[PDF] Top 20 Prognostic significance of CD44V6 expression in osteosarcoma: a meta-analysis

... present meta-analysis, indicating a sta- tistically significant role of CD44V6 on overall survival (HR = ...the expression of CD44V6 from biopsy tissue. Our meta-analysis ... See full document

... between CD44v6-positive hepatocellular carci- noma (HCC) and clinicopathological features and its effect on ...A meta-analysis based on published stud- ies was conducted to accurately evaluate the ... See full document

... that CD44V6 may act as an onco-protein in the metasta- sized OS ...that CD44V6 is conspicuous and homogeneous expression within malignant tumors, antibodies recognizing CD44V6 were used in ... See full document

... extracted prognostic or clinico- pathological ...and prognostic outcomes (breast cancer-specific sur- vival [BCSS], overall survival [OS], distant metastasis-free survival [DMFS], recurrence-free survival ... See full document

... present meta-analysis showed that in- creased expression of HIF-1α protein, as detected with IHC, was significantly associated with larger tumor size (T3/T4), more advanced TNM stage (III/IV), and ... See full document

... Gal-1 expression group versus the low Gal-1 expression group for OS, CSS, DFS, and RFS, if ...multivariate analysis were reported in a study, only the latter was chosen since its accuracy increased ... See full document

... Sensitivity analysis was performed to examine the effects of individual study on the overall ...sensitivity analysis showed that HRs and their 95% CIs did not change significantly after the exclusion of any ... See full document

... survivin expression was related to poor clinical ...a prognostic biomarker, our results are of great value in view of the emergence of new drugs targeting ... See full document

... PD-L1 expression maintains the homeostasis of the immune ...The prognostic value of PD-L1 in various have been investigated, such as breast cancer [7], non-small cell lung cancer [8], pan- creatic cancer ... See full document

... Two investigators extracted related data respectively and came to an agreement on the following items. Original data of elementary demographic characteristics (year of publication; authors of article; region; the ... See full document

... According to our study, higher level of miR-126 predicted better OS (HR 0.70, 95% CI: 0.62–0.79, random-effects model), especially in digestive system cancers (HR 0.70, 95% CI: 0.59–0.83, fixed-effects model) and ... See full document

... form, CD44v6, which contains sequences encoded by exon 6, has been proposed as a potential prognostic marker in many epithelial and none- pithelial malignancies in both early and metastatic phases of ... See full document

... high expression of HIF-1 α in patients with osteosarcoma predicts low survival rate and poor clinicopathological ...valuable prognostic factor for osteosarcoma patients and predict high cancer ... See full document

... with osteosarcoma of the extremity can be cured with a relatively nonaggressive regimen of chemotherapy ...localized osteosarcoma experience recurrent or progressive disease [15,16] and the average survival ... See full document

... All included articles were pub- lished between 1997-2014. Nine studies were distributed in China. The remaining 3 stud- ies were from Japan. All eligi- ble studies were retrospective. Tumor histology of the 9 studies was ... See full document

... this analysis had to meet the follow- ing inclusion criteria: (1) patients were pathologically diagnosed with any type of human ...CXCL5 expression levels were determined in human tissues or plasma ...the ... See full document

... PD-L1 expression and prognosis of colorectal cancer and then concluded that there was no connection between ...a prognostic indi- cator of colorectal cancer, but they misapplied risk ratio (RR), a specific ... See full document

... the analysis of plasma samples, all the four studies have a significant association between K-ras mutations and poorer OS, and a higher combined HR of ...the prognostic value of mutant ...great ... See full document

... and prognostic value of cyclooxygenase-2 (COX-2) expression in patients with head and neck cancer (HNC), but their results remain ...a meta-analysis was carried ...final analysis. Our ... See full document

... present meta-analysis need to be pointed ...the significance of Cdx2 expres- sion as a predictor of of outcome in gastric ...in prognostic factors meta-analyses, variability in ... See full document