[PDF] Top 20 Predictive potential of macrophage migration inhibitory factor (MIF) in patients with heart failure with preserved ejection fraction (HFpEF)

... With regard to diagnostic markers that might reflect changes in metabolic, inflammatory, and cardiovascular diseases, the cytokine macrophage migration inhibitory factor (MIF) plays an ... See full document

... of macrophage migration inhibitory factor (MIF) and vascular endothelial growth factor-C (VEGF-C) have been reported in a wide variety of ... See full document

... To assess tubulointerstitial and glomeru- lar staining, the number of labeled cells was counted in the randomly selected areas of the tissue under high power fields (40X) by means of a 0.02-mm 2 graticule fitted in the ... See full document

... Recent studies have identified MIF to be a pivotal regulator of the inflammatory and immune response (51, 53). While first described as a T cell–derived activ- ity, MIF has been shown to be a peptide released by ... See full document

... Characteristic of both chronic wounds and acute wounds that fail to heal are excessive leukocytosis and reduced matrix deposition. Estrogen is a major regulator of wound repair that can reverse age- related impaired ... See full document

... depression. Macrophage migration inhibitory factor (MIF) is an important multifunctional cytokine that is synthesized by several cell types in the ... See full document

... MIF: Macrophage migration inhibitory factor; MTB: Mycobacterium tuberculosis ; NLR: Neutrophil to lymphocyte ratio; NRI: Net reclassification improvement; OR: Odds ratio; PCT: Procalcitonin; ... See full document

... to macrophage and T cell accumulation, as well as progressive renal injury ...identified macrophage migration inhibitory factor (MIF) as an important regulator of cyst growth in ... See full document

... elevated in good correlation with tumor size, and the protein released from colon carcinoma cells stimulates the growth of NIH3T3 cells in a para- crine manner (25). Moreover, b-FGF cont[r] ... See full document

... The formation of DHI was attrib- uted to D-dopachrome tautomerase, the enzyme which catalyzes both tautomerization and decar- boxylation (13), and the factor responsible for producing DH[r] ... See full document

... Increased serum levels of macrophage migration inhibitory factor (MIF) in patients with microscopic polyangiitis.. Hirohito Kanemitsu Mizuho Matsunawa Kuninobu Wakabayashi Michihito Sa[r] ... See full document

... Otitis media with effusion (OME) is one of the most com- mon middle ear diseases and leads to an intractable hearing loss in both children and adults (12, 14). In children, many studies have demonstrated the involvement ... See full document

... MIF was originally discovered (in 1966) as a lymphokine, derived from activated T-cells, that in- hibited the random migration of macrophages in vitro and was shown to be involved in the mechanism of delayed-type ... See full document

... BMM compared to WT (Figure 4E). Exogenous rMIF directly impaired insulin-stimulated glucose transport in 3T3-L1-adipo- cytes (Figure 5A) which corroborates previous work [33]. Furthermore we demonstrated that ... See full document

... reperfusion injury of the heart during CPB (9,10). In adult patients experiencing acute myocardial infarction, serum MIF levels were shown to be significantly elevated within the first 30 h (11). Several studies of adult ... See full document

... (IL-1), IL-2, hematopoietic colony-stimulating factors (CSFs), platelet-derived growth factor (PDGF), and transforming growth factor (31 (TGF-j31) each can act as an autocrine growth fac[r] ... See full document

... The MIF mRNA level was significantly de- creased in adipose tissues in vivo, as described above, despite the fact that there was no signif- icant difference in plasma insulin level betwe[r] ... See full document

... MIF (Macrophage migration inhibitory factor) is a widely expressed 12.3 kDa cytokine with diverse physiological activities. It was first discovered in 1966 by Bloom and Bennett [1] as a ... See full document

... upregulated in the setting of inflammatory stimulation [15,16]. The findings in this study suggest that MIF is involved in the promotion of normal cell cycle and prolif- erative responses in murine dermal fibroblasts. ... See full document

... and macrophage migration inhibitory factor (MIF) play an important role in the pathobiology of septicemia and septic ...necrosis factor (TNF), lower bacterial circulating counts and ... See full document