[PDF] Top 20 Repression of Dpp targets in the Drosophila wing by Brinker
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Repression of Dpp targets in the Drosophila wing by Brinker
... The DBD of Brk alone has no repressor activity If Brk represses simply by binding-site competition, a protein consisting primarily of the DBD should be capable of doing this. Residues 44-99 have previously been shown to ... See full document
11
Bridging Decapentaplegic and Wingless signaling in Drosophila wings through repression of naked cuticle by Brinker
... direct repression of nkd by Brk is underscored by three of our ...the repression of nkd by Brk is functionally ...developing wing, we found that the loss of brk de-represses nkd ...adult wing, ... See full document
10
Activation and repression activities of ash2 in Drosophila wing imaginal discs
... the wing depends on positional cues established along the AP axis of the wing imaginal disc (Biehs et ...2000). Dpp diffuses from the AP boundary and activates target genes in a threshold-dependent ... See full document
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Activin receptor inhibition by Smad2 regulates Drosophila wing disc patterning through BMP response elements
... of Brinker and Mad to the activation element of Dpp target genes in the wing (Weiss et ...of wing widening due to cavalier Baboon signaling in the absence of ...larval wing disc ... See full document
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Differing strategies for the establishment and maintenance of teashirt and homothorax repression in the Drosophila wing
... that Dpp might play an early role during the establishment of tsh repression in the second ...strong dpp hypomorphic combination is not sufficient to de-repress tsh in the distal wing disc ... See full document
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Ligand dependent de repression via EcR/USP acts as a gate to coordinate the differentiation of sensory neurons in the Drosophila wing
... The SOPs are born in a specific temporal sequence in the wing disc (Huang et al., 1991). The first SOPs arise in the third instar, 20-30 hours before pupariation; they include GSR, ACV and L3-2 along the third ... See full document
10
Positioning and differentiation of veins in the Drosophila wing
... of dpp expression in ...disc, dpp is also required for the differentiation of veins, and both loss or ectopic expression of dpp have dramatic effects on vein formation that are independent of its ... See full document
10
Growth regulation by Dpp: an essential role for Brinker and a non essential role for graded signaling levels
... the Drosophila wing imaginal disc support the hierarchical relationship between patterning and ...The wing disc is first patterned into compartments, which then function as units of size (Day and ... See full document
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Multiple modular promoter elements drive graded brinker expression in response to the Dpp morphogen gradient
... that repression of adjacent activators in individual modules by the Shn/Mad/Med complex has a limited ...co-repressors. Drosophila C-terminal Binding Protein (dCtBP), a paradigmatic example of a short-range ... See full document
10
Mutual repression between msh and Iro C is an essential component of the boundary between body wall and wing in Drosophila
... mutual repression between Iro-C and msh is also manifested by their respective ...mutual repression may occur there to establish the subdivision between these neighboring ...and Dpp (Cavodeassi et ... See full document
10
Dpp signaling inhibits proliferation in the Drosophila wing by Omb dependent regional control of bantam
... of Dpp signaling by expressing tkv-RNAi, Dad or brk in the omb-Gal4 or dpp-Gal4 domain in all cases induced increased medial cell proliferation ...direct repression of omb ...nub>brk wing ... See full document
6
brinker and optomotor blind act coordinately to initiate development of the L5 wing vein primordium in Drosophila
... the wing, respectively, it is informative to compare the mechanisms by which positional information is converted into vein initiation programs in these two ...the wing, which are mediated by the borders of ... See full document
12
The brinker gradient controls wing growth in Drosophila
... brk wing discs are bigger than wild-type ...the wing pouch of nub-Gal4>UAS-dad discs in which Dpp function is obliterated or much ...alter dpp expression (Fig. 4A-E). And, third, the ... See full document
10
dTcf antagonises Wingless signalling during the development and patterning of the wing in Drosophila
... of Drosophila Tcf (dTcf) on signalling by Wingless, a Drosophila member of the Wnt ...the wing antagonises Wingless ...the Drosophila homologue of β catenin, do not appear to be sufficient to ... See full document
8
Collaboration between Smads and a Hox protein in target gene repression
... or repression. We find that two Smad proteins, effectors of the Drosophila Dpp/TGF-  pathway, that are genetically required for the activation of the spalt ( sal ) gene in the wing, ... See full document
8
Excessive Dpp signaling induces cardial apoptosis through dTAK1 and dJNK during late embryogenesis of Drosophila
... ectopic Dpp signaling can induce cardial apop- tosis, and found that overexpression of dpp, using 69B- gal4 (69B>dpp), phenocopied the raw mutant pheno- types (Figure ...ectopic dpp was ... See full document
19
Without children is required for Stat mediated zfh1 transcription and for germline stem cell differentiation
... Jak/ Stat signalling in niche support cells regulates dpp transcription to control germline stem cell maintenance in the Drosophila ovary.. Dissection and staining of Drosophila larval o[r] ... See full document
9
Differential roles of the Drosophila EMT-inducing transcription factors Snail and Serpent in driving primary tumour growth.
... two Drosophila transcription factors, the classic EMT inducer Snail and the Drosophila orthologue of hGATAs4/6, Serpent, which drives an alternative mechanism of EMT; both Snail and GATA are specifically ... See full document
17
Cytonemes as specialized signaling filopodia
... Cytonemes may nevertheless be selective conduits. Development is characterized by complex geometries, by multiple signaling centers in developmental fields that may be closely juxtaposed, and by a limited and shared ... See full document
8
Genetic Analysis of Punt, a Type II Dpp Receptor That Functions Throughout the Drosophila melanogaster Life Cycle
... The tight correspondence be- tween dpp and punt mutant phenotypes prompts us to suggest that (1) Dpp repeatedly functions as the Punt ligand throughout the Drosophila life cycle, and (2)[r] ... See full document
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