[PDF] Top 20 Pulmonary fibrosis: patterns and perpetrators

... lung fibrosis and in IPF through epithelial-to-mesenchymal transition ...kidney fibrosis, although it remains an area of controversy (41, ...experimental pulmonary fibrosis in vivo, two groups ... See full document

... A three-round Delphi panel of clinical experts was held between December 2012 and June 2013 using postal ques- tionnaires to describe the treatment patterns and resource use associated with IPF. The first ... See full document

... with fibrosis in SSc and IPF could address the unmet need for reliable and accurate biomarkers of ...expression patterns in fibrotic ...are patterns of miRNAs that closely associate with pathological ... See full document

... IPF is a progressive, permanent disease of the lung that has no ending choice for treatment other than transplantation. It is characterized by replacement of the normal lung tissue by fibrotic scarring, honeycombing, and ... See full document

... FILD patterns at HRCT, but are also closely associated to the extent of different interstitial abnormalities in the lung ...of pulmonary fibrosis such as ground glass change and reticulation generate ... See full document

... lung fibrosis, only 23 cases with definite histologic and clinical criteria of UIP were ...restrictive patterns on pulmonary function test (PFT) and the imaging findings were consistent with the ... See full document

... 34% over the study period. Although mortality rates were higher for men compared to women, they increased more rapidly in women, potentially due to changes in smoking patterns. Mortality rates were higher in older ... See full document

... In AE of IPF patients, Akira proposed radiological staging. They reviewed 64 episodes of 58 patients with IPF. A semi- quantitative analysis of overall extent of parenchymal abnormalities, extent of alveolar opacity ... See full document

... The clinical diagnosis of asbestosis was based on exposure status, clinical findings, and radiologic evidence of interstitial lung disease. A radiographic diagnosis of asbestosis was established in 62 (34%) of 183 cases ... See full document

... their pulmonary function into mild (n ⫽ 5), moderate (n ⫽ 9), and severe (n ⫽ 1) disease, were recruited at the CF unit of the Ramón y Cajal University Hospital (Madrid, ...the pulmonary microbiome might ... See full document

... TGF- β 1 mediates many fibrogenic responses, including myofibroblast activation and differentiation [23]. TGF-β1 also regulates the epithelial–mesenchymal transition, a phenotypic change in which epithelial cells acquire ... See full document

... cystic fibrosis, asthma, lung cancer, COPD (chronic obstructive pulmonary disease) and IPF is well- documented ...of pulmonary fibrosis ... See full document

... CPFE is a distinct but under-recognised and common syndrome with a characteristic presentation. It is more frequent (30%) than previously believed and may have a worse prognosis than IPF alone, with PH being the major ... See full document

... Obstructive sleep apnoea (OSA) is common in IPF [39]. OSA itself, with intermittent hypoxaemia, may promote profibrotic mechanisms [49]. In the general population, chronic cough is more prevalent in OSA and can be ... See full document

... inpatient pulmonary rehabili- tation can result in bene fi cial outcome measures in patients with ...3-week pulmonary rehabilitation programme in an inpatient setting in consideration of the Japanese Table 5 ... See full document

... former had higher esophageal acid exposure, greater num- ber of both acid and non-acidic re fl ux episodes and major number of proximal re fl uxes than the latter group (p<0.01). Moreover, the number of re fl ux episodes ... See full document

... TRAIL is now known to have crucial functions in regulation of inflammation and immune response. These systems are significant in the pathogenesis of many forms of lung disease, including autoimmune disorders and ... See full document

... for pulmonary function tests obtained on a patient at any particular point with normative values derived from population ...abnormality. Pulmonary function tests (PFTs) is a generic term used to indicate a ... See full document

... emitted dose and fine particle fraction were independent from the pressure applied and showed dose repeatability. However, with Twister the aerosolization was pressure-dependent indicating poor compatibility between the ... See full document

... Background: Over the last years, increasing attention has been focused on the prevalence of ob- structive sleep apnea (OSA) in idiopathic pulmonary fibrosis (IPF). Objective: To determine the prevalence of ... See full document