[PDF] Top 20 On reporting results from randomized controlled trials with recurrent events

... previous events, and the marginal event-number-specific rate ratios, which summarize the intervention effect on the transition rate of experiencing a certain number of events from study ...of ... See full document

... Multiple-treatment arms are possible sources of multi- plicity in an RCT [6,10]. This multiplicity is related to the possibility of performing several pairwise tests to de- termine the most effective arm. In such a ... See full document

... of results, particularly if the component endpoints are of widely differing importance to patients and the magni- tude of effect differs markedly across components ...these results put into practice in ... See full document

... the reporting quality of 14 PT trials and 1 OT trial on children with ...Seven trials demonstrated a sufficient description of at least half of the evaluated items, whereas 2 trials gave ... See full document

... of reporting of 70 RCTs on EA for stroke was generally ...ranged from 16 to ...The reporting of de- tail items in STRICTA of acupuncture rationale is 1a (91%), 1b (86%) and 1c 0%; of needling details ... See full document

... deviations from the predetermined number of participants, measures (intention-to-treat, ITT) 32 can be taken to lower the occur- rence of related ...readers, results of subgroup analyses should not be ... See full document

... causality, reporting criteria, analysis methods and presentation of AE data. results We identified 184 eligible reports (BMJ n=3; JAMA n=38, Lancet n=62 and NEJM ...withdrew from the trial were well ... See full document

... adverse events expected with different treatment ...clinical trials research, including Phase I. Currently, Phase I trials in rectal cancer focus mainly on the maximum tolerated dose relating to the ... See full document

... Selective reporting of analyses of outcomes may also affect the validity of clinical trial ...the results of this analysis being more favorable than those of the inten- tion-to-treat analysis (which more ... See full document

... information from the authors or their ...the trials may not be published and thus not ...The reporting of methodological aspects of RCTs does not necessarily reflect the conduct of the trial ...our ... See full document

... For more than 3000 years, practitioners in China have used acupuncture to treat various diseases, including the sequelae of stroke. Acupuncture is widely used to improve motor, sensation, speech and other neurological ... See full document

... dementia. Randomized controlled trials (RCTs), published in English, comparing cognitive rehabilitation or cognitive training interventions with control conditions and reporting relevant ... See full document

... Our results show that, despite the FDAAA require- ment to post results from scientifically appropriate tests of statistical significance, only half of the trials with results posted ... See full document

... compared to standard therapies. The author needs to show how the sample size was determined, as it not always easy to recruit enough participants within a set time besides those that withdraw. Approximately 66% failed to ... See full document

... ’ reporting was poor, especially in the categories of ‘ randomization ’ , ‘ allocation concealment and implementation ’ , ‘ blinding ’ and ‘ ITT analysis ’ with a positive rate of less than ... See full document

... adverse events of sustained hormone deprivation, plus the costs of this therapy, motivated the intermittent treatment ...all randomized controlled trials that compared the efficacy and adverse ... See full document

... publications reporting the results of randomized controlled trials involving human participants with two years of available data before and after ...retraction, from Web of ... See full document

... We will use the Cochrane Risk of Bias Tool to appraise RCTs [11] and the Cochrane Effective Practice and Organization of Care Risk of Bias Tool for controlled clin- ical trials, interrupted time series, and ... See full document

... Two review authors (JT and EM) independently screened all titles and abstracts identified from searches to determine which met the inclusion criteria. We retrieved potentially relevant papers in full text. The ... See full document

... We are fully aware of several limitations in this study. The RCTs with relatively small number of women included in this meta-analysis may not have been sufficient to recognize small differences between groups. There ... See full document