[PDF] Top 20 In Silico Pattern-Based Analysis of the Human Cytomegalovirus Genome
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In Silico Pattern-Based Analysis of the Human Cytomegalovirus Genome
... Teiresias pattern discovery algorithm (25, 26) to identify patterns that are shared by k or more input ...a pattern-based approach to the prob- lem of protein annotation ...out pattern ... See full document
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In silico regulatory analysis for exploring human disease progression
... al, Genome Informat- ics, 19, 2007] suggest that perhaps most of 152 TF training sets used in this work are represented by essentially incomplete, non-representative and bias ... See full document
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From Genome-Based In Silico Predictions to Ex Vivo Verification of Leprosy Diagnosis
... The detection of hundreds of thousands of new cases of leprosy every year suggests that transmission of Mycobacterium leprae infection still continues. Unfortunately, tools for identification of asymptomatic disease ... See full document
8
In Silico Design of a Multimeric Polytope as a Highly Immunogenic DNA Vaccine Against Human Cytomegalovirus
... in silico techniques that facilitate epitope mapping on protein antigens are preferred for EV analysis ...in silico prediction methods with in vitro and in vivo verification [20, ... See full document
11
Inhibition of Human Cytomegalovirus pUL89 Terminase Subunit Blocks Virus Replication and Genome Cleavage
... gel analysis showed that the 153-bp fragment was the smallest degraded fragment ...gel analysis showed that the 60-bp fragment was cleaved by pUL89-C under normal reaction ... See full document
14
A Novel Pattern Matching Algorithm in Genome Sequence Analysis
... Every human has his/her unique genes. Genes are made up of DNA. DNA is contained in each living cell of an organism, and it is the carrier of that organism’s genetic code. The genetic code is a set of Sequences ... See full document
8
Human Cytomegalovirus pUL93 Is Required for Viral Genome Cleavage and Packaging
... structural analysis of the nucleus and the cytoplasm of WT- TB40/E-infected cells revealed the presence of empty (A-), scaffold-containing (B-), and genome-containing (C-) capsids in the nucleus, and ... See full document
5
Heterologous Viral Promoters Incorporated into the Human Cytomegalovirus Genome Are Silenced during Experimental Latency
... Here we have analyzed the expression pattern not of a cellular promoter but of heterologous viral promoters within the context of a herpesvirus genome. Such a scenario is more common than may be initially ... See full document
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The Essential Human Cytomegalovirus Proteins pUL77 and pUL93 Are Structural Components Necessary for Viral Genome Encapsidation
... parental genome), with the expected BglII restriction fragments indicated as black ...HCMV genome. The left part shows the BglII restriction pattern of the parental BAC (lane 1) compared to that of ... See full document
16
High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive Recombination
... Phylogenetic network analyses were performed with SplitsTree v4.13.1 (51). Neighbor-net split networks were constructed by using un- corrected p-distances and excluding gap sites. Network construction us- ing the ... See full document
23
Analysis of Human Cytomegalovirus oriLyt Sequence Requirements in the Context of the Viral Genome
... pOri6K-Kan1 and pOri6K-Kan4, which contain a kanamycin resistance marker plus one FLP recognition target (FRT) site in different orientations, and the bacterial origin of replication R6K ␥ (34), a 1.0-kbp fragment ... See full document
12
Analysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome
... Sequence analysis of GPCMV revealed a genome length of 232,678 bp with a GC content of ...sequence analysis that had sub- stantial overlap with other adjacent or complementary GPCMV ORFs that ... See full document
11
Defined large-scale alterations of the human cytomegalovirus genome constructed by cotransfection of overlapping cosmids.
... Several biological properties of CMV contribute to the dif- ficulties in generating defined viral recombinants. CMV has a narrow host range in vitro and replicates slowly, reaching peak levels of DNA synthesis ... See full document
5
Sequencing and analysis of an Irish human genome
... This successful application of imputation of unknown genotypes in our Irish individual prompted us to test whether haplotype information could also be used to improve SNP calling in whole genome data with low ... See full document
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Structure of the rat cytomegalovirus genome termini.
... Sequence of RCMV DNA termini. The sequences of the terminal 648 bp of the left end and terminal 1,088 bp of the right end of the RCMV genome are depicted in Fig. 2. For each terminus, the sequence was derived from ... See full document
9
Analysis of landscape pattern based on the point pattern method
... lattice pattern is tiled. Subsequently, the point pattern tools, which are found in the toolbox for spatial statistics analyses in the ARCGIS software, were used to perform the analysis of Ripley's K ... See full document
5
Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication
... Human cytomegalovirus (HCMV) in clinical material cannot replicate efficiently in vitro until it has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the passaged strains used for ... See full document
19
Pattern of the Epitope-Specific IgG/IgM Response against Human Cytomegalovirus in Patients with Multiple Myeloma
... uman cytomegalovirus (HCMV), one of eight human her- pesviruses, represents a major human pathogen causing se- vere disease in newborns and immunocompromised patients, ...causing human cancer, ... See full document
7
Complete DNA Sequence of the Rat Cytomegalovirus Genome
... complete genome sequence of the Maastricht strain of rat cytomegalovirus ...RCMV genome has a length of 229,896 bp and is arranged as a single unique sequence flanked by 504-bp terminal direct ...and ... See full document
10
In-silico human genomics with GeneCards
... groups from 16 countries. The strategic aim of the consortium is the use of systems biology to enable novel chronic kidney disease (CKD) diagnosis and treatment. GeneCards is being used as a consortium tool in ways that ... See full document
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