[PDF] Top 20 Review Article Prognostic value of PD-L1 expression in non-small cell lung cancer: a meta-analysis

... that PD-L1 higher expression was significantly associated with good prognosis in Western patients and no heterogeneity was found in this ...and PD-LI expression may be a fine curative ... See full document

... of PD-L1 with the clinicopathological features and prognosis of patients with colon ...that PD-L1 expression is significantly elevated in tumor ...Its expression was not ... See full document

... Normally, PD-L1 expression maintains the homeostasis of the immune ...the PD-1/PD-L1 path- way can limit autoimmunity and inhibit the activity of T lymphocytes under an ... See full document

... to cancer cell invasion and ...our meta-analy- sis. The results of our meta-analysis supported that the function of the lymph node metastasis might be dependent on ... See full document

... The expression pro fi les of CD274 (PD-L1) in human tumors have been ...protein expression, except tumor ...of PD-L1 with its receptor PD-1 on T cells delivers a signal ... See full document

... the PD-1 receptor have shown unpre- cedented rates of durable clinical responses in patients with various cancer ...that PD-1 or PD-L1 inhibitor improved overall survival compared with ... See full document

... IgG4 PD-1 immune checkpoint inhibitor antibodies, were previously reported in the treatment of NSCLC [14, ...protein PD-L1, is currently in clinical trials as an immunotherapy for several types of ... See full document

... of PD-L1 positivity in prognostic assessment of lung cancer is still controversial [34, 35], due to the inconsistent results of PD-L1 expression and patient out- ... See full document

... with lung cancer were included in this ...Our analysis indicates that NSCLC patients with Bcl-2-positive expression have a better prognosis than those with Bcl-2-negative expression in ... See full document

... the expression of PD-L1 in EGFR mutant NSCLC cells but not in those with wild-type EGFR, indicating that the expression of PD-L1 might be dependent on EGFR signaling conferred by ... See full document

... Two authors (Bingjia Li and Xiaoyu Huang) independently extracted the data. We checked the data very carefully. The following information was extracted from the trials: first author, year of publication, number of ... See full document

... decreased expression of PTEN was associated with a shorter DFS as well as a shorter ...the prognostic value of decreased PTEN expression on OS, PTEN expression levels can also inform on ... See full document

... CD133-positive non-small cell lung cancer (NSCLC) and clinicopathological features and its impact on ...This meta-analysis was done using RevMan ...included. ... See full document

... potential prognostic biomarkers for prognosis (Table 3). Our meta-analysis looked into six lncRNAs (PVT1, AFAP1-AS1, LINC01133 and ANRIL, UCA1, MALAT-1, MEG3) whose prognostic roles have been ... See full document

... in lung adenocarcinoma patients(HR = ...miR-126 expression was a negative prognostic factor for both progression free sur- vival (HR ...our analysis showed that elevated miR-126 ... See full document

... of Lung Cancer World Conference on Lung Cancer annual meeting and European Society of Medical Oncology annual meeting were also searched from 2012 to 2017 for relevant ...this review to ... See full document

... the prognostic role of MVD on NSCLC on different stages and histological ...When analysis was strictly restricted to studies mainly on different clinical stages, we found that there was no remarkable ... See full document

... between PD-L1 expression, prognosis, and clinicopatho- logic features was investigated; 3) the expression of PD-L1 was categorized into high (positive) and low (negative) groups; ... See full document

... Ang-2 expression between NSCLC tissues and normal ...the expression of Ang-2 in NSCLC tissues was significantly higher than that in normal lung tissues either through two-category variables or ... See full document

... a PD-1/PD-L1 blockade could achieve more long-term control of tumor growth through prolonging PFS, and possibly translate into increased ...by PD-1/ PD-L1 inhibitors in patients ... See full document