[PDF] Top 20 Stomach development, stem cells and disease

... After stomach specification, several other TFs are involved in stomach regionalization and ...mouse stomach differentiates into two principal derivatives along the proximal-distal axis: the ... See full document

... nological rejection and embryo destruction can be overcome. The era of real cell replacement therapy could start with the onset of clinical trials after basic researchers and clinicians take account of the lessons ... See full document

... of cells and macromolecules known as the blood- brain-barrier (BBB) prevents most substances from entering the ...neural stem cells (NSCs), the precursor cells to neurons and glia in the ... See full document

... s disease (AD), a common neurodegenerative disorder associated with gradually to dramatic neuronal death, synaptic loss and dementia, is considered to be one of the most obscure and intractable brain disorders in ... See full document

... Parkinson’s disease (PD) therapy is the pharmacological replacement of the loss of the dopaminergic nigrostriatal pathway using drugs such as dopamine agonists and ...dopaminergic cells can survive long ... See full document

... of cells have been explored, each with their own benefits and ...pluripotent stem cells possess an embryonic-like state and therefore have a high proliferative capacity, but they also pose a risk of ... See full document

... mesenchymal stem cells can be used as cellular vehicles to deliver brain-derived neurotrophic factor to the retina in order to preserve retinal architecture and function in a rat model of ... See full document

... Besides resident ISC, circulating multipotent stem cells of bone marrow (BM) origin represent another poten- tial source for intestinal regeneration. Indeed, over the last years, several studies have ... See full document

... embryo-derived cells? The answer, of course, should not be based on ideological or religious beliefs or hopes, but on sound scientific ...of cells, a number of recent studies revealed important differences ... See full document

... these cells to a proliferative state, prior to ...these cells in the adult ...of Stem Cell Research, Munich, Germany) developed a method to culture NSCs from the adult SEZ at the clonal level, ... See full document

... pluripotent stem (iPS) cells are generated by epigenetic reprogramming of somatic cells through the exog- enous expression of transcription ...These cells, just like embryonic stem ... See full document

... the development and survival of dopaminergic neurons involving 9(*)VLJQDOOLQJ+,)_ in some way regulates the differentia- tion and production of dopaminergic neurons (Kim et ...precursor cells (e.g. for ... See full document

... Periodontitis is a disease of the periodontium characterized by irreversible loss of connective tissue attachment and supporting alveolar bone. These changes often lead to an aesthetically and functionally ... See full document

... further development of this approach was hindered by the occurrence of adverse effects, so-called graft-induced dyskinesias (GIDs), in a subgroup of patients ...respect, stem cells (SCs) could ... See full document

... In addition to HSCs, MSCs are also a part of bone marrow-derived stem cells. A meta-analy- sis showed that there is no statistical differ- ence between MSCs and HSCs in the treatment of liver disease ... See full document

... the development of differentiation protocols for human pluripotent stem cells (PSCs), have jointly engendered new disease models based on induced PSCs (iPSCs) derived from the som- atic ... See full document

... the stem cell field have opened new win- dows to generate region-specific and subtypes-specific neural progenitors through direct reprogramming from somatic cells, which will set up a new concept for AD ... See full document

... the cells’ survival, respectively ...in stem cells are considered positively as a way of survival optimization for both transplanted cells and cardiac and vascular cells of the host ... See full document

... conclusion, stem cells (both normal and cancerous) are a valuable tool in the drug discovery ...tumorigenic stem cell behavior (Figure ...embryonic stem cells are limited due to ethical ... See full document

... recent development of 3D stem cell-derived culture systems has allowed the generation and the long-term expansion of adult tissues far beyond the predicted ...parallel development of powerful genetic ... See full document