[PDF] Top 20 Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles
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Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles
... (0.2 g) was dissolved in 20 mL of a 7:3 solution of methylene dichloride and absolute ethyl alcohol at 60 ° C. Lf (Tianchun Technology Co. Ltd, Nanjing, People’s Republic of China) (0.2, 0.6, 1.2, and 1.8 g) was ... See full document
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Preparation and in vitro/in vivo characterization of enteric-coated nanoparticles loaded with the antihypertensive peptide VLPVPR
... deoxyribonucleic acid recombinant technology, effectively decreased the blood pressure of spontaneous hypertensive rats; however, the effect only lasts 6 hours, likely due to its low absorption in the ... See full document
8
PREPARATION AND CHARACTERIZATION OF ISONIAZID CHITOSAN LOADED NANOPARTICLES
... chitosan nanoparticles in order to enhance its bioavailability and to reduce the dosing frequen ...isoniazid nanoparticles were prepared by Ionic gelation method with addition of suitable polymer (Chitosan) ... See full document
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Preparation, in vitro and in vivo evaluation of polymeric nanoparticles based on hyaluronic acid-poly(butyl cyanoacrylate) and D-alpha-tocopheryl polyethylene glycol 1000 succinate for tumor-targeted delivery of morin hydrate
... mixed nanoparticles showing higher cellular uptake compared with their counterparts without ...inhibition studies revealed that the nanoparticles were internalized mainly through clathrin- mediated ... See full document
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PREPARATION AND CHARACTERIZATION OF METFORMIN LOADED STEARIC ACID COUPLED F127 NANOPARTICLES
... In vitro release studies were accomplished for optimized batch MN3 and pure metformin by dialysis sac method [6]. Accurately weighed samples were placed in dialysis bags (12-14 kDa cut-off, HiMedia, India) ... See full document
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Fabrication, optimization, and characterization of umbelliferone β-D-galactopyranoside-loaded PLGA nanoparticles in treatment of hepatocellular carcinoma: in vitro and in vivo studies
... stearic acid as the stabilizing ...polymeric nanoparticles by successive washing. Nanoparticles were stabilized by dispersing them in a low volume of water and lyophilized for 24 ...blank ... See full document
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Preparation, characterization, and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4
... subsequent studies, 6-coumarin, as a fluorescent probe, was loaded into nanoparticles of the same particle size and zeta potential as those of the exendin-4-loaded nanoparticles to ... See full document
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Poly(lactic-<em>co</em>-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations
... Physicochemical characterization exhibited particle size of ...in vitro cell culture analysis using Hep-G2 cells and confocal microscopy studies revealed that BNP had the highest inhibition and ... See full document
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Self-assembled amphotericin B-loaded polyglutamic acid nanoparticles: preparation, characterization and in vitro potential against <em>Candida albicans</em>
... polyglutamic acid (PGA)-based formulation of amphotericin B (AmB) and evaluated its in vitro antifungal potential against Candida ...PGA nanoparticles were prepared in-house and had a mean size ... See full document
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Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin
... oleic acid ratio was an important factor with regard to both entrapment efficiency and particle ...in vitro drug release patterns showing relatively prolonged drug ...Pharmacokinetic studies ... See full document
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<p>Preparation of sustained release apremilast-loaded PLGA nanoparticles: in vitro characterization and in vivo pharmacokinetic study in rats</p>
... Twelve male Wistar albino rats weighing 180–220 g were used for the comparative pharmacokinetic studies of APM in rats. Animals were obtained from Animal Care Unit, College of Pharmacy, Prince Sattam Bin Abdulaziz ... See full document
9
Endostar-loaded PEG-PLGA nanoparticles: in vitro and in vivo evaluation
... romethane. The first emulsion (o/w) was formed between a dichloromethane solution of PEG-PLGA (1 mL) and endostar solution (0.05 mL) by shearing (2800 rpm for 60 seconds). Then a 2 mL aqueous solution containing 0.1% ... See full document
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Optimized formulation of multivesicular liposomes loaded with oleanolic acid enhanced anticancer effect in vitro
... per well. After reaching ~ 80% confluence, the cells were, respectively, treated for 24 h with 100 µ L of OA solution or OA-MVLs at different concentrations of 40, 80, 120, 160, 200, 240, 280, 300, 320 and 350 µ mol/L, ... See full document
14
Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil
... Several studies have revealed that nanostructured lipid carriers and self-microemulsifying drug delivery systems enhance the stability and water solubility of essential ... See full document
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DESIGN, CHARECTERIZATION AND IN-VITRO, IN-VIVO CORRELATION STUDIES FOR ELETRIPTAN LOADED TRANSDERMAL PATCHES
... is loaded with Eletriptan using Hydroxy Propyl methyl cellulose k-4 and k-15 individually as a release controlling polymers, Propylene glycol as permeation enhancer and Dibutylpthalate as a ...diffusion ... See full document
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Preparation and Characterization of Solid Lipid Nanoparticles Loaded with Cisplatin
... drug loaded nanocarriers and directly affects the therapeutic effect of ...Stearic acid increased acidic buffer pH ...of nanoparticles the larger the amount of drug released at the tumor ... See full document
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Preparation, characterization, in vitro and in vivo anti-tumor effect of thalidomide nanoparticles on lung cancer
... The nanoparticles with different drug loads were prepared by varying ratios of THA and MPEG-PCL (6, 8, and 10 ...The nanoparticles were spherical in shape, with a smooth sur- face, and were found to ... See full document
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Preparation, characterization, and in vivo study of rhein-loaded poly(lactic-<em>co</em>-glycolic acid) nanoparticles for oral delivery
... due to the wrapping of the polylactic acid skeleton, rhein can avoid rapid metabolism of CYP oxidase and lower the de gradation of PLGA, resulting in sustained-release effect. The improvement of the oral ... See full document
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PREPARATION AND PHYSICO-CHEMICAL CHARACTERIZATION OFCARVEDILOL- POLY (LACTIDE-CO-GLYCOLIC ACID) LOADED NANOPARTICLES.
... biodegradable nanoparticles are of particular interest as they provide protection of fragile molecules against enzymatic and hydrolytic degradation in the gastrointestinal tract 10 ...Thus, nanoparticles of ... See full document
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Preparation and In vitro / In vivo characterization of spray dried microsphere formulation encapsulating 4-chlorocurcumin
... found to be a pure compound containing only 0.3% starting material. The compound was also characterized by the peak purity assessment in HPLC. Subsequently, the formulations were prepared using the 4-chlorocurcumin ... See full document
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