[PDF] Top 20 A SIGNIFICANT METHOD TO EXPLORE DNA DAMAGE IN LYMPHOCYTES
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A SIGNIFICANT METHOD TO EXPLORE DNA DAMAGE IN LYMPHOCYTES
... The DNA is a stable and well protected molecule composed of two chains of that coil around each other to form a double helix for carrying genetic instructions used in growth, development, functioning and ... See full document
6
Indigenous Purple Vegetable Extracts Protect against Hydrogen Peroxide Induced DNA Damage in Human Lymphocytes
... protect DNA from oxidative damage was also evalu- ...tail DNA% and tail moment in the ...tecting DNA in lymphocytes from oxidative ... See full document
9
Measurement of DNA damage by terminal deoxynucleotidyl transferase reaction
... presented method, DNA damage in cells cultured in medium without serum was evaluated (Figure ...induced DNA damage in a time-dependent manner. A significant correlation was ... See full document
5
Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences
... oxidative DNA damage. The present study determined whether oxidative DNA damage was randomly distributed or whether it was localized in specific sequences in either the nuclear or ... See full document
9
GENOPROTECTIVE EFFECTS OF ETHANOLIC STEM EXTRACTS OF TINOSPORA CORDIFOLIA ON SODIUM ARSENITE INDUCED DNA DAMAGE IN SWISS MICE LYMPHOCYTES BY COMET ASSAY
... facilitate significant protection against the oxidative damage of biomolecules such as proteins, DNA, and lipids ...the DNA damage against radiations through several mechanisms ... See full document
5
Antioxidant activity of herbaceous plant extracts protect against hydrogenperoxide induced DNA damage in human lymphocytes
... oxidative damage, thus limiting the risk of various degenerative diseases associated with oxidative stress and tending to be potent free radical ...single method due to the complex nature of plants, in ... See full document
10
The Repair of DNA Damage Induced in Human Peripheral Lymphocytes with Styrene Oxide
... cell damage better than ...the damage becomes appa- ...cell damage caused by SO does not significantly depend on the time of ...the DNA damage during the first hour of the treatment. ... See full document
6
Early and late skin reactions to radiotherapy for breast cancer and their correlation with radiation induced DNA damage in lymphocytes
... a significant correlation has been demonstrated, using new methodologies, between five single-nucleotide polymorphisms (SNPs) and the risk of radiation-induced nor- mal tissue reactions in a small group of breast ... See full document
9
EFFECT OF PROPOLIS AND ITS POLYPHENOLIC/FLAVONOIDS COMPOUNDS ON DNA DAMAGE INDUCED BY RADIATION TO MOUSE LYMPHOCYTES
... Decreased damage is associated with decreased tail DNA content and indicates a protective effect of propolis and related polyphenolic compounds given to mice before and/or after irradiation with dose of 9 ... See full document
8
In Vitro Investigation of DNA Damage Induced by the DNA Cross Linking Agents Oxaliplatin and Satraplatin in Lymphocytes of Colorectal Cancer Patients
... several DNA lesions, including DNA in- terstrand ...Many DNA interstrand crosslinks lesions can be generated by plati- num-based chemotherapeutic ...investigated DNA interstrand crosslinks ... See full document
12
Zinc, oxidative stress, genetic background and immunosenescence: implications for healthy ageing
... a method to quantify zinc importer (hZIP), zinc exporter (ZnT) and intracellular free zinc by flow cytometry was ...or DNA damage, depend- ing on the doses and individual characteristics, there is a ... See full document
8
AMELIORATIVE EFFECT OF EUGENOL AND ANETHOLE ON ARSENIC INDUCED OXIDATIVE DNA DAMAGE IN CULTURED HUMAN PERIPHERAL BLOOD LYMPHOCYTES
... oxidative DNA damage in peripheral blood ...when lymphocytes were treated with sodium ...a significant decrease in the tail moment and lipid peroxidation in cultured peripheral blood ... See full document
5
The prognostic value of DNA damage level in peripheral blood lymphocytes of chemotherapy-naïve patients with germ cell cancer
... HR factors including PARP (Poly(ADP-ribose) polymerase) can also modulate CDDP-related DNA repair capacity in GCTs [30]. It has been shown that PARP protein is significantly overexpressed in GCTs compared to ... See full document
10
The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats
... a significant decrease in serum VEGF level in silymarin supplemen- ted rats compared to NDEA treated ...a significant decrease in serum VEGF level in EGb supplemented rats compared to NDEA treated ... See full document
12
Sample Preservation and Plant Sex Prediction in white Guinea yam ( Dioscorea rotundata(Poir.) Seedlings
... like DNA, which degrade over time, from plant tissue samples collected for experimental purposes is always challenging for many research projects ...preservation method that maintain DNA integrity ... See full document
11
p16 and ARF: activation of teenage proteins in old age
... yet to be established. Studies focused on the tumor suppressor p53 have revealed diverse results regarding the role of this key component of the senescence path- way during aging. In mouse models, the deletion of p53 has ... See full document
5
Exposure to ultraviolet radiation causes apoptosis in developing sea urchin embryos
... DNA damage can be caused directly, by exposure to UVR as a result of absorbing photons of UVR, or indirectly, through the production of ROS (Imlay and Linn, 1988; Peak and Peak, ...This DNA ... See full document
7
Synthesis of PLGA nanoparticles of tea polyphenols and their strong in vivo protective effect against chemically induced DNA damage
... of DNA repair genes (XRCC1, XRCC3, and ERCC1) significantly compared with Group ...tested DNA dam- age and repair responsive genes in comparison to Group ...more significant protection compared with ... See full document
12
PARP 1 inhibitor monotherapy and combination therapy in a preclinical mouse model of Brca2 mutant breast cancer
... a significant number of human breast cancers ...for DNA replication and our results demon- strate that this is not the case in all cell lines (we have tested other lines in which TopBP1 is essential for S ... See full document
49
Prevention of DNA damage and anticarcinogenic activity of Activia in a preclinical model.
... of DNA damage (Brennan and Garrett, 2016), no record in the literature about the (anti)carcinogenic, (anti)genotoxic or (anti)mutagenic potential of Activia ® and DanRegularis strains was found, which makes ... See full document
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