[PDF] Top 20 Recipient cell nuclear factors are required for reprogramming by nuclear transfer
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Recipient cell nuclear factors are required for reprogramming by nuclear transfer
... The cell-cycle dependence of Brg1 localization we observed was consistent with that previously reported in somatic cells and in mouse oocytes, in which Brg1 localizes to the interphase nucleus, but is dispersed in ... See full document
11
HIRA dependent H3.3 deposition is required for transcriptional reprogramming following nuclear transfer to Xenopus oocytes
... transcriptional reprogramming. We have first asked whether HIRA, known to be required for ...also required for ...be required for the maintenance of ongoing transcription in the ESCs ...for ... See full document
10
Nuclear reprogramming in zygotes
... ES cell nuclei, resulting in pseudo-pronuclei forma- tion (Gao et ...be required for male pronucleus formation upon fertilization of both mouse and porcine oocytes (Balakier and Tarkowski, 1980; Ogushi et ... See full document
10
Critical Developmental Stages for the Efficiency of Somatic Cell Nuclear Transfer in Zebrafish
... the reprogramming processes after nuclear ...that reprogramming can be divided into two major events that occur just after SCNT: 1) the reversal to pluripotency and 2) the establishment of new ... See full document
11
Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer
... pronounced effect at reducing proliferation. This is consistent with previous reports showing that the Activin A/Nodal pathway is required to maintain self-renewal of mouse epiblast stem cells (Brons et al., 2007; ... See full document
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The cytoplasm of mouse germinal vesicle stage oocytes can enhance somatic cell nuclear reprogramming
... after nuclear transfer ...somatic cell genomes became phosphorylated and the chromosomes underwent condensation without the presence of the GV ...essential factors are present in the nucleus ... See full document
11
Somatic cell nuclear transfer: failures, successes and the challenges ahead
... As cell division begins, the total number of mitochondria within each blastomere decreases due to dilution with no new mitochondrial biosynthesis (John et ...the nuclear-encoded replication factors ... See full document
9
Discovery of porcine maternal factors related to nuclear reprogramming and early embryo development by proteomic analysis
... crucial factors affecting embryo development ...the nuclear reprogramming of sperm and somatic cell undergoes two distinct ...the nuclear morphology of donor cell, to reverse the ... See full document
10
Fam60al as a novel factor involved in reprogramming of somatic cell nuclear transfer in zebrafish (Danio rerio)
... Nuclear reprogramming involves the process of reactivating specific genes in embryonic cells and silencing specific genes in somatic ...the reprogramming process, but are unable to acquire the traits ... See full document
9
Faithful reprogramming to pluripotency in mammals what does nuclear transfer teach us?
... ABSTRACT Nuclear reprogramming toward pluripotency has been now achieved either in vivo by somatic cell nuclear transfer into the ooplasm of an enucleated egg, or in vitro by three ... See full document
14
Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCs
... somatic cell reprogramming to pluripotency [15, ...transcription factors and three Polycomb proteins associated with rDNA in mouse ESCs, such as SOX2, NANOG, KLF4, STAT3, SMAD1, and C- MYC, suggested ... See full document
10
Induced pluripotent stem cells (iPSCs) based approaches for hematopoietic cancer therapy
... the reprogramming and reducing the potentially harmful side effects of the reprogramming process ...transcription factors in the earliest studies can be potentially mutagens, researchers are not ... See full document
14
Epigenetic modifications of embryonic stem cells: current trends and relevance in developing regenerative medicine
... Many factors infl uencing SCNT effi ciency include; donor cell phenotype (Table 2), developmental stage of recipient oocytes during nuclear transfer (Hall et al 2007), cell cycle ... See full document
12
Interspecies somatic cell nuclear transfer is dependent on compatible mitochondrial DNA and reprogramming factors
... better cell organisation (Figure 4Ci), more similar to the control parthenotes (Figure 4Ciii) than following supplementation with somatic cell extract (Figure ...donor cell, we generated 207 ... See full document
13
Application of new biotechnologies for improvements in swine nutrition and pork production
... inappropriate reprogramming of the donor nuclear DNA to metabolically normal pheno- types; and (b) inappropriate interaction between the embryo/fetus and the uterus of the recipient ...complex ... See full document
16
Insertion of a Classical Nuclear Import Signal into the Matrix Domain of the Rous Sarcoma Virus Gag Protein Interferes with Virus Replication
... (32). Nuclear import is mediated by a nuclear localization signal (NLS) within the N-terminal matrix (MA) ...CRM1-dependent nuclear export signal (NES) within the p10 domain of Gag mediates ... See full document
9
The adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoter.
... Sequences in ElA proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.. Inductio[r] ... See full document
9
The Influence of Genetic Background on Stem Cell Derivation and Variability.
... Lentiviral reprogramming on the other hand has higher efficiency due to the fact that lentiviruses, a subtype of retrovirus, can infect both non-dividing and actively dividing cell ...types. ... See full document
300
Walther, Tobias (2002): The role of Peripheral Nuclear Pore Complex (NPC) structures in nuclear transport and NPC architecture. Dissertation, LMU München: Fakultät für Biologie
... the nuclear envelope differs from the ER only by the presence of the ...inner nuclear membrane, however, is distinguished by the presence of unique transmembrane proteins (Holmer and Worman, ...the ... See full document
150
Transfer reactions for nuclear astrophysics
... To bypass these difficulties (sub–threshold resonances, radioactive nuclei,...) indirect methods such as transfer reactions [1], Coulomb dissociation [2], ANC method [3] and Trojan Horse Method [4] are good ... See full document
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