[PDF] Top 20 Specification and maintenance of the spinal cord stem zone
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Specification and maintenance of the spinal cord stem zone
... of stem zone genes takes place many hours later, suggesting that FGF4 indirectly promotes formation of the stem zone (Storey et ...induce stem zone ...of stem zone ... See full document
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Doublesex controls specification and maintenance of the gonad stem cell niches in Drosophila
... Sex-specific development of the gonads is a key aspect of sexual dimorphism that is regulated by Doublesex/Mab3-related transcription factors (DMRTs) in diverse animal species. We find that in mutants for Drosophila dsx, ... See full document
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FGF signaling controls Shh-dependent oligodendroglial fate specification in the ventral spinal cord
... in spinal cord progenitor cells is not efficient in inducing Olig2 expression in progenitor cells in their endogenous context of the neural tube or when Shh signaling activity is ...developing spinal ... See full document
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Region specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord
... the spinal cord, whereas ventral neuronal specification and ganglionic eminence development in the Shh N/– telencephalon were severely impaired, suggesting that telencephalic patterning is more ... See full document
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Histone deacetylase 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signalling
... and maintenance of cell memory during embryonic development (reviewed by Turner, ...neuronal specification are severely impaired in distinct CNS territories of mutant embryos within which strong ectopic ... See full document
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A Notch regulated proliferative stem cell zone in the developing spinal cord is an ancestral vertebrate trait
... vertebrate spinal cord is a far more complex structure than the equivalent in other ...proliferative zone generating a peripheral zone of differentiated neurons over an extended period of ... See full document
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Repression of the hindbrain developmental program by Cdx factors is required for the specification of the vertebrate spinal cord
... brain stem (reviewed by Borday et ...the spinal cord remains unsegmented, although an anterior-posterior iterative arrangement of various neuronal populations can be seen to different degrees in ... See full document
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Advances in stem cell therapy for spinal cord injury
... neural stem cells in mammals was first reported in 1992 by Reynolds and Weiss ...subventricular zone lining the lateral ventricles of the forebrain (40, 41), the dentate gyrus of the hip- pocampus (42), and ... See full document
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Selective killing of spinal cord neural stem cells impairs locomotor recovery in a mouse model of spinal cord injury
... is lining the central canal of the SC, arranged in specific germinal niches. Such niches show a different cyto- architecture, if compared with niches of the brain sub- ventricular zone (SVZ), [6, 7]. A key ... See full document
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Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord
... dorsoventral specification of neural progenitors in the Drosophila ventral neuroectoderm and in the ventricular zone of the vertebrate spinal ...ventral cord appears to be restricted to ... See full document
12
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation
... injured spinal and optic axons in ...injured spinal axons into the ...of spinal sensory axons into a peripheral nerve graft in WT and Folr1 +/– mice with and ... See full document
15
In vivo conversion of rat astrocytes into neuronal cells through neural stem cells in injured spinal cord with a single zinc-finger transcription factor
... intraperitoneal injections of ketamine (100 mg/kg) and xylazine (10 mg/kg). A 3 cm × 6 cm area was then lon- gitudinally shaved, the exposed skin was cleaned, and an approximately 4 cm incision was made using a #10 blade ... See full document
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Safety and neurological assessments after autologous transplantation of bone marrow mesenchymal stem cells in subjects with chronic spinal cord injury
... Variability of the results may be caused by the different numbers of cells, routes and regimen of administration. These are considered key factors for the development of optimized cell-based therapies [37]. The dose and ... See full document
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Patterning of the vertebrate ventral spinal cord
... ventral spinal cord respond to Shh-N? The extended period of Shh-N availability during ventral patterning raises the question of how long cells require or can respond to the ...ventral spinal ... See full document
12
Transcranial electrical stimulation motor-evoked potentials in a spinal cord ischaemia rabbit model
... that spinal cord function was normal and blood flow to the spinal cord was approximately 85% of the control value after ligation of the segmental arteries at 3 consecutive levels ...of ... See full document
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Defining the Role of Mechanical Signals During Nerve Root Compression in the Development of Sustained Pain and Neurophysiological Correlates that Develop in the Injured Tissue and Spinal Cord
... 2005). Spinal excitability also mediates behavioral responses in nerve root injury (Ramer et ...the spinal cord, while enhanced behavioral sensitivity is associated with an increase in the amplitude ... See full document
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Health promotion and cardiovascular risk reduction in people with spinal cord injury: physical activity, healthy diet and maintenance after discharge— protocol for a prospective national cohort study and a preintervention- postintervention study
... for Spinal Cord Injuries in Eastern Denmark (CSCI) generally includes functional training, strength training, cardiovascular exercise and fine motor training of the upper ... See full document
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Improvement of renal function after human umbilical cord mesenchymal stem cell treatment on chronic renal failure and thoracic spinal cord entrapment: a case report
... thoracic spinal cord entrapment with paraplegic condition for 6 months and chronic renal failure on hemodialysis for 2 ...of spinal shock was found in a physical examination during a neurological ... See full document
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Original Article The effect of umbilical cord blood stem cells and micro connection bridge system on rat spinal cord injury
... mesenchymal stem cells, such as promoting the bone growth in vitro and in vivo, the cartilage formation and differ- entiation potential and etc, but their immuno- logical behaviors and transcriptome sequenc- ing ... See full document
7
Harnessing the HDAC-histone deacetylase enzymes, inhibitors and how these can be utilised in tissue engineering.
... In conclusion, the fi eld of HDACis in tissue engineering is still in its infancy compared with cancer research where at least 4 HDACis have achieved clinical approval, with many others in late-stage clinical trials. 192 ... See full document
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