[PDF] Top 20 <p>Pre-mRNA Processing Factor 8 Accelerates the Progression of Hepatocellular Carcinoma by Regulating the PI3K/Akt Pathway</p>
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<p>Pre-mRNA Processing Factor 8 Accelerates the Progression of Hepatocellular Carcinoma by Regulating the PI3K/Akt Pathway</p>
... 100. 8 The formation of the E-complex involves the initial recognition of an intron by the ...mature mRNA for the nuclear export, releasing the lariat intron, which will be degraded, and the snRNPs, which ... See full document
14
miR-450b-5p loss mediated KIF26B activation promoted hepatocellular carcinoma progression by activating PI3K/AKT pathway
... risk factor for prognosis of HCC ...affecting progression of HCC via inhibiting acti- vation of PI3K/AKT ...KIF26B regulating activation of PI3K/AKT ... See full document
12
<p>LncRNA HEIH Confers Cell Sorafenib Resistance in Hepatocellular Carcinoma by Regulating miR-98-5p/PI3K/AKT Pathway</p>
... that PI3K/ AKT pathway is an important underlying mechanism of acquired resistance to ...activate PI3K/AKT path- way, and inactivating the PI3K/AKT pathway ... See full document
11
microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma
... In our previous study, we found that miR-26a expression was lower in HCC tumor samples than in paired noncan- cerous liver tissue, and patients with lower miR-26a expression had shorter overall survival compared with ... See full document
11
<p>lncRNA PCBP1-AS1 Aggravates the Progression of Hepatocellular Carcinoma via Regulating PCBP1/PRL-3/AKT Pathway</p>
... PCBP1 mRNA and protein expression in our experimental ...the mRNA levels of PCBP1 were signi fi cantly decreased when the PCBP1-AS1 was over- expressed in MHCC97H and Huh7 cells (Figure 5A), while its ... See full document
14
<p>Pseudogene DUXAP10 acts as a diagnostic and prognostic marker and promotes cell proliferation by activating PI3K/AKT pathway in hepatocellular carcinoma</p>
... Pseudogenes, as non-coding protein genes, have been long considered to be non-functional transcriptional relics of the genome. To date, only a few pseudogenes have been demonstrated to be HCC oncogenes, and the roles of ... See full document
12
MYO18B promotes hepatocellular carcinoma progression by activating PI3K/AKT/mTOR signaling pathway
... lung carcinoma and 47% of small cell lung carcinoma cell lines, and res- toration of MYO18B expression can effectively suppress the growth of lung cancer ...by regulating cell movement and ... See full document
9
Interleukin-8 promotes integrin β3 upregulation and cell invasion through PI3K/Akt pathway in hepatocellular carcinoma
... Invasion and metastasis of cancer cells is a complex, dy- namic and multistage process, involving a series of changes in the interaction between invasive cells and extracellular matrix or neighboring cells. Integrins ... See full document
10
<p>SPOCD1 accelerates ovarian cancer progression and inhibits cell apoptosis via the PI3K/AKT pathway</p>
... transcription factor S-II (TFIIS) family. 8 SPOCD1 was initially found to interact with testis protein phosphatase 1 which is a major eukaryotic serine/threonine-speci fi c phosphatase regulating ... See full document
9
<p>RAB43 Promotes Gastric Cancer Cell Proliferation and Metastasis via Regulating the PI3K/AKT Signaling Pathway</p>
... the progression of GC. 15 PI3K/AKT is a common signaling pathway downregulated in human ...16 PI3K/AKT has extre- mely important biological functions in cell growth, prolif- ... See full document
10
<p>microRNA-944 inhibits the malignancy of hepatocellular carcinoma by directly targeting IGF-1R and deactivating the PI3K/Akt signaling pathway</p>
... miR-944 plays tumor-suppressive or tumor-promoting activities during carcinogenesis and cancer progression. For example, miR-944 upregulation inhibits the metastasis of colorectal cancer cells by regulating ... See full document
13
EGR1 mediates miR-203a suppress the hepatocellular carcinoma cells progression by targeting HOXD3 through EGFR signaling pathway
... and PI3K/AKT pathways [39, ...the progression of cells [42]. Here, we observed that the expression of p-AKT, p-ERK1/2, CDK1, and CCNB1 was downregulated by miR-203a expression, ... See full document
15
<p>Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway</p>
... breast carcinoma and protects cancer, and the expression of DERL1 was associated with the grade and axillary lymph node metas- tasis of human breast carcinoma ...via PI3K/AKT/and ERK ... See full document
11
<p>Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway</p>
... signaling pathway as well as inhibits vascular endothelial growth factor (VEGF), platelet-derived growth factor, and KIT ...disease. 8–11 However, HCC ’ s long-term response to treatment is ... See full document
13
<p>Knockdown of lncRNA TDRG1 Inhibits Tumorigenesis in Endometrial Carcinoma Through the PI3K/AKT/mTOR Pathway</p>
... 3, p-mTOR, mTOR, p-AKT, AKT, p-PI3K, PI3K, β -actin, and HRP-conjugated secondary antibody were obtained from Abcam (Cambridge, MA, ... See full document
10
Tanshinol inhibits the growth, migration and invasion of hepatocellular carcinoma cells via regulating the PI3K-AKT signaling pathway
... Briefly, formalin-fixed paraffin-embedded tumor tissues were prepared in 4- µ m sections. After performing dewax- ing, rehydration, blocking endogenous peroxidase activity, and antigen retrieval steps, sections were ... See full document
13
<p>Expression of Carboxypeptidase X M14 Family Member 2 Accelerates the Progression of Hepatocellular Carcinoma via Regulation of the gp130/JAK2/Stat1 Pathway</p>
... malignant biological properties. To date, some CPs have been recognized as potential therapeutic and diagnostic bio- markers. For instance, a recent study revealed that carbox- ypeptidase A4 (CPA4) predicted a poor ... See full document
12
The PI3K-AKT-mTOR pathway activates recovery from general anesthesia
... that PI3K-AKT-mTOR pathway proteins in normal rats were expressed at low levels, while there was increased expression of p-AKT, p-mTOR and p-P70S6K in brain tissues of ... See full document
14
<p>MicroRNA-145 inhibits growth of laryngeal squamous cell carcinoma by targeting the PI3K/Akt signaling pathway</p>
... the PI3K/Akt signaling pathway to promote devel- opment and progression of laryngeal cancer, 19–21 , but no studies have evaluated the correlation between the PI3K/ Akt signaling ... See full document
12
<p>MicroRNA-503 Inhibits Non-Small Cell Lung Cancer Progression By Targeting PDK1/PI3K/AKT Pathway</p>
... Quantitative real-time PCR (qRT-PCR) was performed to evaluate miR-503 expression in NSCLC tissues. MiR-503 expression in NSCLC tissues was markedly lower than that in the adjacent normal tissues (P<0.05, N=42 ... See full document
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