Terlipressin for septic shock patients: a meta-analysis of randomized controlled study
... less norepinephrine require- ment, improved hemodynamic status and more creatinine clearance during septic shock therapy ...vasodilatory shock looked into a sub- group of terlipressin ... See full document
9
Clinical trials comparing norepinephrine with vasopressin in patients with septic shock: a meta-analysis
... Methods: PubMed, EMBASE, and the Cochrane Library database were searched from database inception to December 2013. We selected randomized controlled trials in adults with septic shock and ... See full document
7
Echocardiogram-guided resuscitation versus early goal-directed therapy in the treatment of septic shock: a randomized, controlled, feasibility trial
... citate septic shock patients without administering harmful amounts of IV fluid or failing to provide adequate support for organ ...guiding hemodynamic man- agement to improve outcomes ... See full document
8
Levosimendan for resuscitating the microcirculation in patients with septic shock: a randomized controlled study
... the patients were treated with dobutamine as an active comparator at a dose of 5 μg/kg per minute) varies from the study of De Backer and colleagues [2], who reported that the same dose of dobutamine increased ... See full document
11
Effects of vasopressinergic receptor agonists on sublingual microcirculation in norepinephrine dependent septic shock
... Interestingly, we observed a time-dependent improve- ment in some microcirculatory variables in all study groups. The beneficial evolution in the NE group over time is in agreement with a recent study by Boerma et al. ... See full document
10
Early versus delayed administration of norepinephrine in patients with septic shock
... to initial antimicrobial treatment was not significantly different between the Early-NE group and the Late-NE group, it was significantly longer in the non-survivor group than the survivor group and it is a ... See full document
8
Bench to bedside review: The initial hemodynamic resuscitation of the septic patient according to Surviving Sepsis Campaign guidelines – does one size fit all?
... the initial hemodynamic management of severe sepsis or septic shock [10] (Table ...for hemodynamic support of sepsis which recommend filling pressures of between 12 and 15 mm Hg ... See full document
5
Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine
... in patients with sepsis [15-17,19,20]; however, we cannot exclude the pos- sibility that our study was underpowered to detect differ- ences in important ...that patients in the vasopressin group were also ... See full document
10
Effect of Music Therapy on Patients’ Anxiety and Hemodynamic Parameters During Coronary Angioplasty: A Randomized Controlled Trial
... a randomized controlled trial, conducted in the Catheterization Laboratory Unit of Baqiyatallah Hospital, in Tehran, ...64 patients, who were planned to undergo coronary angioplasty, was ... See full document
7
Targeted temperature management in traumatic brain injury
... TH versus fever control with tight hemodynamic monitoring and slow rewarming in patients with severe traumatic brain injury with a multicenter RCT (B-HYPO) in patients with severe TBI [33] ... See full document
10
Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions
... systemic hemodynamic objectives (in particular MAP target) are achieved, microcirculation abnormalities may persist ...ing hemodynamic objectives at the second phase of septic shock (when ... See full document
12
Targeted temperature management in the ICU: guidelines from a French expert panel
... analysed patients with initial non-shockable rhythm ...in patients with TTM: RR ...One randomized control trial [29] with a limited sample size (n = 30) compared patients treated ... See full document
14
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