[PDF] Top 20 Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection.
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Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection.
... 3345 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest Viral RNA was extracted from plasma samples collected from five individuals during the period of viremia before sero[r] ... See full document
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Vaccine-Elicited V3 Loop-Specific Antibodies in Rhesus Monkeys and Control of a Simian-Human Immunodeficiency Virus Expressing a Primary Patient Human Immunodeficiency Virus Type 1 Isolate Envelope
... sured neutralizing antibodies in postchallenge serum samples. Postchallenge neutralization titers increased at 4 weeks post- challenge in the serum of one animal (321-94) and declined steadily thereafter (Fig. 2). The ... See full document
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Apoptosis Induced by Infection of Primary Brain Cultures with Diverse Human Immunodeficiency Virus Type 1 Isolates: Evidence for a Role of the Envelope
... HIV-1 infection have been proposed based on in vitro studies (37); these include the HIV-1 gp120 and Tat proteins, as well as factors secreted by HIV-1-infected or -activated macrophages and ... See full document
10
Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection.
... of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency viruses (SIV) is unique to primate lentiviruses, having no counterpart in other animal ... See full document
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Primary Human Immunodeficiency Virus Type 1 (HIV-1) Infection during HIV-1 Gag Vaccination
... for human immunodeficiency virus type 1 (HIV-1) remains an elusive ...immunity upon HIV-1 infection is ...HIV-1 infection before completing a ... See full document
8
Herpes simplex virus type 2 infection increases human immunodeficiency virus type 1 entry into human primary macrophages
... viral envelope glycoproteins with the host cell receptors, CD4, and one of two coreceptors CCR5 or ...HIV-1 infection have shown that most patients harbour R5-tropic virus populations soon ... See full document
6
Complex Determinants in Human Immunodeficiency Virus Type 1 Envelope gp120 Mediate CXCR4-Dependent Infection of Macrophages
... from primary PBMC, cultured PBMC, and mono- cyte-derived macrophages (MDM) was extracted as described previously (63, ...and human apoB as a genomic template control, as previously described ...using ... See full document
12
Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates
... preventive human immunodeficiency virus type 1 (HIV-1) vaccine is an essential part of the strategy to eradicate ...neutralize primary isolate (tier 2) HIV-1 strains can ... See full document
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Compartmentalization of Surface Envelope Glycoprotein of Human Immunodeficiency Virus Type 1 during Acute and Chronic Infection
... the external environment in the form of immune surveillance and the availability of target ...of primary viruses isolated from peripheral blood (squares) in comparison with those from rectal samples ... See full document
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Envelope-Dependent, Cyclophilin-Independent Effects of Glycosaminoglycans on Human Immunodeficiency Virus Type 1 Attachment and Infection
... HXB envelope with that of ADA, JRFL, YU2, ...KpnI-BamHI envelope-containing fragments from pro- viral or envelope expression ...chimeric envelope gene derived from pIIIB/V3/JRFL (17) was ... See full document
12
Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection
... assess selection (26). Generally speaking, of ⬎ 1 indicates diversifying ...variable selection intensities among sites within protein-coding DNA ...fying selection, ...and 1 ... See full document
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Molecular Evolution Analysis of the Human Immunodeficiency Virus Type 1 Envelope in Simian/Human Immunodeficiency Virus-Infected Macaques: Implications for Challenge Dose Selection
... when sequences from week 12 postchallenge were ...the virus challenge dose and the number of variants transmitted is in agreement with the findings of Liu et ...variants upon subse- quent exposures, ... See full document
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Importin 7 May Be Dispensable for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus Infection of Primary Macrophages
... HIV-1 infection of HeLa ...(siRNA) sequences (DNA target sequences 5 ⬘ -GGCAGGTG TTATCTATCTG-3 ⬘ [Ambion 17721] or 5 ⬘ -GATGGAGCCC TGCATATGA-3 ⬘ [IPO7-1395]; QIAGEN [5]) or a nonspecific ... See full document
6
Nuclear Import of the Preintegration Complex Is Blocked upon Infection by Human Immunodeficiency Virus Type 1 in Mouse Cells
... acid-rich sequences that interact with importin  through the adapter importin ...a protein implicated in the regulation of gene expression and cellular stress ...of human cells (15). The second is ... See full document
12
Matrix and Envelope Coevolution Revealed in a Patient Monitored since Primary Infection with Human Immunodeficiency Virus Type 1
... into virus particles (ex- pressed as the ratio of gp120 to p24) differed between cell types, but markedly low levels of CT-truncated Env incorpo- ration and the rescue of Env incorporation by matrix mutations were ... See full document
15
A Mutation in the Human Immunodeficiency Virus Type 1 Gag Protein Destabilizes the Interaction of the Envelope Protein Subunits gp120 and gp41
... HIV-1 envelope protein is internalized from the plasma membrane via a tyrosine-based endocytic motif ...9A). Virus particles were produced by 293T transfection and assessed for single- cycle ... See full document
13
Cellular Gene Expression upon Human Immunodeficiency Virus Type 1 Infection of CD4+-T-Cell Lines
... a specific role in the HIV-1 life ...line specific; however, the majority, including enzymes involved in cholesterol biosynthesis, of changes were regulated in most infected cell ...HIV-1 ... See full document
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The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release.
... Because of its structural similarity to the membrane protein M2 encoded by influenza virus and the previously reported 4- to 10-fold reduction in progeny virion production associated wit[r] ... See full document
9
Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope protein.
... Here we have analyzed the biosynthesis of the HIV-1 env protein in detail by examining the efficiency, kinetics, and subcellular locations of several early and late folding events, inclu[r] ... See full document
9
Role of Cholesterol in Human Immunodeficiency Virus Type 1 Envelope Protein-Mediated Fusion with Host Cells
... by envelope glycoproteins from HIV-1 isolates that utilize CXCR4 and CCR5, as well as chemotaxis triggered by the chemokines SDF-1␣ and MIP-1, respectively ... See full document
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