[PDF] Top 20 Xenon for the prevention of postoperative delirium in cardiac surgery: study protocol for a randomized controlled clinical trial

... All statistical analyses will be performed using a com- mercially available software package (SAS software, ver- sion 9.2 of the SAS System for Windows, SAS Institute Inc., Cary, NC, USA). All tests will be 2-sided, and ... See full document

... documented delirium prior to ICU admission; reasons that impair delirium assessment with the CAM-ICU (serious auditory or visual disorders, unable to understand Dutch or English; severely mentally disabled; ... See full document

... of clinical factors and non-uniform reporting of clinical parameters such as stoma site, patient characteristics, and type of surgery all contributed to the ... See full document

... subjects randomized to physiologic oxygen- ation or hyper-oxygenation to have similar vital signs, similar responses to surgery, similar response to medica- tions, and to not warrant any differences in care ... See full document

... A study by Costa et ...their postoperative process was associated with unex- pected pain and fatigue ...after surgery because education and support maintain or increase the patient’s feelings of ... See full document

... undergoing cardiac surgery need general anesthesia from either intravenous (IV) anesthetics (such as propofol) or volatile anesthetics (such as isoflurane, sevoflurane, and ...improved postoperative ... See full document

... require surgery [2]. Pa- tients who undergo cardiac surgery can have significant pain, sleep impairment [3, 4], postoperative delirium (POD), and cognitive decline (POCD) [5], which can ... See full document

... severe cardiac failure or patient with severe impaired left ventricular systolic function; patient with known severe lung and/or airway disease, or severe chronic respiratory insufficiency, or a sustained homecare ... See full document

... The MMSE score is an assessment tool used in nearly all medical fields. The MMSE is a 30-item checklist of symptoms suggestive of cognitive decline. Patients lose 1 point for each symptom that manifests during the ... See full document

... and postoperative characteristics are shown in Table ...poorer clinical outcome, including length of stay in the ICU and hospital (Table ...the protocol and were individual medical ...first ... See full document

... interventional study on critically ill adults (VITdAL-ICU) suggests that rapid re- pletion of vitamin D may improve outcomes ...This trial randomized 475 critically ill adults to an initial enteral ... See full document

... following cardiac surgery with an incidence of 30–40% [1, ...control cardiac rate and/or rhythm, anticoagu- lation, and/or electrical cardioversion; each of which have side effects that cannot be ... See full document

... of delirium is the disruption of the sleep-wake cycle and circadian rhythm ...post surgery [23] and after the administration of certain opioids [24], possibly contributing to the disrupted sleep-wake cycle ... See full document

... DSI. Delirium assessment will be per- formed once every day starting from postoperative day ...the protocol permits a window period of 14 days before and after the 1-month follow-up and of 3 months ... See full document

... inattention, delirium is associated with an increased incidence of postoperative complications, prolonged hospital length of stay, and greater in-hospital mortality ...of postoperative ... See full document

... each clinical site using a blocked randomi- zation ...be randomized the day before surgery, once the patient has provided written informed consent and satisfied all the study eligibility cri- ... See full document

... the delirium management ...on delirium and its management while the caregiver mostly refers to personal knowledge of the pa- tient as well as previous experience with ...of delirium and of the ... See full document

... after surgery shivering with grade 0, 1, 2, and 3 in the Normal Saline group was seen in 27, 7, 5, and 5 cases, respectively, in the Pethidine group shivering with grade 0, 1, 2, and 3 was seen in 43, 1, 1, and 0 ... See full document

... current study is to test the effectiveness of 30 hours of computer-based SocialVille training to improve social cognition and functional outcome in schizophrenia, compared with an active control ... See full document

... After screening and signing of informed consent and end-of-study measurements, the SF-36, physical fitness, and social cognitive theory will be carefully recorded. Monitoring will be performed by personnel ... See full document