[PDF] Top 20 Prognostic role of long noncoding RNA NEAT1 in various carcinomas: a meta-analysis

... between NEAT1 expression and LNM (pooled OR: ...subgroup analysis to precisely assess the prognostic effect of NEAT1 on OS and LNM, ...high NEAT1 expres- sion exhibited a significant ... See full document

... However, our conclusions should be considered with cau- tion for the following five reasons. First, there are only nine eligible articles included in our analyses, leading to the rela- tive insufficiency of studies in ... See full document

... regulatory role of HOXA11-AS in tumorigenesis and tumor progres- sion have been extensively investigated in various types of ...endogenous RNA and regulates ROCK1 expression by sponging miR-124-3p, ... See full document

... phosphorylated RNA poly- merase II in nuclear speckle compartment, the interac- tion of unmethylated Pc2 with theTUG1, overlapping the histone H3K36me2 peaks and the recruitment of Sp1 on LTBP3 ...of ... See full document

... There were still many limitations in this meta- analysis. Firstly, the roles and biological functions of lncRNA-H19 differed in different types of cancer. The heterogeneity may be increased, thus ... See full document

... important role in the differentia- tion, proliferation, and genome maintenance of cells, but also with the development and progression of cancer ...the prognostic impact of lncRNA XIST remains enigmatic, ... See full document

... in various cancers. We performed this meta-analysis to clarify its promising functions as a prognosis marker in malignant ...this meta-analysis that included 1,081 cancer ...Subgroup ... See full document

... Recently, role of lncRNAs in human diseases has grown in importance due to advancement in the application of next-generation genome wide sequencing and microar- ray ...important role in cancer prognosis ... See full document

... the role of HOXD-AS1 in digestive tumors, which needs additional published articles to explore this ...this meta-analysis are limited, so more studies with larger sample sizes and various ... See full document

... important role for lncRNAs in carcinogenesis and cancer ...novel prognostic biomarkers for ...tein-coding RNA (DANCR) is located on chromosome 4, with the closest adjacent annotated genes being USP46 ... See full document

... To validate the abovementioned results, we first evaluated the expression of HNF1A-AS1 in five kinds of cancers using the data from TCGA. As shown in Figure 6A, HNF1A-AS1 was overexpressed in four of them, including ... See full document

... clinical prognostic biomarker as well as new therapeutic target for ...with various cancer subtypes, and developing novel lncRNA-based strategies for diagnosis and targeted therapies appear very promising, ... See full document

... unveiled. Various viruses, such as influenza virus (IAV), coronavirus, enterovirus, human immu- nodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), Japanese encephalitis virus (JEV), and ... See full document

... sensitivity analysis as well as meta-regression showed no factors profoundly influencing ...subgroup analysis, sources of miR-126 (tissue or blood), miR-126 assay method (ISH or qRT-PCR), and data ... See full document

... Taken together, the present study is the first meta-analysis to assess the expression of lncRNAs and their clinical value in patients with bladder cancer. As a result, several specific lncRNAs were ... See full document

... provirus. Long noncoding RNAs (lncRNAs, ⬎ 200 nucleotides) are increasingly recognized to play important roles in ...pression analysis of lncRNAs in HIV-1-infected primary monocyte-derived macro- ... See full document

... for NEAT1 involvement in AD development, we explored miRNA that bind to NEAT1 by bioinformatics ...and NEAT1, suggesting that miR-107 might be targeted by NEAT1 ...the NEAT1- WT group, ... See full document

... were subcutaneously injected into the nude mice. One week later, intratumor injection of PBs, mir-nc, or mir-124 mimics were performed once a week for 6 consecutive weeks according to indicated groups (n=6 in each ... See full document

... a prognostic seven- lncRNA panel and demonstrated it as a powerful prognostic predictor for ovarian ...regression analysis revealed that the seven- lncRNA signature was independent of the main ... See full document

... Sensitivity analysis indicated that the pooled HRs were not significantly influenced by omitting any single study (Figure 3). The shape of the funnel plot did not reveal any evidence of obvious asymmetry (Figure ... See full document