[PDF] Top 20 Productive Replication and Evolution of HIV-1 in Ferret Cells
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Productive Replication and Evolution of HIV-1 in Ferret Cells
... for HIV-1 has not been forthcoming, with the principal obstacles being species-specific restriction mechanisms and deficits in HIV-1 dependency ...nonreceptor HIV-1 dependency ... See full document
11
Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus
... T cells in ES1, ES8, and ES9, proving that some of the virus in this compartment is replication competent (4, ...of evolution of proviral sequence to excessive G-to-A hypermutation ...However, ... See full document
11
Restriction of HIV-1 replication by unique TRIM22 isoforms.
... type 1 (HIV-1) is a retrovirus that primarily infects CD4+ T lymphocytes (T cells), leading to gradual destruction of the immune system and the eventual progression to Acquired Immune ... See full document
101
Endothelial Cell Stimulation Overcomes Restriction and Promotes Productive and Latent HIV-1 Infection of Resting CD4+ T Cells
... T cells permissive for HIV replication (30, ...T cells, CD3/CD28-activated T cells, EC ⫹ and EC ⫺ , and MCF7, a human breast cancer cell line that when cocultured with resting T ... See full document
12
Inhibition of highly productive HIV-1 infection in T cells, primary human macrophages, microglia, and astrocytes by Sargassum fusiforme
... T cells, we tested for inhibition of VSV/NL4-3 in CD4-negative primary ...negative cells that are nonproductively infected by HIV-1 in vivo [16], and in vitro ...these cells fully ... See full document
12
Unstimulated Primary CD4+ T Cells from HIV-1-Positive Elite Suppressors Are Fully Susceptible to HIV-1 Entry and Productive Infection
... of HIV-1-infected individuals who maintain viral loads below the limit of detection of commercial assays for many ...T cells to ...T cells from ES can be infected by HIV-1 ... See full document
8
Productive infection of dendritic cells by HIV 1 and their ability to capture virus are mediated through separate pathways
... with HIV or that capture vi- rus en route to lymph nodes) may activate and infect TC con- comitantly, and thus contribute to Ag-specific depletion of ...viral replication have been documented after ... See full document
12
HIV-1 Replication in Langerhans and Interstitial Dendritic Cells Is Inhibited by Neutralizing and Fc-Mediated Inhibitory Antibodies
... limiting HIV replication in these cells ...in HIV-1 infection was assessed in our model by competition experiments using three antibod- ies directed against human langerin CD207 (one ... See full document
9
Analysis of CA Content and CPSF6 Dependence of Early HIV 1 Replication Complexes in SupT1 R5 Cells
... on HIV-1 cell entry or viral replication, we compared HIV-1 membrane fusion and infectivity in the presence or absence of the ...established HIV-1 entry assay detecting ... See full document
20
Stimulation of HIV-1 Replication in Immature Dendritic Cells in Contact with Primary CD4 T or B Lymphocytes
... inhibit HIV-1 trans-infection. The greater efficiency of HIV-1 production in immature MoDCs cocul- tured with primary lymphocytes highlights the need to recon- sider the potential inhibitory ... See full document
11
Productive Replication of vif-Chimeric HIV-1 in Feline Cells
... CrFK.X4.CD4.Vif-GFP cells) demonstrates that ex- pression of an active Vif alone alleviates the restrictions to HIV-1 replication in this cell ...T cells to an A3- characteristic ... See full document
18
Highly Productive Infection with Pseudotyped Human Immunodeficiency Virus Type 1 (HIV-1) Indicates No Intracellular Restrictions to HIV-1 Replication in Primary Human Astrocytes
... the HIV-1 structural and regulatory proteins expressed in astrocytes, cells were infected with pseudotyped NL4-3 or NL-P1, harvested at the peak of infec- tion (7 days) and during the decline of ... See full document
9
Consistent Inhibition of HIV-1 Replication in CD4+ T Cells by Acyclovir without Detection of Human Herpesviruses
... T cells. As shown in Table 1, all adult blood donors had detectable levels of the T-cell-tropic HHV-6 and -7, with HHV-7 being present in ⬍ ...inhibited HIV-1 replication in the ... See full document
5
Inactivation of the Human Cytomegalovirus US20 Gene Hampers Productive Viral Replication in Endothelial Cells
... virus replication at different days ...p.i., cells were fixed, permeabilized, and immunostained with anti-IEA, UL44, or UL99 MAbs, ...positive cells to show virus addition, since random fields were ... See full document
15
Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication
... ␣ 1, Imp ␣ 3, Imp ␣ 5, and Imp ␣ 7, in HIV-1 replication by specific knockdown of each isoform in human ...␣ 1, Imp ␣ 3, Imp ␣ 5, and Imp ␣ 7, we were able to efficiently knock down ... See full document
14
Strong Ability of Nef-Specific CD4+ Cytotoxic T Cells To Suppress Human Immunodeficiency Virus Type 1 (HIV-1) Replication in HIV-1-Infected CD4+ T Cells and Macrophages
... those cells infected with Vac-WT did not induce any IFN- ␥ production ...T cells from the Nef-specific clones to produce IFN- ␥ , whereas those cells pulsed with NL-Xh (Nef-depleted) virus particles ... See full document
10
Inhibition of HIV 1 replication by cyclopentenone prostaglandins in acutely infected human cells Evidence for a transcriptional block
... Immunoblot analysis. Uninfected and HIV-1 infected CEM-SS cells were washed twice with PBS and lysed in lysis buffer containing 50 mM Tris (pH 7.2), 150 mM NaCl, 0.1% SDS, 2 mM PMSF. An equal amount ... See full document
10
The MHC II transactivator CIITA inhibits Tat function and HIV 1 replication in human myeloid cells
... the HIV-1 promoter by Tat, several deletion mutants of CIITA were expressed in 293T cells and analyzed for their ability to suppress Tat- promoted HIV-1 LTR-dependent luciferase ... See full document
12
Dual role of autophagy in HIV-1 replication and pathogenesis
... enabling HIV-1 to subvert autophagy in macrophages have been elucidated ...that HIV-1 Gag and Nef interact with the autophagy proteins LC3 and Beclin 1 ...of HIV-1 ... See full document
13
The dual role of tetraspanin CD63 in HIV 1 replication
... stage HIV-1 replication, CD63 siRNA was transfected into U1/HIV-1 cells, which are chronically infected monocytoid cells harboring 2 integrated copies of provirus per cell ... See full document
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