[PDF] Top 20 Statins reduce all-cause mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis of observational studies

... included studies were RCTs, but obser- vational studies. Although meta-analysis with an RCT is usually preferred, meta-analysis with non-RCT studies is commonly accepted ... See full document

... a systematic prognosis review following criteria commonly published by scientific associations, and we also included observational studies to evaluate our clinical ...most studies were ... See full document

... large meta-analysis of observational cohorts and randomised intervention studies [18] with 849,412 and 30,716 participants, respectively, reported an inverse correlation between serum 25(OH)D ... See full document

... of all-cause mortality, cardiovascular mortality, and cardiovascular mor- ...and observational studies will be recorded ... See full document

... a systematic review and meta-analysis of observational ...epidemiological studies. Eligible studies will be observational studies reporting study-specific ... See full document

... a disease of the elderly population who have comorbidities such as DM, HTN and CAD, known risk factors associated with ...kidney disease. In a meta-analysis of observational ... See full document

... this systematic review have important implications for research and policy around COPD diag- nosis, for example, in estimating the return on invest- ment in screening and case detection strategies for ... See full document

... ally cause reduced quality of life, disability and mortality of patients ...well-known pulmonary manifestation with the prevalence around 5–10% [36–38]. Studies reported that ILD and ... See full document

... 2) studies with adults aged .18 years and diagnosed with COPD; 3) studies comparing triple therapy with nontriple therapy; 4) trials lasting at least 4 weeks; 5) studies reporting at least one of the ... See full document

... Although all included studies were of moderate to high quality, there are some ...the meta-analysis of cohort studies with confounder adjusted analysis helps limit potential ... See full document

... our meta-analysis need to be empha- ...the studies. The validity of a meta-analysis mostly depends on the quality of the included ...those studies were performed and might ... See full document

... When it was possible to investigate gender sepa- rately, heterogeneity disappeared in both prospective and cross-sectional studies, but the associations became nonsignif icant in the prospective studies, ... See full document

... this review, there is an urgent need for future research focusing on: (1) The elucidation of the complex interrelationship between the pathophysiology and outcomes of stroke in these patients that might favour the ... See full document

... of studies included in this review had a low risk of bias in their methodological ...for studies during the review process was wrong diag- nostic criteria for PH ...for pulmonary ... See full document

... Our analysis thus far suggests that the content of PC integration of guidelines/pathways is statistically the same between cancer and CHF/COPD. Furthermore, it does appear to constitute a barrier that is actually ... See full document

... (FDA) review and was approved for the management of stable COPD. All the current medications contain a quaternary ammonium that limits their systemic absorption and penetration across the blood–brain ... See full document

... files. All-cause mortality was assessed using the vital status ...in mortality rates were tested using the chi-square ...and all-cause mortality. All analyses ... See full document

... RB all contributed to study design, interpretation of results, manuscript writing, and reviewed the final manuscript prior to ...submission. All authors had full access to all of the data (including ... See full document

... a meta-regression to ex- plore the independent influences of these factors on het- erogeneity and then sensitivity analysis on the main effects by excluding all of the studies one by one to ... See full document

... © Queen ’ s Printer and Controller of HMSO 2013. This work was produced by O ’ Mara-Eves et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced ... See full document